User Image

Muhammad Farooq khan

Associate Professor

Associate professor of Cell and molecular Biology

كلية العلوم
College of Science, building S5 Lab # 1B44 (zebrafish lab)

4675783
fmuhammad
cv

CV

Bio
I was graduated from NWFP agricultural university peshawar Pakistan in 1996 with Animal sciences as major. I got my Master and PhD degrees from Kyungpook National university South Korea in 2000 and 2003 in medicine major in molecular Biology. I worked in National university of Singapore for 6 years and senior research fellow and then joined BZU university Pakistan as an Assistant professor for one year before joining King Saud University as an Assistant professor in 2008.
My research interests are to design and test natural and synthesized small anti angiogenesis molecules to be used as an effective anticancer therapy. Moreover, i am also interested to find out the molecular mechanism of angiogenesis during the development of an embryos using zebrafisb as model organism.
CV Text

 

CURRICULUM VITAE

 

 

 

 

Name:                                     Dr. Muhammad Farooq

Date of Birth:                         25-12-1969

Nationality                             Pakistani

 

Contact Details                     Associate professor,

Department of Zoology, College of Science, King Saud University, PO Box 2455 Riyadh, 11451Kingdom of Saudi Arabia

 

Email:  fmuhammad@ksu.edu.sa farooqpk69@gmail.com

 

 

Education and career

 

Academic Qualifications:

2000- 2003                             Ph.D. (Molecular Biology/Biomedical Sciences)

                                                School of Medicine, Department of Immunology, Kyungpook                         National University,     Deagu, South Korea.

 

1998-2000                              M.Sc. (Molecular Biology/Biomedical Sciences)

School of Medicine, Department of Immunology, Kyungpook National University, Deagu, South Korea.

 

1992-1996                              B.Sc. (Animal Husbandry)

N.W.F.P. Agricultural University, Peshawar, Pakistan

 

 

Professional Career

30-03-2016- present              Associate Professor

Department of Zoology, College of Science, King Saud University,

Kingdom of Saudi Arabia

 

22-12- 2008- 29-03-2016     Assistant Professor

Department of Zoology, College of Science, King Saud University,

Kingdom of Saudi Arabia

 

 

 

Feb- 2007-Dec-2008             Assistant professor/Acting Director.

Institute of Biotechnology, Faculty of Science, Bah Uddin Zakariya, University, Punjab, Multan, Pakistan

 

01.-2- 2003- Feb- 2008      Senior Research Fellows.

Department of Biological Sciences, Faculty of Science, National

University of Singapore, Singapore.

 

2000-2003                              Graduate student and Researcher

Trichogene, Department of Immunology, School of medicine, Kyungpook National University, Daegu, South Korea

 

Subject Matter Specialist (Animal Production and Health)

1996-1997                              Baluchistan Rural Support Program, (funded by GTZ Germany), Quetta, Pakistan

 

 

Research interests

 

  1. Investigating the molecular mechanism of rare human genetic diseases found in Saudi population by modeling genetic diseases in Zebrafish embryos.
  2. To study the mechanism of epigenetic regulation histone deacetylases (HDAC) in disease and development special focus on liver and brain cancers.
  3. To study the role of angiogenesis in solid tumors proliferation and metastasis and fishing novel natural angiogenic inhibitors from Arab flora and Arab traditional medicine.
  4. Design and study new class of HDAC inhibitors as potent anti-cancer molecules with minimum toxicities.
  5. Investigating the potential of Saudi traditional medicine and herbs as anti-cancer therapeutics using zebrafish and various human cancer cell lines. 

 

 

Academic supervisor for graduate studies

Currently supervising two PhD student, as main and co supervisor. One PhD and two MSc students have completed the thesis under my supervision.

Mentor for one PhD student, and two Hons student department of Biological science, National University of Singapore

Co-supervisor for three Hons project students in the Department of Zoology, College of Sciences, King Saud University.

Main supervisor for two MSc students and co-supervisor for two MSc in the institute of Biotechnology, Faculty of Science, Bah Uddin Zakariya, University, Punjab, Multan, Pakistan

Administrative Experience

Director Institute of Biotechnology, Bah Uddin Zakariya, University, Punjab, Pakistan (Feb to December 2008).

