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SAUD A ALARIFI

Professor

Cell and Molecular Biology, Zoology Department

كلية العلوم
Building 5 AB 98
publication
Journal Article
2014

Sensitivity of freshwater pulmonate snail Lymnaea luteola L., to silver nanoparticles

Toxicity of nanoparticles depends on many factors including size, shape, chemical composition, surface area and surface charge. Silver nanoparticles (AgNPs) are likely to enter the aquatic ecosystems because of their multiple applications and pose a health concern for humans and aquatic species. Therefore, we used a freshwater snail Lymnaea luteola L (L. luteola) to investigate the acute toxicity and genotoxicity of AgNPs in a static-renewal system for 96 h. AgNPs caused molluscicidal activity in L. luteola, with 96-h median lethal concentrations (LC50) (48.10 μg L(-1)). We have observed that AgNPs (36 μg L(-1)) elicited a significant (p<0.01) reduction in glutathione, glutathione-s-transferase and glutathione peroxidase with a concomitant increase in malondialdehyde level and catalase in digestive gland of L. luteola. However, a significant (p<0.01) induction in DNA damage was observed by the alkaline single cell gel electrophoresis in digestive gland cells treated with AgNPs for 24 and 96 h. These results demonstrate that silver nanoparticles are lethal to freshwater snail L. luteola. The oxidative stress biomarkers and comet assay can successfully be used as sensitive tools of aquatic pollution biomonitoring.

Publication Work Type
research article
Volume Number
104
Magazine \ Newspaper
Chemosphere .
Pages
134-40
more of publication
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The goal of this research is to create a novel Schiff base of chitosan polymer derivatives 1a-1j. Nanotechnology is a promising field since it avoids the usage of hazardous chemicals while also…

by Ponnusamy Packialakshmi, Perumal Gobinath, Daoud Ali, Saud Alarifi, Balasubramani Ravindran, Akbar Idhayadhulla, and Radhakrishnan Surendrakumar.
2021
publications

Objective

by Sundaram Thanigaivel, Agaram Sundaram Vickram, Vinayagam Saranya, Huma Ali, Saud Alarifi, Jeevan Kumar Reddy Modigunta, Krishnan Anbarasu, Rajasekhar Lakshmipathy, Karunakaran Rohini.
2022
publications

Zinc and its derivatives requirement increased to enhance human immunity against the different pandemics, including covid-19. Green synthesis is an emerging field of research. Zinc oxide (ZnO)…

by Natesan Vijayakumar, Venkataesan Kumari, Bhuvaneshwari Gandhimathi, Kaliyamoorthi Ayyadurai, Rajendran Jayaprakash, Kasi Gopinath, Marcello Nicoletti, Saud Alarifi, AND Marimuthu Govindarajan.
2021