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Assem Mahmoud El-Sayed Barakat

Professor

Professor

كلية العلوم
Department of Chemistry, Building No.5, Office: 2B-94; Lab: 2B-116 or 2B-84

+966114675901-75908
ambarakat@KSU.EDU.SA
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عاصم محمود السيد بركات

Bio
Assem Barakat, born in Egypt in 1981, earned a B.Sc. in Chemistry from Alexandria University in 2002. He commenced his career as a Chemist at Pharco Pharmaceutical Company before transitioning to the Chemistry Department at the College of Science, Alexandria University, through a government program for top-ranked students. In 2006, he received a one-year fellowship as a young researcher at the University of Genoa, Italy.

In 2007, Barakat was awarded a Ph.D. Scholarship program from Politecnico di Milano, Italy, in collaboration with ETH Zurich, Switzerland, and the University of Stuttgart, Germany, completing his degree in 2010. He joined Pharos University in Alexandria as a Lecturer of Organic Chemistry in 2010, subsequently moving to King Saud University in Riyadh, Saudi Arabia, as an Assistant Professor in 2011. He was later promoted to Associate Professor in 2017 and achieved the rank of full Professor in February 2021.

Barakat has received several awards, including the Arab Chemistry Award in 2016 (Saudi Chemical Society Scientific Excellence Award for the Youth Section) and the IAAM Scientist Award in 2020 in Ulrika, Sweden. His research interests encompass drug discovery, protein-protein interaction inhibitors (p53-MDM2), asymmetric synthesis, and X-ray single crystallography. He has authored over 300 articles and holds three patents. Additionally, he has supervised 13 Master's and four Ph.D. students to date.
CV Text

Personal profile

A confident, enthusiastic and hardworking chemist who is able to teach undergraduate and postgraduate students. Whilst at the same time, Barakat has a keen interest in professional development towards employment in the field of academic research.  Possessing extensive knowledge of research, developing, having immense subject knowledge, enthusiasm and charisma, as well as a genuine interest in educating others.

Profile Official Links

https://faculty.ksu.edu.sa/en/ambarakat

https://scholar.google.com/citations?hl=en&user=_6kVZ_IAAAAJ

https://orcid.org/0000-0002-7885-3201

https://www.scopus.com/authid/detail.uri?authorId=55773267300

https://loop.frontiersin.org/people/385770/overview

https://www.webofscience.com/wos/author/record/E-2071-2013

https://twitter.com/barakatassem?lang=en

https://www.facebook.com/assem.barakat

https://www.linkedin.com/in/assem-barakat-ab897451/

 

Education Profile

  1. Degrees Obtained:

2007- 2010

Ph.D. in Industrial Chemistry and Chemical Engineering ‘Organic Chemistry’ “ASYMMETRIC SYNTHESIS BY ENZYME AND SOFT LEWIS ACID CATALYSIS”. Politecnico di Milano, Milano, Italy.

Under Supervision of:

Prof. Dr. Claudio Fuganti (Retired), Dipartimento Di chimica, Materiali ed Ingegneria Chimica, Politecnico di Milano, Via Mancinelli 7, I-20131 Milano, Italy. claudio.fuganti@polimi.it

Prof.Dr. René Peters, Universität Stuttgart, Institut für Organische Chemie, Pfaffenwaldring 55, 70569 Stuttgart, Germany. rene.peters@oc.uni-stuttgart.de

2003-2004

Graduate courses in organic Chemistry. Department of Chemistry, Alexandria University, Alexandria, Egypt.

1998-2002

B.Sc. in Chemistry, Very good with honor. Department of Chemistry, Alexandria University, Alexandria, Egypt.
  1. Achievements/ Awards:
  • I have been listed in the 2%authors carrier list reported by Stanford University in 2020, 2021, 2023, 2024.
  • IAAM Scientist Award, 2020, Ulrika, Sweden.
  • Arab Chemistry Award 2016 (Saudi Chemical Society Scientific Excellence Award for Youth Section).
  • Fellowship for three years for Ph.D studies on 2007 by Institute of Politecnico di Milano, Milano, Italy.
  • Fellowship for one year for young researcher on 2006 at University of Genoa, Genoa, Italy.