 

Membership in research or administrative committees

  1. Member of the Curriculum design committee for the Joint Bachelor program in Natural products, College of Science, King Saud University.
  2. Member of the Postgraduates and Research Committee in the Department of Zoology, King Saud University since 2016.
  3. Member of the Accreditation Committee (Sub-Committee) Department of Zoology, King Saud University since 2016.
  4. Member of Quality assurance and development committee 2023

 

Reviewer in following international peer-reviewed journal

 

  1. Drug Design, Development and Therapy
  2. Plos One
  3. Cancer Management and Research
  4. Journal of Hepatocellular Carcinoma
  5. OncoTargets and Therapy
  6. Cellular Physiology and Biochemistry
  7. Epigenomics
  8. Natural product research
  9. Natural Product communications
  10. Neurotoxicology and Teratology
  11. Chemico-Biological Interactions
  12. Anti-Cancer Agents in Medicinal Chemistry
  13. BMC Complementary and Alternative Medicine
  14. Current Bioactive Compounds
  15. Clinical Medical Reviews and Case reports
  16. Journal of Aquaculture Research & Development
  17. Journal of Marine Science & Research Development
  18. Journal of Environmental & Analytical Toxicology
  19. Journal of Experimental Pharmacology
  20. Environmental Risk Assessment and Remediation
  21. Cancers
  22. Molecules
  23. International journal of molecular medicine
  24. Molecular nutrition
  25. Frontier in development and cell biology
  26. Frontier in immunology
  27. Heliyon

 

Board member in Scientific Journals

  1. Pak Euro Journal of Medical and life Sciences (editorial board member)
  2. Natural Product communication (reviewer board member)

 

 

 

 

Research Grants

             

project Title

Role

Duration

Funding Agency

Amount in SAR

status  

09-BIO888-02

 

Fishing of HDAC1 and HDAC3 interacting proteins from human liver cancer cell lines and zebrafish embryos by using Tandem Affinity Purification (TAP- tagging) and affinity based protein tagging technologies

PI

Two years

National plan for Science and technology (KACST)

~2 million

completed

G1107-389-NPST-BIO-Farooq

Bioactivity guided isolation of anti-angiogenic natural products using zebrafish as drug screening model

PI

Two years

National plan for Science and technology (NPST –KACST)

Around 2 million

Completed

SCI-30-12

Seasonal determination of Bio-accumulation of heavy metals in the local species of gastropods  (marine snails) from coastal area of Kingdom of Saudi Arabia

 

Principle investigator

One year

Sabic company

45,000

completed

DRI-KSU-

659.

Genetic changes in fish and shellfish as a result of anthropogenic activities in the Arabian Gulf and Red Sea, Kingdom of Saudi Arabia.

Co- investigator

Three years

International collaboration program, Ministry of Education, Kingdom of Saudi Arabia

Around 2 million

ongoing

 

 

h-Index 21 (https://www.webofscience.com/wos/author/record/G-9838-2013)

Top 2% highly cited researchers Stanford University 2021

Publication   

  1. Khan MF, Alanazi RF, Baabbad AA, Almoutiri ND, Wadaan MA. Angiogenic protein profiling, phytochemical screening and in silico anti-cancer targets validation of stem, leaves, fruit, and seeds of Calotropis procera in human liver and breast cancer cell lines. Environ Res. 2024;256:119180.
  2. Abbasi BHA, Rashid N, Bilal RM, Wadaan MA, Khan MF. Supplementation of Cichorium intybus roots improved the growth performance, immunity response, gut ecology and morphology of broilers chicken Ross308 strain. Journal of King Saud University - Science. 2024;36(8):103314.
  3. Ullah S, Khan SUH, Khan MF, Khattak B, Fozia F, Ahmad I, et al. Multiple-Drug Resistant Shiga Toxin-Producing E. coli in Raw Milk of Dairy Bovine. Trop Med Infect Dis. 2024;9(3).
  4. Shamsa Hilal Saleh Alanazi , Muhammad Farooq Khan , Anas M. Alazami , Almohannad Baabbad , Mohammad Ahmed Wadaan. Calotropis procera: A double edged sword against  glioblastoma, inhibiting glioblastoma cell line growth by targeting histone deacetylases (HDAC) and angiogenesis. Volume 10, Issue 2, 30 January 2024, e24406

 

  1. Muhammad Farooq Khan, Asma Mhd Youhia Charbaji, Almohannad A.Baabbad, Nawaf D. Almoutiri, Mohammed A. M. Wadaan. Investigating the role of Cinnamomum verum in zebrafish swim bladder development and anti-cancer activity in human lung cancer cell lines  Arabian Journal of Chemistry, Volume 16, Issue 12,2023,105361

 

  1. Mohammad Ahmad Wadaan, Almohannad Baabbad, Muhammad Farooq Khan Assessment of antidiabetic, anti-inflammatory, antioxidant and anticancer activity competence of methonolic extracts of Trianthema ortulacastrum and Andrographis paniculate. Environmental Research 242 (2024) 117764.

 

  1. Mohammad Ahmad Wadaan , Almohannad Baabbad , Muhammad Farooq Khan, Mythili Saravanan, A. Anderson. Phytochemical profiling, anti-hyperglycemic, antifungal, and radicals scavenging potential of crude extracts of Athyrium asplenioides- an in-vitro approach Environmental Research 231 (2023) 116129.

