Associate Professor | Associate Professor

Address: Department of Chemistry, Building No.5, Office: 2B-94; Lab: 2B-116 or 2B-84 | Phone: +966114675901-75908

Publications

Synthesis, in vitro biological activities and in silico study of dihydropyrimidines derivatives
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Synthesis of novel 5-monoalkylbarbiturate derivatives: new access to 1,2-oxazepines
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New Diethyl Ammonium Salt of Thiobarbituric Acid Derivative: Synthesis, Molecular Structure Investigations and Docking Studies
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Synthesis and dynamics studies of barbituric acid derivatives as urease inhibitors
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Crystal Structure of 7,11-bis(2,4-dichlorophenyl)-2,4-dimethyl-2,4- diazaspiro[5.5]undecane -1,3,5,9-tetraone and its computational studies
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Synthesis and Characterization of Novel Thieno-Fused Bicyclic Compounds through New Enaminone Containing Thieno[2,3-b]pyridine Scaffold
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Synthesis, and characterization of a new series of sulfite and sulfate derivatives of d-Mannitol
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Molecular structure investigation and biological evaluation of Michael adducts derived from dimedone
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Synthesis and Crystal Structures of Benzimidazole-2-thione Derivatives by Alkylation Reactions
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Synthesis, Molecular Structure Optimization, and Cytotoxicity Assay of a Novel 2-Acetyl-3-amino-5-[(2-oxopropyl)sulfanyl]-4-cyanothiophene
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Crystal structure of 5,5′-((4-(trifluoromethyl)phenyl)methylene)bis(1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione) – diethylamine – dichloromethane (1/1/1) C25H32Cl2F3N5O6
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Crystal structure of (Z)-5-(4-chlorobenzylidene)-2-thioxothiazolidin-4-one —dimethylsulfoxide (1:1), C12H12ClNO2S3
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Crystal structure of 2-amino-N-(4-methoxyphenyl)benzamide, C14H14N2O2
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Crystal structure of 3-(thiophen-2-yl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazole-1-carboxamide
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Synthesis of New Functionalized Indoles Based on Ethyl Indol-2-carboxylate
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concise synthesis and evaluation of new malonamide derivatives as potential α-glucosidase inhibitors
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Crystal structure of diethylammonium 5-((4-fluorophenyl)(6-hydroxy-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-olate, C23H30FN5O6
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Crystal structure of 1-(5-benzoyl-4-methyl-2-(phenylamino)thiophen-3-yl)ethan-1-one, a structure with Z′ = 6, C20H17NO2S
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Crystal structure of diethyl-3-methyl-4-phenylthieno[2,3-b]thiophene-2,5-dicarboxylate, C19H18O4S2
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Crystal structure of (E)-2-(bis(methylthio)methylene)-1-phenyl-3-(2-phenylhydrazono)butan-1-one, C19H20N2OS2
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Crystal structure of 2-(bis(methylthio)methylene)-1-phenylbutane-1,3-dione, C13H14O2S2
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Crystal structure of 1,1'-(propane-1,3-diyl)bis(5-methyl-1H-pyrazole-3-carbaldehyde), C14H18N4O2
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Crystal structure of 5-((4-bromophenyl)(2-hydroxy-6-oxocyclohex-1-en-1-yl)methyl)-6-hydroxy-1,3-dimethylpyrimidine-2,4(1H,3H)-dione, C19H19BrN2O5
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Synthesis, X-Ray Crystal Structures, Biological Evaluation and Molecular docking studies of a Series of Barbiturate Derivatives.