Professional

 

Feb. 2021- Present

Professor of Organic Chemistry, College of Science, Chemistry Department, King Saud University.

Jan. 2017- Feb. 2021

Associate Professor of Organic Chemistry, College of Science, Chemistry Department, King Saud University.

Feb. 2011- Jan. 2017

Assistant Professor of Organic Chemistry, College of Science, Chemistry Department, King Saud University.

Sept. 2010-Jan. 2011

Lecturer of Organic Chemistry, Faculty of Pharmacy, Pharos University in Alexandria, Egypt.

Jan.2006-Dec.2006

Young researcher at University of Genoa, Genoa, Italy (Prof. G. Guanti and Prof. Luca Banfi).

Oct. 2003-Dec. 2005

Chemist at the Department of Chemistry, Alexandria University, Egypt.

April 2003-Oct. 2003

Pharco Pharmaceutical Company, Alexandria Egypt.

 

Visitor @

  • Visiting professor, University of Groningen, Drug design (Prof. Dr. Alexander Dömling) (24-5-2019 until 15/6/2019).
  • Department of Chemistry, Universität Stuttgart, Germany. Research group of Prof. René Peters. October 2008- October 2009.
  • ETH Zurich, Switzerland. Research group of Prof. René Peters. March–August 2008.

Member of:

  1. Member of American Chemical Society (31397115).
  2. Member of Saudi Chemical Society.
  3. Member of Egyptian Syndicate of Scientific professions.

Teaching Courses:

  1. Chemistry of Natural Products.                         
  2. Mechanism of Organic Reactions.                               
  3. General Organic Chemistry for Health Sciences. 
  4. Organic Chemistry.  
  5. Principles of organic chemistry I (Chemical Engineering students, College of Engineering).
  6. Heterocyclic chemistry
  7. Principles of organic chemistry II (Chemical Engineering students, College of Engineering).
  8. Advanced organic synthesis (PhD-student program).
  9. Advanced natural product (PhD-student program).

 

Professional activities

 

Participated in the department work for obtaining the Academic Accreditation for the undergraduate and postgraduate programs:

1. The international RE-accreditation from the German association for academic accreditation (ASIIN), 2017; under graduate program in chemistry (B.Sc.).

2- Accreditation from the National Commission for Academic Accreditation & Assessment (NCAAA), 2017; under graduate program in chemistry (B.Sc.).

3- Accreditation from the National Commission for Academic Accreditation & Assessment (NCAAA), 2018; post graduate programs in chemistry (M.Sc. & Ph.D).

 

Research Interests:

Areas of research interest and experience:

  • Design and synthesis of new entities as potential pharmaceuticals targets including (MDM2-p53 inhibitor; Phosphodiesterase 1; phosphoinositide 3-kinase (PI3K); HER2; Anti-Diabetics agents; COX-1 Inhibitor with TNF-α, and IL-6 inhibitory activity). COVID-19.
  • Development of new green synthetic methodologies for desired target molecule.
  • Development and synthesis of chiral reagents, metal catalysts in asymmetric synthesis to synthesize novel bioactive compounds.

Experimental and Technical Skills:

  • Development of some new synthetic methodologies.
  • Synthetic experience to work from milligram to gram scale
  • Expertise in column purification over silica and neutral alumina
  • Expertise in analysing spectroscopic data like FT-IR, (1H, 13C, 31P, 19F) NMR and Mass.
  • Preliminary training course how to solve the structure by X-ray crystallography using SHELXS97.
  • Identifying experimental problems and resolve them independently
  • Capable of both collaborative and independent research.
    • Knowledge of software:  SciFinder, MS-Office, Open Office, End Notes, ChemDraw-Ultra, ISIS Draw, Chem. Sketch, Chemwindow, Mass Frontier, Origin and their application to chemistry

Instruments handled:

  1. UV-Visible Spectrophotometer
  2. IR- Spectrophotometer
  3. Gas Chromatography
  4. High Performance liquid chromatography (HPLC)
  5. NMR

 

