Iman Huessein Mohamed

Name   Iman Hussein Hasan
Date of Birth  3\ 1\ 1977
Academic Rank PhD of Biochemistry,
Chemistry/ Biochemistry Department
College of Science
Beni-Suef University
Mobile No.  00966/ 0559306915
E-mail   ihasan@ksu.edu.sa
                                    hesdn2001@yahoo.com

Education
July 2016

Apr. 2006

Sep. 2001 PhD – Biochemistry, Faculty of Science, Beni-Suef University, Egypt.

MSc – Biochemistry, Faculty of Science, Alexandria University, Egypt.

BSc (Biochemistry/Chemistry), Faculty of Science, Cairo University, Egypt. (Grade: Very Good).

Workshop for Specific Technique:
 RNA isolation technique. King Saud University.
 Western Blotting King Saud University.
 Real Time Polymerase Chain Reaction (RT- PCR). Cairo-University.
 RNA extraction by TriZol reagent from tissues. King Saud University
 The Polymerase Chain Reaction (PCR) technique. King Saud University
 Agarose Gel Electrophoresis. King Saud University
 Cell Lysis and Protein Extraction. King Saud University
 Reverse Transcription for RNA. King Saud University
 The Function and Structure for Protein. King Saud University

Personal Skills
 Writing scientific research by good commensurate with the international publication and coordination Excellence
 Scientific Research and its lab. Parts (research studies), experimental animal treatment and written the scientific paper to publishing in international journals.
 Computer applications (Office Programs), Internet, Power point (Presentation), SPSS and Prism (data analysis and prepare the figures).
 Organizing Seminars and Co-ordination with Scientific Exhibitions.

Conferences
 The 4th International Conference on Fixed Combination in the Treatment of Hypertension, Dyslipidemia and Diabetes Mellitus. Title: Responses to Alpha-Lipoic Acid in a Rat Diabetic Model: Possible Mechanisms? 2012.

  The 6th European Congress of Pharmacology EPHAR, JULY, 17-20 GRANADA/ SPAIN. Title: Responses to Alpha-Lipoic Acid in a Rat Diabetic Model: Possible Mechanisms? 2012.

 Diabetes UK Professional Conference 2014; ACC Liverpool. Title: Fenofibrate attenuates diabetic nephropathy in experimental diabetic rat model via suppression of augmented TGFβ1/Smad3 Signaling pathway. 5 – 7 March 2014.

 ICE / ENDO 2014-16th International Congress of endocrinology & The Endocrine Society’s 96th Annual Meeting & Expo.  Congress location: Chicago, Illinois Title: Renoprotective effects of fenofibrate via modulation of LKB1-AMPK mRNA expression in a rat model of diabetic nephropathy Date: 21 - 24 June 2014.

 The European Atherosclerosis Society (EAS) 2015 Glasgow Title: Simvastatin prevents cardiac hypertrophy in a rat model via modulation of the JAK/STAT pathway. Date: 21st to 25th March 2015.

 The American Diabetes Association's (ADA): 75th Scientific Session, (June 5-9) 2015, at the Ernest N. Morial Convention Center in New Orleans, Louisiana. Title: Sitagliptin mediated nephropathy effect via JAK/STAT pathway in Streptozotocin - induced diabetes in rats. Nouf M. Al-Rasheed, Nawal M. Al-Rasheed, Maha A. Al-Amin, Iman H. Hasan, Hanaa N. Al-Ajmi. (June 5-9) 2015

 Poster presented at the ASCPT 2016 Annual Meeting, In The American Society for clinical pharmacology and therapeutics (March 8-12, 2016) at the Hilton Bayfront in San Diego, CA. Title: Metformin alone or in Combination with Vitamin E Attenuates Isoproterenol-Induced Cardiac Injury: Possible Mechanisms?. Nouf M. Al-Rasheed, Dana A. AL-Rabeeah, Heba S. AL-Barrak, Salma A. AL-Salman, Shahd A. Ibrahim, Sulafa A. AL-Hassab, Nawal M. Al-Rasheed, Maha A. Al-Amin, Iman H. Hasan and Hanaa N. Al-Ajmi. March 8-12, 2016

Scientific Membership
Reviewer:
 National Academy of Sciences, India Section B:Biological Sciences
 International Journal for Vitamin and Nutrition Research.
 Vascular Pharmacology
 Biomedical Journals
 Journal of Cell and Animal Biology
 Journal of Applied Pharmaceutical Science

Research Interests
 Cardiovascular Diabetology.
 Diabetes Drug Development.
 Molecular Mechanisms of Diabetes, Obesity and Cardiovascular Disorders.
 Drug induced toxicity.
 Nuclear Receptors.
 Natural Products.
 Oxidative stress/inflammation signalling pathways.