 

  1. Mohammad Ahmad Wadaan , Almohannad Baabbad , Muhammad Farooq Khan, Rajasree Shanmuganathan,  Freedon Daniel. Phytotoxicity and cytotoxicity attributes of immobilized Bacillus cereus treated and untreated textile effluents on Vigna mungo seeds and Artemia franciscana larvae. Environmental Research 231 (2023) 11611.

 

  1. Kazi M, Khan MF, Nasr FA, Ahmed MZ, Alqahtani AS, Ali MM, Aldughaim MS. Development of Curcumin and Piperine-Loaded Bio-Active Self-Nanoemulsifying Drugs and Investigation of Their Bioactivity in Zebrafish Embryos and Human Hematological Cancer Cell Lines. Int J Nanomedicine. 2023 Apr 6;18:1793-1808

 

  1. Fahd A. Al-Mekhlafi, Nael Abutaha, Muhammad Farooq, Muhammad A. Wadaan, Mohammed S. Al-Khalifa. Laboratory evaluation of the effects of Portunus pelagicus extracts against Culex pipiens larvae and aquatic non-target organisms, Journal of King Saud University - Science, Volume 35, Issue 9, 2023, 102924

 

  1. Ahmad Wadaan, M.;  Baabbad, A.;  Farooq Khan, M.;  Shanmuganathan, R.; Daniel, F., Phytotoxicity and cytotoxicity attributes of immobilized Bacillus cereus treated and untreated textile effluents on Vigna mungo seeds and Artemia franciscana larvae. Environmental Research 2023, 231, 116111.

 

  1. Robert Selvam, D.;  Xavier, S.;  Kasinathan, P.;  Ahmad Wadaan, M.;  Farooq Khan, M.; Santha Kumar David, M., Causes of higher levels of stress among students in higher education who used eLearning platforms during the COVID-19 pandemic. Journal of King Saud University - Science 2023, 35 (4), 102653

 

  1. Alrefaei, A. F., M. F. Al-Mrshoud, A. M. Alotaibi, Z. Ahmad, M. Farooq, H. F. Albalawi, M. F. Albeshr, E. Alshehri, M. H. Almutairi and G. A. Pizzio (2023). "Molecular identification and phylogenetic analysis of cytochrome b gene from Garra tibanica an endogenous species from Saudi Arabia." Journal of King Saud University – Science 2023  35(1): 102390.
  2. Ali S. Alqahtani; Mostafa M. Ghorab; Fahd A. Nasr; Mohammad Z. Ahmed; Abdullah A. Al Mishari; Sabry M. Attia; Muhammad Farooq Khan Cytotoxicity of Newly Synthesized Quinazoline–Sulfonamide Derivatives in Human Leukemia Cell Lines and Their Effect on Hematopoiesis in Zebrafish Embryos. Int. J. Mol. Sci. 2022, 23(9), 4720

 

  1. Mohammed S. Aldughaim; Mana M Alshehri; Nouf Al-Yhya; Mohammad Ahmed Wadaan; Saleh Al-Ghamdi; Mahmoud M. Habibullah; Hani Alothaid; Muhammad Farooq Khan. Prefoldin proteins 2/6, and HMG20B are regulated by HDAC1, HDAC3 and are novel therapeutic and prognostic biomarkers in hepatocellular carcinoma. Journal of King Saud University - Science 2022, 34, 101812

 

  1. Shahid Mahboob, Zubair Ahmed, Muhammad Farooq Khan,  Promy Virik, N.Al-Mulhm, Almohannad A.A.Baabbad. Assessment of heavy metals pollution in seawater and sediments in the Arabian Gulf, near Dammam, Saudi Arabia. Journal of King Saud University – Science. Volume 34, Issue 1, January 2022, 101677

 

  1. Umair Muhammad, Farooq Khan Muhammad, Aldrees Mohammed, Nashabat Marwan, Alhamoudi Kheloud M., Bilal Muhammad, Alyafee Yusra, Al Tuwaijri Abeer, Aldarwish Manar, Al-Rumayyan Ahmed, Alkhalaf Hamad, Wadaan Mohammad A. M., Alfadhel Majid. Mutated VWA8 Is Associated With Developmental Delay, Microcephaly, and Scoliosis and Plays a Novel Role in Early Development and Skeletal Morphogenesis in Zebrafish  Frontiers in Cell and Developmental Biology Volume 9 , 2021, PAGES=2575.

