SNPs in FNDC5 (irisin) are associated with protection from obesity and modulation of glucose and lipid metabolism
, Nasser M. Al-Daghri, Abdul Khader Mohammed, Omar S. Al-Attas, Osama E. Amer, Mario Clerici, Amal Alenad & Majed S. Alokail . 2016
Irisin is a recently identified myokine that plays an important role in preventing obesity and insulin resistance. We investigated whether the common FNDC5 (irisin precursor) gene variants influence susceptibility to obesity and type 2 diabetes (T2D) and verified the impact of FNDC5 gene variants on serum irisin levels, glucose and lipid metabolism in a Saudi population.
Publication Work Type
PHD
Magazine \ Newspaper
The FASEB Journal
Abstract
Objectives: To assess circulating fetuin A and fetuin B levels in participants with and without Gestational Diabetes Mellitus (GDM) and to find out their correlations with other…