Lab techniques experienced

 Enzyme Linked Immunosorbent Assay (ELISA).
 Conventional and real time PCR.
 Western Blotting.
 Microbial cultures and sensitivity testing.
 Investigation, care and use of experimental laboratory animals.
 Spectrophotometric analysis.

Selected Publications:
1. Nawal M. Al-Rasheed, Nouf M. Al-Rasheed, Iman H. Hasan, Maha A. Al-Amin, Hanaa N. Al-Ajmi, Raeesa A. Mohamad, and Ayman M. Mahmoud. Simvastatin Ameliorates Diabetic Cardiomyopathy by Attenuating Oxidative Stress and Inflammation in Rats. Oxidative Medicine and Cellular Longevity. Volume 2017, Article ID 1092015, 13 pages

2. Nouf Al-Rasheed, Laila M. Faddah, Iman H. Hasan, Hanaa M. Ali, Nawal Al-Rasheed, Nagla F. El Oraby, Mahmoud H. Mohamed, Amelioration of Panadol-induced Nephrotoxicity via Down-regulation of Bax/Bcl2 Ratio with Some Antioxidants. j.pharep.2017.04.019.

3. Nouf M. Al-Rasheed, Laila Fadda, Iman H. Hasan, Hanaa M. Ali, Nawal M. Al-Rasheed1, Musaed Al-Fayez, Raeesa A. Mohamad. Hepatoprotective Role of α-Lipoic acid and Thymoquinone in Acetaminophen- Induced Liver Injury: Down-Regulation of COX-2 and flt-1 Expression. Braz. Arch. Biol. Technol. v.59: e160703 Jan/Dec 2016

4. Laila M. Fadda, Nouf M. Al-Rasheed, Iman H. Hasan, Hanaa M. Ali, Nawal M. Al-Rasheed, Musaed Al-Fayez, Aly M. Ahmed, Nada Almutlaq, Nehal Qasem1 and Reem Khalaf. Bax and CD68 Expression in Response to Liver Injury Induced by Acetaminophen: The Hepatoprotective Role of Thymoquinone and Curcumin, Pakistan J. Zool., vol. 49(x), pp xxx-xxx, 2017. DOI: http://dx.doi.org/10.17582/journal.pjz/2016
 
5. Nouf M Al-Rasheed, Nawal M Al-Rasheed, Iman H Hasan, Maha AAl-Amin, Hanaa NAl-Ajmi, Ayman M Mahmoud. Sitagliptin attenuates cardiomyopathy by modulating the JAK/STAT signaling pathway in experimental diabetic rats. Drug Design, Development and Therapy 2016: 10 2095–2107.

6. Nouf Al‑Rasheed, Laila Faddah, Nawal Al‑Rasheed, Yieldez A. Bassiouni, Iman H. Hasan, Ayman M. Mahmoud, Raeesa A. Mohamad, Hazar I. Yacoub. Protective Effects of Silymarin, Alone or in Combination with Chlorogenic Acid and/or Melatonin, Against Carbon Tetrachloride‑induced Hepatotoxicity. Pharmacognosy Magazine 2016:12:S337-45.

7. Nawal M. Al-Rasheed, Nouf M. Al-Rasheed, Maha Al-Amin, Iman H. Hasan, Hanaa Al-Ajmi and Raeesa  A. Mohammad. Fenofibrate attenuates diabetic nephropathy in experimental diabetic rat model via suppression of augmented TGFβ1/Smad3 Signaling pathway. Archives of physiology and Biochemistry.2016.

8. Iman H. Hasan,* M. A. El-Desouky, Ghada M. Abd el aziz, Walaa G. Hozayen. Protective effects of Zingiber officinale against carbon tetrachloride induced liver fibrosis. IJPPS 9649 2015

9. Marwa M Al-Samhari, Nouf M Al-Rasheed, Salim Al-Rejaie, Nawal M Al-Rasheed, Iman H Hasan, Ayman M Mahmoud, and Nduna Dzimiri. Possible involvement of the JAK/STAT signaling pathway in N-acetylcysteine-mediated antidepressant-like effects. Exp Biol Med (Maywood) OnlineFirst, published on December 6, 2015 as doi: 10.1177/1535370215619707.

10. Iman H. Hasan,* M.A.El-Desouky, Walaa G. Hozayen, Ghada M. Abd el aziz . Protective effect of Zingiber officinale against CCl4-induced liver fibrosis is mediated through downregulating the TGF-β1/Smad3 and NF-κB/IκB pathways. Pharmacology, DOI (10.1159/000441229)/ 2015.

11. Nouf M. Al-Rasheed, Maha M. Al-Oteibi, Reem Z. Al-Manee, Sarah A. Al-Shareef, Nawal M. Al-Rasheed, Iman H. Hasan, Raeesa A. Mohamad , Ayman M. Mahmoud.  Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK/STAT pathway. Drug Design, Development and Therapy 2015.