 

  1. Raha Orfali, Shagufta Perveen, Muhammad F. Khan, Atallah F. Ahmed, Sobia Tabassum, Paolo Luciano, Giuseppina Chianese, Orazio Taglialatela-Scafati, Asporychalasin, a bioactive cytochalasan with an unprecedented 6/6/11 skeleton from the Red Sea sediment Aspergillus oryzae, Phytochemistry, Volume 192, 2021, 112952,

 

  1. Raha Orfali, Shagufta Perveen, Muhammad Farooq Khan, Mohammad Ahmed Alwadaan, Atallah F. Ah-med, Areej Al-Taweel, Ali S. Alqahtani, Fahad A. Nasr, Sobia Tabassum, Paolo Luciano, Giuseppina Chianese, Jyh-Horng Sheu, and Orazio Taglialatela-Scafati. Antiproliferative illudalane sesquiterpenes from the marine fungus Aspergillus oryzae. Has been accepted in Mar. Drugs (ISSN 1660-3397) on 07 June 2021

 

  1. Nouf Al-yhya, Muhammad Farooq Khan, Rafa Sharaf Almeer, Mana M Alshehri, Mohammed S. Aldughaim, Mohammad Ahmed Wadaan. Pharmacological inhibition of HDAC1/3-interacting proteins induced morphological changes, and hindered the cell proliferation and migration of hepatocellular carcinoma cells. Environ Sci Pollut Res (2021). https://doi.org/10.1007/s11356-021-13668-1

 

  1. Nael M. Abutaha, Muhammad Farooq, Mohammed AL-Zharani, Amal Alotaibi,Mary Anne W. Cordero, Asmatanzeem Bepari, Saud Alarifi. Cytotoxic activity and toxicity study of HF8, a poly-herbal formulation. Journal of King Saud University – Science 33 (2021) 101377
  2. Malebari, A.M.; Abd Alhameed, R.; Almarhoon, Z.; Farooq, M.; Wadaan, M.A.M.; Sharma, A.; de la Torre, B.G.; Albericio, F.; El-Faham, A. The Antiproliferative and Apoptotic Effect of a Novel Synthesized S-Triazine Dipeptide Series, and Toxicity Screening in Zebrafish Embryos. Molecules 2021, 26, 1170.
  3. Muhammad Farooq Khan, Nasr, F.A.; Noman, O.M.; Alyhya, N.A.; Ali, I.; Saoud, M.; Rennert, R.; Dube, M.; Hussain, W.; Green, I.R.; Basudan, O.A.M.; Ullah, R.; Anazi, S.H.; Hussain, H. Cichorins D–F: Three New Compounds from Cichorium intybus and Their Biological Effects. Molecules 2020, 25(18), 4160; 

 

  1.  Muhammad Farooq Khan, Ali S. Alqahtani, Omer M. Almarfadi, Riaz Ullah, Fahd A. Nasr, Omar M. Noman, Nasir A. Siddiqui, Abdelaaty A. Shahat, Syed Rizwan Ahamad. The Reproductive Toxicity Associated with Dodonaea viscosa, a Folk Medicinal Plant in Saudi Arabia. Evidence-Based Complementary And Alternative Medicine Volume: 2021, Article Number: 6689110 DOI: 10.1155/2021/6689110, Published: JAN 15 2021

 

  1. Attique Z, Ali A, Hamza M, Al-Ghanim KA, Mehmood A, Khan S, Ahmed Z, Al-Mulhm N, Rizwan M, Munir A, Al-Suliman E, Farooq M, F AM, Mahboob S. In-silico network-based analysis of drugs used against COVID-19: Human well-being study. Saudi J Biol Sci. 2021 Mar;28(3):2029-2039. doi: 10.1016/j.sjbs.2021.01.006.

 

  1. Iman Ali Alanazy, Badr aldahmash, Doaa Mohamed El-Nagar, Khalid Elfaki Ibrahim, Ahmed Mostafa Rady & Muhammad Farooq Khan. Melatonin abrogates liver, ovarian, and uterine toxicities induced by tamoxifen in a breast cancer mouse model. Indian Journal of Experimental Biology Vol. 59, January 2021, pp. 33-43
  2.  
  3. Farooq Khan, M.; Nasr, F.A.; Baabbad, A.A.; Alqahtani, A.S.; Wadaan, M.A.M. Investigating the Anticancer Activity and Characterization of Bioactive Constituents of Moricandia sinaica (Boiss.) Boiss through In Vitro and In Silico Approaches in Triple-Negative Breast Cancer Cell Line. Appl. Sci. 2021, 11, 1244.

