Exams for 1203 BCH
Clinical Biochemistry I
Mid. II
Q1: Put (√ ) or ( X ) , Correct ( X ) one.
1.All carrier molecules in the ETC are proteins and loosely bound to the prosthetic group . ( )
2. In ETC: For every two NADH2 , two O2 is reduced to one H2O molecule . ( )
3. Bile produced by the gallbladder and stored in the liver. ( )
4. Fatty acids are recycled through four different steps process. ( )
5.Hydration is removal of one hydrogen atom. ( )
=============================================================
Q2. Fill in the blanks.
1. In ETC, FADH2 results in …………….. ,while NADH2 yields …………………. .
2.One of the insulin defects is the ………………. of ……………….. to insulin.
3. Bile salts act as ……………….. to help breakup of fat globules.
4. Activation step of β-oxidation occur in ………………………. , this activation require ………….. ATP molecules.
5. In β-oxidation , carrier molecule called as ……………………
……………….. +………………… 6.
7. Fatty acyl CoA ∆ uses …………….. as a Co factor , while L-3-hydroxy acyl CoA uses ……………… as a Co factor.
Q3: Answer the following :
A/How many ATP produced by ETC each turn and locate each one in the suitable place?
B/ write the correct name of each complex.
C/ Explain β-Oxidation of fatty acids.
First Complex:………………………………….
NADH FMN FeS CoQ
Red. Oxi. Red. Oxi.
NAD+ FMNH2 FeS CoQH2
Oxi. Red. Oxi. Red.
Fumerate FADH2
Red.
Succinate FAD+
Oxi.
Second Complex:………………………………
Third Complex:………………………………..
CoQ Prosthetic Cytochrome C1
Oxi. Groups. Red.
CoQH2 Cytochrome C1
Red. Oxi.
Fourth Complex:………………………………..
Cyt.C1 H2O
Red.
Cyt.C1 1/2 O2 + 2H+
Oxi. Best Wishes,