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Crystal structure of 6-hydroxy-5-((2-hydroxy-6-oxocyclohex-1-en-1-yl)(phenyl)methyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione, C19H20N2O5
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3D-QSAR Studies on Barbituric Acid Derivatives as Urease Inhibitors and the Effect of Charges on the Quality of a Model
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Synthesis, spectral, thermal, crystal structure, Hirschfeld analysis of [bis(triamine)Cadimium(II)][Cadimum(IV)tetra-bromide] complexes and their thermolysis to CdO nanoparticles
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Synthesis, antimicrobial, anti-cancer and molecular docking of two novel hitherto unreported thiophenes
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Synthesis of pyrimidine-2,4,6-trione derivatives: anti-oxidant, Anti-cancer, α-glucosidase, ß-glucuronidase inhibiton and their molecular docking studies
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Molecular Structure, Spectroscopic and DFT Computational Studies of Arylidene-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione
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Crystal structure of diethylammonium 1,3-dimethyl-2,4,6-trioxohexahydropyrimidin-5-ide, C10H19N3O3
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Crystal structure of 5-(3-fluorobenzylidene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione; C13H11FN2O3
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5-[(3-Fluorophenyl)(2-hydroxy-6-oxocyclohex-1-en-1-yl)methyl]-6-hydroxy-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
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Synthesis of Pyrazole-Thiobarbituric Acid Derivatives: Antimicrobial Activity and Docking Studies
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Synthesis, characterization and computational studies of a novel thieno[2,3-b]thiophene derivative
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Synthesis, characterization, antimicrobial activity and molecular docking studies of combined pyrazol-barbituric acid pharmacophores
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Decomposition of Intermolecular Interactions in the Crystal Structure of Some Diacetyl Platinum(II) Complexes: Combined Hirshfeld, AIM, and NBO Analyses
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Diethylenetriamine/diamines/copper (II) complexes [Cu(dien)(NN)]Br2: Synthesis, solvatochromism, thermal, electrochemistry, single crystal, Hirshfeld surface analysis and antibacterial activity
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Stereoselective synthesis of diazaspiro[5.5]undecane derivatives via base promoted [5+1] double Michael addition of N,N-dimethylbarbituric acid to diaryliedene acetones
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Tandem Knoevenagel–Michael reactions in aqueous diethylamine medium: A greener and efficient approach toward bis-dimedone derivatives
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Synthesis, crystal structure, Hirshfeld surfaces, and thermal, mechanical and dielectrical properties of cholest-5-ene
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Synthesis, physicochemical analysis of two new hemilabile ether-phosphine ligands and their first stable bis-ether-phosphine/cobalt(II) tetrahedral complexes
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Molecular structure and spectroscopic investigations combined with hypoglycemic/anticancer and docking studies of a new barbituric acid derivative
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Synthesis, molecular structure, spectral analysis, and biological activity of new malonamide derivatives as α-glucosidase inhibitors
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Crystal structure of 2-(4-oxo-2-thioxothiazolidin-3-yl)acetic acid monohydrate, C5H7NO4S2
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Synthesis, structural characterization of monodentate phosphite ligands and phosphite ruthenium complexes derived from d-mannitol
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Synthesis of new spirooxindole-pyrrolothiazole derivatives: Anti-cancer activity and molecular docking
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A highly distorted hexacoordinated silver(I) complex: synthesis, crystal structure, and DFT studies
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Crystal structure of 1,1,(3,4-dihydroxythieno[2,3-b] thiophene-2,5-diyl)bis(2-bromoethanone), C10H6Br2O4S2
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Intermolecular interactions in crystal structure, Hirshfeld surface, characterization, DFT and thermal analysis of 5-((5-bromo-1H-indol-3-yl)methylene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione indole
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Monoalkylated barbiturate derivatives: X-ray crystal structure, theoretical studies, and biological activities
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Synthesis, structure combined with conformational analysis, biological activities and docking studies of bis benzylidene cyclohexanone derivatives
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automerism aspect of thione-thiol combined with spectral investigation of some 4-amino-5-methyl-1,2,4-triazole-3-thione Schiff's bases
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Synthesis, solvatochromism and crystal structure of trans-[Cu(Et2NCH2CH2NH2)2.H2O](NO3)2 complex: Experimental with DFT combination
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Synthesis of thiobarbituric acid derivatives: In vitro α-glucosidase inhibition and molecular docking studies