 

  1. Ali S. Alqahtani, Rashed N. Herqash, Omar M. Noman, Fahd A. Nasr , Nouf Alyhya, Shamsa H. Anazi, Muhammad Farooq, and Riaz Ullah (2020)  In Vitro Antioxidant, Cytotoxic Activities, and Phenolic Profile of Senecio glaucus from Saudi Arabia. Evidence based complementary and alternative medicine Volume 2020 |Article ID 8875430 | https://doi.org/10.1155/2020/8875430

 

  1. Fahd A. Nasr, Omar M. Noman Ali  S.Alqahtani, Wajhul Qamar Syed Rizwan Ahamad Abdullah A.Al-Misharia, Nouf Alyhya, Muhammad Farooq (2020). Phytochemical constituents and anticancer activities of Tarchonanthus camphoratus essential oils grown in Saudi Arabia.  Saudi Pharmaceutical Journal Volume 28, Issue 11, November 2020, Pages 1474-1480

 

  1. Abdulrahman Mohammed Alotaibi,  ZubairAhmad,  Muhammad Farooq, Hmoud Fares Albalawi,  Abdul wahed  Fahad Alrefaei  (2020). Phylogenetic analysis of three endogenous species of fish from Saudi Arabia verified that Cyprinion acinaes hijazi is a sub-species of Cyprinion acinaces acinases. Journal of King Saud University – Science Volume 32, Issue 7, October 2020, Pages 3014-3017

 

  1. Muhammad Farooq, Fahad Ali Nasir, Nawaf D. Almoutiri , Nouf Al-yhya , Mohammad Ahmed Wadaan. The phytochemical screening and antiangiogenic activity of audthan- al-himar (Moricandia sinaica Boiss.) extracts in zebrafish embryos and human umbilical vein endothelial cells. Journal of King Saud University Science. 2020 Volume 32, Issue 4, June 2020, Pages 2370-2376
  2. Ayman El-Fahama,, Anamika Sharma , Muhammad Farooq , Zainab Almarhoona , Rakia Abd Alhameed , Mohammad A.M. Wadaand, Beatriz G. de la Torre  , Fernando Albericio. Protocol for synthesis of di- and tri-substituted s-triazine derivatives. MethodsX 7 Volume 7, 2020, 100825
  3. Muhammad Farooq, Nael Abutaha, Shahid Mahboob, Almohannad Baabbad, Nawaf D. Almoutiri, Mohammad Ahmed A.M. Wadaan,(2019). Investigating the antiangiogenic potential of Rumex vesicarius (humeidh), anticancer activity in cancer cell lines and assessment of developmental toxicity in zebrafish embryos. Saudi Journal of Biological Sciences Volume 27, Issue 2, February 2020, Pages 611-622
  4. Ayman El-Faham, Muhammad Farooq, Zainab Almarhoon, Rakia Abd Alhameed, Mohammad A.M. Wadaan, Beatriz G. de la Torre, Fernando Albericio, (2019). Di- and tri-substituted s-triazine derivatives: Synthesis, characterization, anticancer activity in human breast-cancer cell lines, and developmental toxicity in zebrafish embryos,   Bioorganic Chemistry Volume 94, 2020
  5. Farooq, M., Sharma, A., Almarhoon, Z., Al-Dhfyan, A., El-Faham, A., Abu Taha, N., Wadaan, M. A. M., de la Torre, B. G., and Albericio, F. (2019) Design and synthesis of mono-and di-pyrazolyl-s-triazine derivatives, their anticancer profile in human cancer cell lines, and in vivo toxicity in zebrafish embryos. Bioorganic Chemistry 87, 457-464
  6. Muhammad Farooq, Nael Abu Taha, Fahd A. Nasr , Ali S. Al qahtani , Omar M. Noman and Mohammad Ahmed Mohammad Wadaan. (2019) Bitter Gourd (Momordica charantia) Possess Developmental Toxicity as Revealed by Screening the Seeds and Fruit extracts in Zebrafish Embryos. BMC complementary and alternative medicine 19(1):184. doi: 10.1186/s12906-019-2599-0.
  7. Elsayed Ahmed Elsayed, Mohammad Farooq, Mahmoud Sharaf-Eldin , Hesham Ali El-Enshasye, Mohammed Wadaan . Evaluation of neurotoxic and the developmental toxicity and anti-angiogenic potentials of essential seed oils from Moringa oleifera and Moringa peregrina seeds in zebrafish (Danio rerio) model. South African Journal of Botany. Volume 129, March 2020, Pages 229-237
  8. Iman Ali Al-Anazy; Badr Al-Dahmash; Doaa Mohamed El-Nagar; Khalid Elfaki Ibrahim; Jameel Al-Tamimi; Ahmed Moystafa Rady; Muhammad Farooq. (2020)  Hyper-ovulation, endometriosis, and hyperplasia associated with tamoxifen exposure in Swiss albino mice. Journal of King Saud University-Science. Volume 32, Issue 7, October 2020, Pages 3026-3031
  9. Farooq, M., Al Marhoon, Z. M., Abu Taha, N., Baabbad, A. A., Al-Wadaan, M. A., and El-Faham, A. (2018) Synthesis of Novel Class of N-Alkyl-isatin-3-iminobenzoic Acid Derivatives and Their Biological Activity in Zebrafish Embryos and Human Cancer Cell Lines. Biol Pharm Bull 41, 350-359
  10. Fahd A. Nasr, N. A., Mohammad Al-Zahrani, Muhammad Farooq,Mohammad A Wadaan. (2018) anticancer potential of plant extracts from riyadh (saudi arabia) on mda-mb-231 breast cancer cells African Journal of Traditional, Complementary and Alternative 15,  46-53
  11. Al-Mekhlafi, F. A., Abutaha, N., Farooq, M., and Al-Wadaan, M. (2018) Insecticidal effect of solenostemma argel extracts against culex pipiens. Journal of the American Mosquito Control Association 34, 217-223
  12. Abutaha, N., Al-Mekhlafi, F. A., Al-Keridis, L. A., Farooq, M., Nasr, F. A., and Al-Wadaan, M. (2018) Larvicidal potency of selected xerophytic plant extracts on Culex pipiens (Diptera: Culicidae). Entomological Research 48, 362-371
  13. Soliman, S. M., Albering, J. H., Farooq, M., Wadaan, M. A. M., and El-Faham, A. (2017) Synthesis, structural and biological studies of two new Co(III) complexes with tridentate hydrazone ligand derived from the antihypertensive drug hydralazine. Inorganica Chimica Acta 466, 16-29
  14. Elsayed, E. A., Farooq, M., Dailin, D., El-Enshasy, H. A., Othman, N. Z., Malek, R., Danial, E., and Wadaan, M. (2017) In vitro and in vivo biological screening of kefiran polysaccharide produced by Lactobacillus kefiranofaciens. Biomedical Research-India 28, 594-600
  15. Dongmo, C. T., Hussain, H., Boukeng, H. J. M., Saleem, M., Abbas, G., Farooq, M., Wadaan, M. A. M., Dongo, E., and Al-Harrasi, A. (2017) Ozoromide: A New Ceramide from the Stem Bark of Ozoroa pulcherrima. Chemistry of Natural Compounds 53, 923-925