Research Fund

  • Deanship of Scientific Research at King Saud University for funding my research group project Number RGP- 257 (PI)
  • Deanship of Scientific Research at King Saud University for funding my research group project Number RGP-044. (Co-PI).
  • King Abdulaziz City for Science and Technology for financial support for Project No.: D-C-11-0050. (PI).
  • King Abdulaziz City for Science and Technology for financial support for Project No.: A-S-12-0017. (PI).
  • King Abdulaziz City for Science and Technology for financial support for Project No.: 1ط – 35 – 215. (PI).
  • NSTIP strategic technologies program, grant number 13-BIO1382-02(CO-PI).
  • NSTIP strategic technologies program, grant number 14-BIO128-02 (PI).
  • Dr. Sulaiman Al Habib Medical Services Group Company. (PI).
  • Researchers Supporting Projects (RSP-2019/64), (RSP-2020/64), and (RSP-2021/64), RSP-2022/64), RSP-2023/64), RSP-2024/64), King Saud University. (PI).

Publications

 

  1. S. Serra, A. Barakat, C.  Fuganti, Chemoenzymatic resolution of cis and trans 3,6-dihydroxy-α-ionone. Synthesis of the enantiomeric forms of dehydrovomifoliol and 8,9-dehydrotheaspirone, Tetrahedron: Asymmetry 2007, 18, 2573 – 2580.
  2. A.Barakat, E. Bernna, C. Fuganti, S. Serra, Synthesis, olfactory evaluation, and determination the absolute configuration of the β- and γ-iralia®isomers, Tetrahedron: Asymmetry2008, 18, 2316 – 2322.
  3. D. F. Fischer, A. Barakat, Z-q. Xin, M. E. Weiss, R. Peters, The asymmetric Aza-Claisen rearrangement: development of widely applicable pentaphenylferrocenyl palladacycle catalysts. Chem. Eur. J. 2009, 15, 8722 – 8741. (VIP article).*
  4. Y. N. Mabkhot, A. M. Al-Majid, A. Barakat, S. Alshahrani, Y. siddiqui, 1,1’-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as building block in heterocyclic synthesis. Novel synthesis of some pyrazoles, and pyrimidines derivatives. Molecules, 2011, 16(8), 6502-6511.
  5. Y. N. Mabkhot, A. Barakat, A.M. Al-Majid, Z. A. Al-Othman, A. S. Alamary, A Facile and convenient synthesis of some novel hydrazones, schiff’s base and pyrazoles incorporating thieno [2,3-b]thiophenes. Int. J. Mol. Sci. 2011, 12, 7824-7834.
  6. Y.N.  Mabkhot, A. Barakat, A.M. Al-Majid, and S.A. Alshahrani., Comprehensive and facile Synthesis of some functionalized bis-heterocyclic compounds containing a thieno[2,3-b]thiophene motif.  Int. J. Mol. Sci. 2012, 13, 2263-2275.
  7. M. A. Al-Majid, A. Barakat, Y. N. Mabkhot, M. S. Islam. Synthesis and characterization of privileged monodentate phosphoramidite ligands and chiral brønsted acid derived from D-mannitol. Int. J. Mol. Sci. 2012, 13, 2727-2743.
  8. M. A. Al Majid, M. S. Islam, Z. A. Al-Othman, A. Alslhob, A. Barakat. Synthesis of new C2symmetric chiral bisamide ligands derived from chiral Feist’s acid. Molecules, 2012, 17, 5550-5563.
  9. Y. N. Mabkhot, A. Barakat, A. M. Al-Majid, A. S. Alamary, Taleb T. Al-Nahary. A novel and expedient approach to new heterocycles containing thiazole, thiazolo[3,2-a]pyridine, dihydrothiophene, and hydrazonothieno[2,3-b]thiophene moieties. Int. J. Mol. Sci. 2012, 13, 5035-5047.