12. Nawal M. Al-Rasheed1, Nouf  M. AL-Rasheed,  Hala A. Attia,  Maha A. Al-Amin, Iman H.Hasan, Hanaa N. Al-Ajmi, Raeesa A. Mohamad and Nasr A. Sinjilawi. Renoprotective effects of fenofibrate via modulation of LKB1-AMPK mRNA expression in a rat model of diabetic nephropathy. Pharmacology 2015.

13. Nouf M. AL-Rasheeda, Nawal M. Al-Rasheeda, Yieldez A. Bassiouni, Iman H. Hasana*, Maha Al-Amin and Hanaa Al-Ajmi. Vitamin D attenuates pro-inflammatory TNF-α cytokine expression by inhibiting NF- кB signalling in the hearts of rats with isoproterenol-induced cardiac hypertrophy. J Physiol Biochem (2015) 71:289–299.

14. Nawal M. Al-Rasheed, Nouf M. Al-Rasheed, Nayira A. Abdel Baky, Laila M. Faddah, Amal J. Fatani and Iman H. Hasan*. Prophylactic role of α-lipoic acid and vitamin E against zinc oxide nanoparticles induced metabolic and immune disorders in rats’ liver. European Review for Medical and Pharmacological Sciences, 18: 1813-1828, 2014.

15. Nawal M AL-Rasheed1, Nouf M AL-Rasheed1, MA AL-Amin1, AA Eissa1, HN AL-Ajmi1, IH Hasan. The Effects of Rosiglitazone on Isoproterenol-Induced Myocardial Infarction in Rats. International Journal of Pharmacology, 9(1); 80-85, 2013.

16. Nouf M. AL-Rasheed & Nawal M. Al-Rasheed & Hala A. Attia & Iman H. Hasan* & Maha Al-Amin & Hanaa Al-Ajmi & Raeesa A. Mohamad. Adverse cardiac responses to alpha-lipoic acid in a rat-diabetic model: possible mechanisms? J Physiol Biochem 69:761–778, (2013).

Accepted paper
17. Nouf Al-Rasheed, Laila M. Faddah, Iman H. Hasan, Hanaa M. Ali, Nawal Al-Rasheed, Hepatoprotective Role of α-Lipoic acid and Thymoquinone in Acetaminophen- Induced Liver Injury:  Down-Regulation of COX-2 and flt -1 Expression. Accepted in Braz. Arch. Biol. Technol (2016).

Articles under review

1. Protective effects of dipeptidyl peptidase-IV (DPP-IV) on myocardial injury and cardiac function in a diabetic rat model
2. Thymoquinone, Curcumin and α-Lipoic acid Combinations Attenuate Renal Complications in Panadol-Induced Nephrotoxicity via Multiple Mechanisms (Toxicology Mechanism and Methods)
3. Down Regulation of JAK, COX1 and COX2 protein expressions by some antioxidants in N-acetyl p-aminophenol –induced nephropathy (J Physiol Biochem )
4. Cardiac protective mechanism in STZ-diabetic rats by regulation of apoptotic pathways. (Cardiac failure)
5. Role of some natural anti-oxidants in the Down regulation of TLR4, LIPOCALINE and VCAM protein expression in NaF induced acute kidney injury
6. Molecular and Histopathological Study on the Ameliorative Effects of Curcumin  and Vitamin C Against Lead Acetate-Induced Hepatotoxicity in Wistar Rats

 

 

المؤهلات العلمية

الجامعة: 
Cairo University
من تاريخ: 
الثلاثاء, كانون الثاني (يناير) 2, 1996
إلى تاريخ: 
الخميس, تموز (يوليو) 1, 1999
التخصص: 
SCIENCE/ BIOCHEMISTRY
الدرجة العلمية: 
Bsc
وصف المؤهل: 
الجامعة: 
ALEXANDRIA UNIVERSITY
من تاريخ: 
السبت, أيلول (سبتمبر) 1, 2001
إلى تاريخ: 
الأربعاء, نيسان (أبريل) 12, 2006
التخصص: 
SCIENCE/ BIOCHEMISTRY
الدرجة العلمية: 
MASTER
وصف المؤهل: 
الجامعة: 
Bani-Suef University
من تاريخ: 
الاثنين, كانون الثاني (يناير) 7, 2013
إلى تاريخ: 
الخميس, تموز (يوليو) 7, 2016
التخصص: 
Biochemistry
الدرجة العلمية: 
PhD
وصف المؤهل: 
الجامعة: 
Bani-suef University
من تاريخ: 
الأربعاء, تشرين اﻷول (أكتوبر) 3, 2018
إلى تاريخ: 
الأربعاء, حزيران (يونيو) 7, 2017
التخصص: 
Quality Control
الدرجة العلمية: 
Diplomatic
وصف المؤهل: 
دبلومة رقابه الجودة
ملف مرفق: 
المرفقالحجم
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