 

  1. Hussain, B., Sultana, T., Sultana, S., Mahboob, S., Farooq, M., Al-Ghanim, K., and Nadeem, S. (2016) First report on fish cysteine as a biomarker of contamination in the River Chenab, Pakistan. Environmental Science and Pollution Research 23, 15495-15503

 

  1. Farooq, M., Abu Taha, N., Butorac, R. R., Evans, D. A., Elzatahry, A. A., Elsayed, E. A., Wadaan, M. A. M., Al-Deyab, S. S., and Cowley, A. H. (2015) Biological Screening of Newly Synthesized BIAN N-Heterocyclic Gold Carbene Complexes in Zebrafish Embryos. International Journal of Molecular Sciences 16, 24718-24731

 

  1. Farooq, M. (2015) Neuro-protective Activity of Pulicaria glutinosa in Oxidative Stress-induced Neurotoxicity in Zebrafish Embryos. International Journal of Agriculture and Biology 17, 193-198

 

  1. El-Faham, A., Farooq, M., Khattab, S. N., Abutaha, N., Wadaan, M. A., Ghabbour, H. A., and Fun, H. K. (2015) Synthesis, Characterization, and Anti-Cancer Activity of Some New N'-(2-Oxoindolin-3-ylidene)-2-propylpentane hydrazide-hydrazones Derivatives. Molecules 20, 14638-14655

 

  1. Abutaha, N., Mashaly, A. M. A., Farooq, M., and Wadaan, M. A. (2015) Apoptotic Potential of Artemsia sieberia Besser (Asteraceae) Fraction against Human Cancer Cell Lines. Tropical Journal of Pharmaceutical Research 14, 1779-1785

 

  1. Abutaha, N., Mashaly, A. M. A., Al-Mekhlafi, F. A., Farooq, M., Al-shami, M., and Wadaan, M. A. (2015) Larvicidal activity of endophytic fungal extract of Cochliobolus spicifer (Pleosporales: Pleosporaceae) on Aedes caspius and Culex pipiens (Diptera: Culicidae). Applied Entomology and Zoology 50, 405-414

 

  1. Muhammad Farooq, Wael N. Hozzein, Saber Z.S. Ahmed and Mohammed A.M. Wadaan. Cytotoxic Activities of Actinobacteria Isolated from the Saudi Habitats by the Brine Shrimp Lethality Assay. JOURNAL OF PURE & APPLIED MICROBIOLOGY, Nov. 2014. Vol. 8(Spl. Edn. 2), p. 791-795

 

  1. Mashaly, A. M. A., Farooq, M., Hozzein, W., Al-Qahtani, A. M., and Al-Mekhlafi, F. A. (2014) Assessment of toxic baits for the control of the samsum ant, Pachycondyla sennaarensis (Formicidae: Ponerinae). African Entomology 22, 204-209

 