  10. A.Barakat, A.M. Al-Majid, Y. N. Mabkhot, and Z. A.Al-Othman. A practical chemo-enzymatic approach to highly enantio-enriched 10-ethyl-7,8-Dihydro-γ-ionone isomers. A method for the synthesis of 4,5-didehydro-α-ionone. Int. J. Mol. Sci. 2012, 13, 5542-5553.
  11. Y.N.Mabkhot, A. Barakat and S. Alshahrani, Expeditious and highly efficient protocol for the synthesis of novel diversely substituted thieno[2,3-b]thiophene. Journal of molecular structure 2012, 1027, 15–19.
  12. T. T. Al-Nahary, M. A. N. El-Ries, G. G. Mohamed, A. K. Attia, Y. N. Mabkhot, M. Harone, A. Barakat. Multiclass analysis on repaglinide, flubendazole, robenidine hydrochloride and danofloxacin drugs. Arabian Journal of Chemistry 2013, 6, 131–144.
  13. Y.N. Mabkhot, A. Barakat, A. M. Al-Majid, and M. Iqbal Choudhary. Synthesis of thieno [2, 3 -b] thiophene containing bis-heterocycles-novel pharmacophores. Int. J. Mol. Sci. 2013, 14(3), 5712-5722.
  14. Y.N. Mabkhot, A. Barakat, F. Alatibi, M. Iqbal Choudhary and S. Yousuf, (E)-Ethyl-5-(3-(dimethylamino)acryloyl)-4-phenyl-2-(phenylamino)thiophene-3-carboxylate, Acta Cryst,  2013, E69, o351.
  15. A.Barakat, Abdullah M. A. Al Majid, Mohammad Shahidul Islam, Zeid Abdullah Al-Othman. Highly enantioselective Friedel−Crafts alkylations of indoles with α,β-unsaturated ketones under Cu(II)-simple oxazoline-imidazoline catalysts. Tetrahedron, 2013, 69, 5185-5192.*
  16. A.Barakat, A. M. Al-Majid, Y. N. Mabkhot, S. S. Yousuf, M. Iqbal Choudhary, Dimethyl 2-(4-methylbenzylidene)malonate, Acta Cryst,  2013, E69, o919.
  17. Y.N. Mabkhot, F.Alatibi, A. Barakat, M. Iqbal Choudhary and Sammer S Yousuf. Ethyl-4-acetyl-3-methyl-5-(phenylamino)thiophene-2-carboxylate. Acta Cryst, 2013, E69, o1049.
  18. Y.N. Mabkhot, M. S. Al-Har and A.Barakat, Salim S. Al-Showiman, Diversity oriented design of various hydrazides and amides derived from isatoic anhydride and their antimicrobial activity evaluation. Digest Journal of Nanomaterials and Biostructures, 2013, 8, 1345 - 1355.
  19. Y. N. Mabkhot,  A. Barakat, A. M. A. Al Majid, , S.Alshahrani, S. Yousuf and M. I. Choudhary,  Synthesis, reactions and biological activity of some new bis-heterocyclic ring compounds containing sulphur atom. Chemistry Central Journal, 2013, 7, 112.
  20. Y. N. Mabkhot, S.S. Al-Showiman, A.Barakat, M. Iqbal Choudhary and S. Yousuf. 3,4-Dimethylthieno[2,3-b]thiophene-2,5-dicarbonitrile. Acta Cryst, 2013, E69, o1272.
  21. A.Barakat, M. Suleiman, B.Hammout, T. Ben Hadda, M. Al-Noaimi, S. F. Haddad, A. Boshaala, A.S.  Aldwayyan, I. Warad. One Step Synthesis of NiO Nanoparticles via Solid-state Thermal Decomposition at Low-Temperature of Novel Aqua-dmphen-NiCl2 Complex. Int. J. Mol. Sci. 2013, 14, 23941-23954.
  22. A.M. Al-Majid, A.Barakat, H. J. Al-Najjar, Y. N. Mabkhot, H. A. Ghabbour, H-K. Fun. Tandem Aldol-Michael reactions in aqueous diethylamine medium: A greener and efficient approach to bis-pyrimidine derivatives.  Int. J. Mol. Sci. 2013, 14, 23762-23773.