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Theoretical study of organic materials based on Thieno[2,3-b]thiophene as layer of bulk heterojunction solar cells
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New spiro-oxindole constructed with pyrrolidine/thioxothiazolidin-4-one derivatives: Regioselective synthesis, X-ray crystal structures, Hirshfeld surface analysis, DFT, docking and antimicrobial studies
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Stereoselective synthesis of novel thioglycosyl heterocycles
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Analytical Studies of 6-Hydroxy-5-[(2-hydroxy- 6-oxocyclohex-1-en-1-yl)(2-nitrophenyl)methyl]-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
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Quantum chemical insight into the molecular structure of L-chemosensor 1,3-dimethyl-5-(thien-2-ylmethylene)-pyrimidine-2,4,6-(1H,3H,5H)-trione: Naked-eye colorimetric detection of copper(II) anions
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Regio- and stereoselective synthesis of new spirooxindoles via 1,3-dipolar cycloaddition reaction: Anticancer and molecular docking studies
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Synthesis, antimicrobial activity, pharmacophore modeling and molecular docking studies of new pyrazole-dimedone hybrid architectures
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New hybrid of the barbituric acid motif: synthesis, X-ray single crystal, DFT, and Hirshfeld surface analyses
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Synthesis of rare Ag(I)-malonamide complex: Single-crystal X-ray crystallography and DFT Studies
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Substituted spirooxindole derivatives as potent anticancer agents through inhibition of phosphodiesterase 1
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Catalytic Asymmetric Synthesis of Indole Derivatives as Novel α-Glucosidase Inhibitors in Vitro
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Towards Environmentally Friendlier Suzuki-Miyaura Reactions with Precursors of Pd-NHC (NHC = N-Heterocyclic Carbene) Complexes
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Unexpected Formation of Polymeric Silver(I) complexes of azine-type ligand via self assembly of Ag-salts with isatin oxamohydrazide; Synthesis, crystal structure and DFT studies
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Crystal structure of 5,5′-((3-hydroxy-4-methoxyphenyl)methylene)bis(1,3-diethyl-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one), C24H30N4O6S2
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Crystal structure of 6-hydroxy-5-((2-hydroxy-6-oxocyclohex-1-en-1-yl)(4-methoxyphenyl)methyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione.
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Chemical reactivity, molecular structure, spectroscopic and DFT computational studies of new spiroheterocycle
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Complex Clonal Diversity of Staphylococcus aureus Nasal Colonization among Community Personnel, Healthcare Workers, and Clinical Students in the Eastern Province, Saudi Arabia
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A new barbituric acid derivatives as reactive oxygen scavenger: Experimental and theoretical investigations
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Synthesis of new thiazolo-pyrrolidine–(spirooxindole) tethered to 3-acylindole as anticancer agents
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Vibrational spectral analysis, XRD-structure, computation, exo⇔endo isomerization and non-linear optical crystal of 5-((5-chloro-1H-indol-2-yl)methylene)-1,3-diethyl-2-thioxodihy-dropyrimidine-4,6 (1H,5H)-dione
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Computational studies of 2-(4-oxo-3-phenylthiazolidin-2-ylidene)malononitrile
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Design and synthesis of new substituted spirooxindoles as potential inhibitors of the MDM2–p53 interaction
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Synthesis and characterization of a spiroindolone pyrothiazole analog via X-ray, biological, and computational studies
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Synthesis and characterization of a spiroindolone pyrothiazole analog via X-ray, biological, and computational studies
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Self-assembly of azine-based hydrolysis of pyridine and isatin oxamohydrazides with AgNO3; synthesis and structural studies of a novel four coordinated Ag(I)-azine 2D coordination polymer
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Synthesis of Pyridine-Dicarboxamide-Cyclohexanone Derivatives: Anticancer and α-Glucosidase Inhibitory Activities and In Silico Study
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Synthesis, X-ray crystal structures, and anti-proliferative activities of new s-triazine-hydroxybenzylidene hydrazone derivatives
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Synthesis, X-ray crystal structures, and anti-proliferative activities of new s-triazine-hydroxybenzylidene hydrazone derivatives
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Palladate pre-catalysts for the formation of C-N and C-C bonds
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Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase
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Syntheses and X-ray crystal structures combined with conformational and Hirshfeld analyses of chalcones based on a cyclohexanone scaffold
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Synthesis of Oxindole Analogues, Biological Activity, and In Silico Studies
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ynthesis and Inhibitory Effect of Some Indole‐Pyrimidine Based Hybrid Heterocycles on α‐Glucosidase and α‐Amylase as Potential Hypoglycemic Agents
