Exams for 1203 BCH

• المقرر الدراسي: Clinical Biochemistry 1 (1203) BCH

Clinical Biochemistry I

Mid. II

 

 

Q1: Put (√ ) or ( X ) , Correct ( X ) one.

 

1.All carrier molecules in the ETC are proteins and loosely bound to the prosthetic group  . (   )

 

 

 

2. In ETC: For every two NADH2 , two O2 is reduced to one H2O molecule . (   )

 

 

 

3. Bile produced by the gallbladder and stored in the liver. (   )

 

 

 

4. Fatty acids are recycled through four different steps process. (   )

 

 

 

5.Hydration is removal of one hydrogen atom. (   )

 

 

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Q2. Fill in the blanks.

 

1. In ETC, FADH2 results in …………….. ,while NADH2 yields ………………….  .

 

 

2.One of the insulin defects is the ………………. of ……………….. to insulin.

 

 

3. Bile salts act as ……………….. to help breakup of fat globules.

 

                        

4. Activation step of β-oxidation occur in ………………………. , this activation require ………….. ATP molecules.

 

5. In β-oxidation , carrier molecule called as ……………………                                                                                            

 

   ………………..  +………………… 6.

 

 

7. Fatty acyl CoA ∆ uses …………….. as a Co factor , while L-3-hydroxy acyl CoA uses ……………… as a Co factor.
 
 

Q3: Answer the following :

 

 A/How many ATP produced by ETC each turn and locate each one in the suitable place?

B/ write the correct name of each complex.

 

C/ Explain β-Oxidation of fatty acids.

 

First Complex:………………………………….

 

NADH        FMN            FeS              CoQ

Red.             Oxi.             Red.            Oxi.

 

NAD+        FMNH2        FeS             CoQH2

Oxi.            Red.              Oxi.             Red.

 

 

         Fumerate                 FADH2

                                         Red.

 

        Succinate                 FAD+

                                        Oxi.

Second Complex:………………………………

 

Third Complex:………………………………..

 

CoQ                    Prosthetic           Cytochrome C1

Oxi.                     Groups.              Red.

 

CoQH2                                          Cytochrome C1

Red.                                               Oxi.  

 

Fourth Complex:………………………………..

 

Cyt.C1                                          H2O

Red.                                             

Cyt.C1                                          1/2 O2 + 2H+

Oxi.                                                                                                           Best Wishes,