  23. A. Al Majid, M. Shahidul Islam, A. Barakat, M. H.M. Al-Agamy, Mu. Naushad. Facile and promising method for Michael addition of indole and pyrrole to electron deficient trans-β-nitroolefins catalyzed by Feist’s acid: Preliminary study of anti-microbial activity. The Scientific World Journal, 2014 (2014), Article ID 649197, 15 pages.
  24. M. Al-Majid, A. Barakat, and Y. N. Mabkhot, Facile and new convenient route for synthesis of some C2 symmetric bidentate phosphine ligands Derived from D- Mannitol. Journal of Saudi Chemical Society 2014, 18, 626-631.
  25. A.Barakat, A.M. Al-Majid, H. J. Al-Najjar, Y. N. Mabkhot, H. A. Ghabbour, H-K. Fun. An efficient and green procedure for synthesis of rhodanine derivatives by Aldol-thia-Michael protocol using aqueous diethylamine. RSC Adv., 2014, 4, 4909–4916.
  26. H. J. Al-Najjar, A.Barakat, A.M. Al-Majid,  Y. N. Mabkhot, M. Weber, H. A. Ghabbour, H-K. Fun. A greener and efficient approach to Michael addition of barbituric acid to nitroalkene in aqueous diethylamine medium. Molecules, 2014, 19, 1150-1162.
  27. Mohammad Shahidul Islam, A. M Al-Majid, Zeid A Al-Othman, A. Barakat. Highly Enantioselective Friedel-Crafts Alkylation of Indole with electron deficient trans-β-Nitroalkenes under simple Zn(II)-Oxazoline-Imidazoline Catalysts. Tetrahedron Asymmetry 2014, 25, 245–251.
  28. A.Barakat, A. M. Al-Majid, F. M. Al Qahatany, M. S. Islam, M. H.M. Al-Agamy. Synthesis, characterization and antimicrobial activity of novel pharmacophore incorporating imidazoline-oxazoline scaffold. Bulletin of the Korean Chemical Society, 2014, 35 (2), 562-568.
  29. Y.N. Mabkhot, A.M. Al-Majid, A. Barakat, M. Iqbal Choudhary, S.S Yousuf."1-(5-Acetyl-3,4-dimethyl-thieno[2,3-b]thiophen-2-yl)-ethanone. Z. Kristallogr. NCS 2014, 229, 39-40 / DOI 10.1515/ncrs-2014-0028.
  30. A.Barakat, A.M. Al-Majid, A. M. Al-Ghamdi, Y. N. Mabkhot, M. Rafiq Siddiqui, H. A. Ghabbour, H-K. Fun. Tandem Aldol-Michael reactions in aqueous diethylamine medium: A greener and efficient approach to dimedone-barbituric acid derivatives. Chemistry Central Journal, 2014, 8, 9.
  31. Y. N. Mabkhot, Abdullah M. Al-Majid, A.Barakat, Munirah S. Al-Har, S. Radi, M.M. Naseer and Taibi B., Synthesis and Biological Evaluation of 2-Aminobenzamide Derivatives as Antimicrobial Agents: Opening/Closing pharmacophore site.   Int. J. Mol. Sci.  2014, 15, 5115-5127.
  32. A.M. Al-Majid, A. Barakat, H. J. Al-Najjar, Y. N. Mabkhot, H. A. Ghabbour, H-K. Fun. Correction: Al-Majid, A.M., et al., Tandem Aldol-Michael Reactions in Aqueous Diethylamine Medium: A Greener and Efficient Approach to Bis-Pyrimidine Derivatives. Int. J. Mol. Sci. 2013, 14, 23762–23773. Int. J. Mol. Sci. 2014, 15, 7537-7538. 
  33. H. W. Darwish, A. Barakat, A. Nafady, M. Suleiman, M. Al-Noaimi, B. Hammouti, S. Radi, T.B. Hadda, A. Abu-Obaid, M.S. Mubarak, and I. Warad. Design, Synthesis, Characterization of Novel Ruthenium(II) Catalysts: Highly Efficient and Selective Hydrogenation of Cinnamaldehyde to (E)-3-Phenylprop-2-en-1-ol. Molecules, 2014, 19(5), 5965-5980.
  34. Y.N. Mabkhot, F.D. Aldawsari, S.S. Al-Showiman, A. Barakat, M. Iqbal Choudhary and S. Yousuf. Synthesis, Characterization, X-ray Crystal Structure and Anti-microbial activity  of 1,1'-(3,4-Diphenylthieno[2,3-b]thiophene-2,5- diyl)diethanone. Journal of Chemistry, 2014, 2014, Article ID 504860, 5pages. doi:10.1155/2014/504860.