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Anticancer Indole-Based Chalcones: A Structural and Theoretical Analysis
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Mizoroki–Heck Cross‐Coupling of Acrylate Derivatives with Aryl Halides Catalyzed by Palladate Pre‐Catalysts
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Synthesis and Anti-Proliferative Assessment of Triazolo-Thiadiazepine and Triazolo-Thiadiazine Scaffolds
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Synthesis, computational studies and biological activity of oxamohydrazide derivatives bearing isatin and ferrocene scaffolds
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Synthesis, anti-proliferative activities and computational studies of spiroindolone analogue via three component reaction of olefin with isatin and sarcosine
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Three Multi Components Reaction: Synthesis and X-ray single crystal of hydroacridinone based hydrazino-s-triazine derivative as a new class of urease inhibitor
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Synthesis, crystal structure, evaluation of urease inhibition potential and the docking studies of cobalt(III) complex based on barbituric acid Schiff base ligand
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Synthesis, X-ray Single Crystal, Conformational Analysis and Cholinesterase Inhibitory Activity of a New Spiropyrrolidine Scaffold Tethered Benzo[b]Thiophene Analogue
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Enamine barbiturates and thiobarbiturates as a new class of bacterial urease inhibitors
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Synthesis, X-ray structure, Hirshfield analysis and DFT studies of a new Pd(II) complex with anionic s-triazine based NNO-donor ligand
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Synthesis and characterization of thiobarbituric acid enamine derivatives, and evaluation of their α-glucosidase inhibitory and anti-glycation activity
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New Spiroindolone Bearing Benzofuran Moiety as High Effective and Selective for COX-1 Inhibitor with TNF-α, and IL-6 inhibitory activity
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Expeditious green synthesis of novel 4-methyl-1,2,5,6-tetraazafluoranthen-3(2H)-one analogue from ninhydrin: N/S-alkylation and aza-Michael addition
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Discovery of hydrazide based pyridazino[4,5-b]indole scaffold as a new phosphoinositide 3-kinase (PI3K) inhibitors for breast cancer
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Regioselective Asymmetric Michael Addition Reaction Catalyzed by Soft Lewis Acid.
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Synthesis of Novel Class of Spiro Heterocycles via Dipolar Cycloaddition Reactions
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Synthesis and Biological Evaluation of Novel Pyrazolone Derivatives
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Preparation of new organic compounds using Aldol-Michael reaction
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Synthesis of some oxazole and imidazole derivatives and the study their chemical reactions and their pharmacological effectiveness and toxicity
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N-Acetyl Indole Linked to a Fused Triazolo/Thiadiazole Scaffold: Synthesis, Single Crystal X-Ray Structure, and Molecular Insight
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Structure, Antimicrobial Activity, Hirshfeld Analysis, and Docking Studies of Three Silver(I) Complexes-Based Pyridine Ligands
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Synthesis of N-(Anthracen-9-ylmethyl)-N-methyl-2-(phenylsulfonyl)ethanamine Via Microwave Green Synthesis Method: X-Ray Characterization, DFT and Hirshfeld Analysis
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Design, Construction, and Characterization of a New Regioisomer and Diastereomer Material Based on the Spirooxindole Scaffold Incorporating Sulphone Function
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Substituted spirooxindoles
Anti-cancer drug
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Alpha-Glucosidase Inhabitors
Alpha-Glucosidase Inhabitors
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Diethyl Ammonium Salts of Phenyl-Substituted Thiobarbituric Acid as Anti-Diabetic Agents
Anti-diabetic agent
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An efficient and green procedure for synthesis of rhodanine derivatives by aldol-thia-Michael protocol using aqueous diethylamine medium
A simple, economical, and green approach to the synthesis of rhodanine derivatives using a tandem aldol condensation-thia-Michael addition process in aqueous diethylamine medium was described. The experiment protocol features simple operations, and...
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A concise synthesis and evaluation of new malonamide derivatives as potential α-glucosidase inhibitors
A series of new malonamide derivatives were synthesized by Michael addition reaction ofN1,N3-di(pyridin-2-yl)malonamide into α,β-unsaturated ketones mediated by DBU in DCM at ambient temperature. The inhibitory potential of these compounds in vitro...
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Chemoenzymatic resolution of cis and trans 3,6-dihydroxy-α-ionone. Synthesis of the enantiomeric forms of dehydrovomifoliol and 8,9-dehydrotheaspirone
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Synthesis, olfactory evaluation, and determination the absolute configuration of the β- and γ-iralia®isomers
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