  1. El-Faham, A., Farooq, M., Khattab, S. N., Elkayal, A. M., Ibrahim, M. F., Abutaha, N., Wadaan, M. A., and Hamed, E. A. (2014) Synthesis and Biological Activity of Schiff Base Series of Valproyl, N-Valproyl Glycinyl, and N-Valproyl-4-aminobenzoyl Hydrazide Derivatives. Chemical & Pharmaceutical Bulletin 62, 591-599

 

  1. Farooq, M., and Wadaan, M. A. M. (2013) Epigenetic targets in hepatocellular carcinoma cells: identification of chaperone protein complexes with histone deacetylases. Epigenomics 5, 501-512

 

  1. Farooq, M., Hozzein, W. N., Elsayed, E. A., Taha, N. A., and Wadaan, M. A. M. (2013) Identification of Histone Deacetylase 1 Protein Complexes in Liver Cancer Cells. Asian Pacific Journal of Cancer Prevention 14, 915-921

 

  1. Ahmad, M., Wadaan, M. A. M., Farooq, M., Daghestani, M. H., and Sami, A. S. (2013) Effectiveness of zinc in modulating perinatal effects of arsenic on the teratological effects in mice offspring. Biological Research 46, 131-138

 

  1. Mahboob, S., Farooq, M., Mahmood, S., Nasir, N., Sultana, S., Chaudhry, A. S., Al-Akel, A. S., Al-Balawi, H. F. A., Al-Misned, F., and Al-Ghanim, K. A. (2012) Phylogenetic relationship of cultured and wild labeo rohita and cirrhinus mrigala based on muscles proteins profile in different weight groups: a new tool in phylogenetic analysis. International Journal of Food Properties 15, 949-960

 

  1. Li, Y., Farooq, M., Sheng, D. L., Chandramouli, C., Lan, T., Mahajan, N. K., Kini, R. M., Hong, Y. H., Lisowsky, T., and Ge, R. W. (2012) Augmenter of Liver Regeneration (alr) Promotes Liver Outgrowth during Zebrafish Hepatogenesis. Plos One 7

 

  1. Farooq, M., El-Faham, A., Ahmad, M., Sami, A. S., and Wadaan, M. A. (2012) Teratogenic Profile of Valproic Acid and Newly Synthesized Derivatives in Zebrafish Embryos. International Journal of Agriculture and Biology 14, 894-900

 

  1. Ahmad, M., Elnakady, Y., Farooq, M., and Wadaan, M. (2011) Lithium Induced Toxicity in Rats: Blood Serum Chemistry, Antioxidative Enzymes in Red Blood Cells and Histopathological Studies. Biol Pharm Bull 34, 272-277

 

  1. Raghunath, M., Wong, Y. S., Farooq, M., and Ge, R. (2009) Pharmacologically induced angiogenesis in transgenic zebrafish. Biochemical and Biophysical Research Communications 378, 766-771

 

  1. Farooq, M., Sulochana, K. N., Pan, X. F., To, J. W., Sheng, D., Gong, Z. Y., and Ge, R. W. (2008) Histone deacetylase 3 (hdac3) is specifically required for liver development in zebrafish. Developmental Biology 317, 336-353

 

  1. Sung, Y. K., Hwang, S. Y., Park, M. K., Farooq, M., Han, I. S., Bae, H. I., Kim, J. C., and Kim, M. (2003) Glypican-3 is overexpressed in human hepatocellular carcinoma. Cancer Science 94, 259-262

 

  1. Sung, Y. K., Hwang, S. Y., Farooq, M., Kim, J. C., and Kim, M. K. (2003) Growth promotion of HepG2 hepatoma cells by antisense-mediated knockdown of glypican-3 is independent of insulin-like growth factor 2 signaling. Experimental and Molecular Medicine 35, 257-262

 

  1. Farooq, M., Hwang, S. Y., Park, M. K., Kim, J. C., Kim, M. K., and Sung, Y. K. (2003) Blocking endogenous glypican-3 expression releases Hep 3B cells from G1 arrest. Molecules and Cells 15, 356-360

 

  1. Chung, E. J., Sung, Y. K., Farooq, M., Kim, Y., Im, S., Tak, W. Y., Hwang, Y. J., Kim, Y. I., Han, H. S., Kim, J. C., and Kim, M. K. (2002) Gene expression profile analysis in human hepatocellular carcinoma by cDNA microarray. Molecules and Cells 14, 382-387

 

  1. Farooq, M., Kim, Y., Im, S., Chung, E., Hwang, S., Sohn, M., Kim, M., and Kim, J. (2001) Cloning of BNIP3h, a member of proapoptotic BNIP3 family genes. Experimental and Molecular Medicine 33, 169-173

 

Papers presented in Conferences/Workshop

 

  1. Shahid Mahboob Muhammad Farooq, Nael Abutaha, Mohannad Baabbad, Nawaf D. Almoutiri, Mohammad Ahmed A.M. Wadaan. ZEBRAFISH AS BIOACTIVITY GUIDED DRUG SCREENING ANIMAL MODEL TO IDENTIFY ANTIANGIOGENIC COMPOUNDS FROM SAUDI MEDICINAL PLANTS. Aquaculture America 2020

February 9 - 12, 2020 - Honolulu, Hawaii International Conference & Exposition.