  35. Y.N. Mabkhot, M. S. Al-Har, A. Barakat, F. D. Aldawsari, A. Aldalbahi, and Zaheer-Ul-Haq. Synthesis, Anti-microbial and Molecular Docking Studies of Quinazolin-4(3H)-one Derivatives. Molecules, 2014, 19(7) 8725-8739.
  36. A.Barakat, A. M. Al-Majid, H. J. Al-Najjar, Y.N.Mabkhot, S. Yousuf, and M. Iqbal Choudhary. Zwitterionic Pyrimidinium Adducts as Antioxidants with Therapeutic Potential for Nitric Oxide Scavenger. Eur. J.  Med. Chem. 2014, 84, 146–154. *
  37. A.Barakat, A.M. Al-Majid, Y.N. Mabkhot, H. A. Ghabbour, H-K. Fun. Crystal Structure of (E)-3-Mesityl-1-phenylprop-2-en-1-one. Zeitschrift für Kristallographie –NCS, 2014, 229, 235-236
  38. I. Warad, M. Azam, M. Asad, S.I. Al-Resayes, A.I. Asadi, W.D. Wanrosli, A. Barakat, S. Jodeh, A. Abu-Obid, M. Al-Noaimi. Cis-trans isomerism in Ru(II) complexes incorporating bis(diphenylphosphine) and diamine as co-ligands: Synthesis, Spectroscopic characterization and X-ray crystal structure of dichloromethane solvated cis-diamine bis(diphenylphosphinobutane)ruthenium(II) complex. Journal of molecular structure 2014, 1076, 724-729.
  39. A.Barakat, H.J. Al-Najjar, A.M. Al-Majid, S.F. Adil, M. Ali, V.H. Masand, H.A.Ghabbour, H-K. Fun. Synthesis, X-Ray diffraction, Thermogravimetric and DFT analyses of Pyrimidine Derivatives. Molecules. 2014, 19, 17187-17201.
  40. Y.N. Mabkhot, N.N.E. El-Sayed, F. Alatibi, A. Barakat, H. A Ghabbour and H-K.Fun. Synthesis, Characterization, and X-ray Crystal Structure of 3-Methyl-4-oxo-7-phenyl-4,7-dihydrothieno[2,3- b]pyridine -2-carboxyxlic acid ethyl ester. Asian Journal of Chemistry, 2014. Vol.26, No. 24, 8596-8598.
  41. A.Barakat, A.M. Al-Majid, H. J. Al-Najjar, M. Iqbal Choudhary, S.S Yousuf. Crystal Structure of 1,3-Dimethyl-5-(2,4,6-trimethylbenzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione. Zeitschrift für Kristallographie –NCS, 2014, 229, 269-270.
  42. Y.N. Mabkhot, A. Barakat, S. Yousuf, M. I. Choudhary, W. Frey, T. B. Hadda and M.S. Mubarak. Substituted thieno[2,3-b]thiophenes and related congeners: Synthesis, β-glucuronidase inhibition activity, crystal structure, and POM analyses. Bioorganic and Medicinal Chemistry, 2014, 22, 6715-6725.
  43. M. Al-Noaimi, H. W. Darwish, M. Suleiman, M. Abdoh, I. Saadeddin, S. Naveen, N. K. Lokanath, S. Radi, O. Bsharat, T. B. Hadda, A. Barakat, I. Warad. Synthesis, X-Ray Crystal Structure, Spectral, TG-DTA, Electrochemistry, and DNA Binding of [CoX2(dmdphphen)] (dmdphphen is 2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline,  X= Cl and NCS) Complexes. Bioinorganic Chemistry and Applications, 2014, 2014, Article ID 914241, 7 pages. http://dx.doi.org/10.1155/2014/914241.
  44. A.Barakat, A. M. Al-Majid, H. J. Al-Najjar, Saied M. Soliman, M. H.M. Al-Agamy, H.A Ghabbour and H-K. Fun. Synthesis, Molecular Structure Investigations and Antimicrobial Activity of 2-Thioxothiazolidin-4-one Derivatives. Journal of Molecular Structures 2015, 1081, 519–529.
