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Apurinic/apyrimidinic endonuclease-1/redox effector factor-1 (APE-1) is a critical component of base excision repair that excises abasic lesions created enzymatically by the action of DNA…
Multiple myeloma (MM) is an uncontrolled differentiation of plasma B cells and the deposits in the bone marrow. MM accounts for 10% of blood cancers and nearly more than 22,000 new cases are…
Cannabinoid receptors have gained increasing attention as drug targets for developing potential therapeutic ligands. Here, we report the discovery and optimization of triaryl sulfonamides as a…
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The course is designed to provide the students with the essential fundamentals of medicinal chemistry. The course is focused on the physicochemical properties of drug molecules and the effects…
PHC 428 Medicinal Chemistry IV Number of credits: 2 + 1 Level: 9 Prerequisites: PHC 313 Course Description…