Improved Straightforward Chemical Synthesis of Dihydroxyacetone Phosphate through Enzymatic Desymmetrization of 2,2-Dimethoxypropane-1,3-diol

Switching from (R)- to (S)-selective chemoenzymatic DKR of amines involving sulfanyl radical-mediated racemization

Chemoenzymatic dynamic kinetic resolution (DKR) of amines involving sulfanyl radical-induced racemization happened to be the very first switchable DKR process allowing the…

by Lahssen ElBlidi, Nicolas Vanthuyne, Didier Siri, Stephane Gastaldi, Michele P. Bertrand, Gerard Gil

2010

En Route to (S)-Selective Chemoenzymatic Dynamic Kinetic Resolution of Aliphatic Amines. One-Pot KR/Racemization/KR Sequence Leading to (S)-Amides

by Michele P. Bertrand, Gerard Gil, Stephane Gastaldi, Nicolas Vanthuyne, Malek Nechab, Lahssen El Blidi

2009

Fructose-1,6-Bisphosphate Aldolase-Mediated Synthesis of Aminocyclitols (Analogues of Valiolamine) and their Evaluation as Glycosidase Inhibitors

A highly stereoselective method for the preparation of nitro and aminocyclitols, using fructose-1,6-bisphosphate aldolase, which catalyzes the aldol reaction of dihydroxyacetone phosphate (DHAP)…

by Lahssen ElBlidi, Flora Camps Bres, Zeinab Assaf, Henri Veschambre, Vincent Théry, Jean Bolte, Marielle Lemaire

2009

lahssen elblidi

Improved Straightforward Chemical Synthesis of Dihydroxyacetone Phosphate through Enzymatic Desymmetrization of 2,2-Dimethoxypropane-1,3-diol