  45. A.Barakat, H. J. Al-Najjar, A. M. Al-Majid, S. M. Soliman, Y. N. Mabkhot, H. A. Ghabbour, H-K. Fun. Synthesis, and Molecular characterization, of 5,5'-((2,4-dichlorophenyl)methylene)bis(1,3-dimethylpyrimidine 2,4,6(1H,3H,5H)-trione).  Journal of Molecular Structures 2015, 1084, 207-215.
  46. Y. N. Mabkhot, F. D. Aldawsari,Salim S. Al-Showiman, A. Barakat, T. Ben Hadda,  M. S. Mubarak, S. Naz , Z. Ul-Haq and Abdur Rauf.Synthesis, Bioactivity, Molecular Docking and POM Analyses of Novel Substituted Thieno[2,3-b]thiophenes and Related Congeners. Molecules, 2015, 20, 1824-1841.
  47. A.Barakat, Hany J. Al-Najjar, A. Mohammed Al-Majid, S.M. Soliman, Y. N. Mabkhot, M. Rafi Shaik, H. A. Ghabbour, H-K. Fun. Synthesis, NMR, FT-IR, X-ray structural characterization, DFT analysis and Isomerism aspects of 5-(2,6-dichlorobenzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione. Spectrochimica Acta.  2015, 147, 107-115.
  48. Y. Mabkhot, F. Aldawsari; S. Al-Showiman; A. Barakat; S. Soliman; M. Choudhary; S. Yousuf; M. Mubarak; T. Hadda. Novel Enaminone Derived From Thieno[2,3-b]thiene: Synthesis, X-Ray Crystal Structure, HOMO, LUMO, NBO Analyses and Biological Activity. Chemistry Central Journal, 2015, 2015, 9:24.
  49. M. S. Islam, A. Barakat, A. M. Al-Majid, S. Soliman, H. A. Ghabbour, Ching Kheng Quah.  H-K. Fun.  Synthesis, molecular structure and spectroscopic investigations of novel fluorinated spiro heterocycles. Molecules 2015, 20(5), 8223-8241.
  50. T.B. Hadda, Z.K. Genc, V. H. Masand, N. Nebbache, I.l Warad, S.Jodeh, M.Genc, Y. N. Mabkhot, A. Barakat, H. Salgado-Zamora. Computational POM and DFT Evaluation of Experimental in-vitro Cancer Inhibition of Staurosporine-Ruthenium(II) Complexes: The Power Force of Organometallics in Drug Design. Acta Chim. Slov. 2015, 62, 679–688.
  51. A.Barakat, A. M. Al-Majid, S.M. Soliman, Y. N. Mabkhot, M. Ali, H. A. Ghabbour, H-K. Fun, Abdul Wadood. Structural and spectral investigations of the recently synthesized chalcone (E)-3-mesityl-1-(naphthalen-2-yl) prop-2-en-1-one, a potential chemotherapeutic agent. Chemistry Central Journal, 2015, 9:35.
  52. Y. N. Mabkhot, N. A. Kaal, S. Alterary, S. S. Al-Showiman, A. Barakat, H. A. Ghabbour, W. Frey. Synthesis, In-vitro antibacterial, antifungal, and Molecular Modeling of Potent Anti-Microbial Agents from a Combined Pyrazole and Thiophene Pharmacophore. Molecules 2015, 20, 8712-8729.
  53. A.Barakat, A. M. Al-Majid, S. M. Soliman, M. Ali, Y. N. Mabkhot, H. A. Ghabbour, H-K. Fun. Molecular structure investigation and tautomerism aspects of (E)-3-benzylideneindolin-2-one. Journal of Chemical Sciences, 2015, 127(9)1547-1556.
  54. A.Barakat, S. M. Soliman, A. M. Al-Majid, G. lofty, H. A. Ghabbour, H-K. Fun, S.  Yousuf, M. I. Choudhary, Abdul Wadood. Synthesis and structure investigation of novel pyrimidine-2,4,6-trione  derivatives of highly potential biological activity as anti-diabetic agent. Journal of Molecular structure 2015, 1098, 365-376.
  55. A.Barakat, H.A. Ghabbour, A. M. Al-Majid, S. M. Soliman, M. Ali, Y. N. Mabkhot, and H-K. Fun. Synthesis, spectroscopic investigations (X-Ray, NMR and TD-DFT), antimicrobial activity and Molecular docking of 2,6-Bis(hydroxy(phenyl)methyl)cyclohexanone. Molecules 2015, 20, 13240-13263.
