Watermelon (Citrullus lanatus) seeds are endowed with phytonutrients that ascribe to their potent antioxidant
status. The present study proposes a facile and novel green synthesis of nanoparticles of the seed extract. The
synthesized nanoparticles showed a mean average size of 215 nm with a single significant peak and a polydispersity index (PDI) of 0.11.The electron micrographs showed spherical nanoparticles dispersed without
agglomeration The biocidal and the antiproliferative effect on cancer cell lines (HCT-116, HepG-2, HeLa) of the
nanoparticles (WMnano) was more pronounced as compared to the bulk seed extract (WMS).
Anti-proliferative and biocidal effect of watermelon (Citrullus lanatus) seed extract and its nanoformulation