  1. Muhammad Farooq. Paper Title: Phytochemical Screening and Antiangiogenic Activity of Saudi Medicinal Plants and Herbs: Whether Natural Anti-Angiogenic Products a Durable Cancer Therapy? The 7th International Conference on Chemical and Biological Sciences. (ICCBS 2020), Singapore during March 6-8, 2020.
  2. Muhammad Farooq, Sheng Donglai and Ruowen Ge.” Characterization of Hepatopoietin/ Augmenter of liver regeneration in zebrafish development” International workshop on fish genetics and development, Chinese Academy of Sciences, Wuhan China October 11-14, 2004
  3. Sheng Donglai, Muhammad Farooq and Ruowen Ge” Molecular cloning and functional characterization of Hepatocyte growth factor (HGF) and its receptor c-MET from zebrafish Danio rerio” International workshop on fish genetics and development, Chinese Academy of Sciences, Wuhan China October 11-14, 2004
  4. Muhammad Farooq and Ruowen Ge “Role of vascularization in the development of liver in  zebrafish”  6th  International  Conference  on  Zebrafish  Development  and  Genetics, university of Wisconsin Madison USA from July 29 to August 2, 2004
  5. Muhammad Farooq, KN Soluchana, Xiufang Pan, Donglai Sheng, Zhiyuan Gong and Ruowen Ge “Histone deacetylase (HDAC) inhibitors inhibit zebrafish embryonic angiogenesis and liver/pancreas formation and HDAC-3 plays a specific role in zebrafish liver/pancreas development “International conference "Combined Scientific Meeting (CSM) 04-06 November, 2005 Singapore
  6. Muhammad  Farooq  Vasculata  2004  a  summer  course  organized  by  University  of

Wisconsin, Seattle Washington from July 21- July 28, 2004

  1. Muhammad Farooq , Jiang Junhui ,  Mohammad A.Wadaan , Ge Ruowen Valproic acid induced lever defects in zebrafish embryos, a platform to identify genes involved in liver formation and development in zebrafish using microarray presented in 26th Saudi Biological Society meeting held in city of Taif, Kingdom of Saudi Arabia from 10-12 May 2011.
  2. Muhammad Farooq, Ayman Al  Faham,  ,  M.  Ahmed,  Nakady  Y.E,      M.  A. Wadaan. Valproic acid derivatives as inducer of notochord defects in developing zebrafish embryos, a model to study the notochord cells differentiation and regeneration presented in 26th Saudi Biological Society meeting held in city of Taif, Kingdom of Saudi Arabia from 10-12 May, 2011
  3. Muhammad Farooq and Mohammad A.Wadaan Thias savigny a potential bio-indicator for marine pollution presented in 26th Saudi Biological Society meeting held in city of Taif, Kingdom of Saudi Arabia from 10-12 May 2011.
  4. Muhammad Farooq, M. Abbas, M. A Wadaan Zebrafish embryos as drug screening model to screen anti-cancer candidate molecules using crude extracts from Saudi Arabian medicinal plants presented in 26th Saudi Biological Society meeting held in city of Taif, Kingdom of Saudi Arabia from 10-12 May 2011.
  5. Muhammad Farooq and Mohammad A. Wadaan Fishing HDAC1 and HDAC 3 interacting protein complexes by Tap Tag technology in Hep G2 cells Fifth Saudi Science Conference (SSC5'2012) April 16-18-2012  in Makkah Saudi Arabia
  6. Muhammad Farooq, Jiang Junhui, Ge Ruowen , Mohammed A. M. Wadaan. Knocking down HDAC family members in zebrafish, identified genes involved in liver formation in zebrafish. Presented in 4th World epigenetic summit conference held in United Kingdom, London from 4-6 December, 2012
  7. Muhammad Farooq, ElsayedA. Elsayed, Wael N.Hozzein, Nael A.Taha, Mohammad A.M. Wadaan. Proteomic identification of chaperon containing T complex protein 1 (TCP-1) proteins as interacting partner with HDAC1 and HDAC 3 in Liver cancer cells. Presented in 4th  World  epigenetic  summit  conference  held  in  United  Kingdom,  London,  from  4-6 December, 2012
  8. Muhammad Farooq Identification of Histone deacetylase interacting proteins via activity based protein profiling in liver cancer. Invited speaker International workshop organized by Thermo Fisher Scientific proteomic division (NAIZAK lab) in Holiday Inn Meydan Riyadh December 8, 2015.