  56. Y. N. Mabkhot, S. S. Al-Showiman, A. Barakat, S.  Yousuf, M. I. Choudhary.  Regioselective synthesis and crystal structure of ethyl-4-acetyl-5-((2- ethoxy-2-oxoethyl)thio)-3-hydroxythiophene-2-carboxylate, C13H16O6S2. Z. Kristallogr. NCS 2015, 230, 241-242.
  57. Y. N. Mabkhot, S. S. Al-Showiman, A. Barakat, S.  Yousuf, M. I. Choudhary. Crystal structure of 1-acetylimidazolidine-2,4-dione monohydrate, C5H8N2O4. Zeitschrift für Kristallographie –NCS. 2015, 230, 255-256.
  58. A.Barakat, A. M. Al-Majid, Y. N. Mabkhot, H. A. Ghabbour, H-K. Fun. X-Ray Crystal Structure of (Z)-5-(3-methylbenzylidene)-2-thioxothiazolidin-4-one. Z. Kristallogr. NCS 2015, 230, 257-258.
  59. A.Barakat, M. S. Islam, A. M. Al-Majid, H. A. Ghabbour, H-K. Fun, K. Javed, R. Imad, S. Yousuf, M. I. Choudhary, A. Wadood. Synthesis, In vitro Biological Activities and In Silico Study on Dihydropyrimidines Derivatives. Bioorganic & Medicinal Chemistry, 2015, 23, 6740-6748.
  60. A.Barakat, M. S. Islam, A. M. Al-Majid, Z. Al-Othman, S.M. Soliman, H. A. Ghabbour, H-K Fun. Synthesis of novel 5-monoalkylbarbiturates derivatives-New access to 1,2-oxazepines. Tetrahedron letters, 2015, 56, 6984–6987.
  61. A. Barakat, Abdullah M.Al-Majid,  S.M. Soliman, G. Lotfy, H. A. Ghabbour, H-K. Fun, A. Wadood. New diethyl ammonium salt of thiobarbituric acid derivative: Synthesis, molecular structure investigations and docking studies. Molecules, 2015, 20, 20642–20658.
  62. A.Barakat, A. M. Al-Majid, G.Lotfy, F. Arshad, S. Yousuf, M. Iqbal Choudhary, Sajda Ashraf and Zaheer Ul-Haq. Synthesis and Dynamics Studies of Barbituric Acid Derivatives as Urease Inhibitors. Chemistry Central Journal, 2015, 9 (1), 63.
  63. M.S. Islam, A. Barakat, A. M. Al-Majid, S. M. Soliman, H. A. Ghabbour, H-K. Fun. Crystal Structures of 7,11-bis(2,4-dichlorophenyl)-2,4-dimethyl-2,4-diazaspiro[5.5]undecane -1,3,5,9-tetraone  and its computational studies. Journal of Chemical Sciences, 2015, 127(11), 2039-2050.
  64. Y. N. Mabkhot, Salah S. Aladdi, S. S. Al-Showiman, Abdullah M. A. Al-Majid, A. Barakat, Hazem A. Ghabbour and Mohamed R. Shaaban.  Synthesis, and characterization of novel thieno-fused bicyclic compounds through novel enaminone containing thieno[2,3-b]pyridine scaffold. Journal of Chemistry, 2015, (2015), Article ID 382381, 8 pages.
  65. A. M. Al Majid, A.Barakat, M. H.M. Al-Agamy, Y.N. Mabkhot.  Synthesis, and Characterization of a new series of sulfite and sulfate derivatives of d-Mannitol. Journal of Saudi Chemical Society 2016, 20, pp. 307-312.
  66. A.Barakat, A. M. Al-Majid, M. Shahidul Islam, I. Warad, V. H Masand, S. Yousuf and M. Iqbal Choudhary. Molecular structure investigation and biological evaluation of Michael adducts derived from dimedone. Research on Chemical Intermediates.  2016, 42(5), 4041-4053.
  67. E. H. El Ashry, Y. El Kilany, N. M. Nahas, A. Barakat, N. Al-Qurashi,H. A. Ghabbour, and H. K. Fun. Synthesis and Crystal Structures of Benzimidazole-2-thione Derivatives by Alkylation Reactions. Molecules, 2016, 21(1), 12.          
  68. Y. N. Mabkhot, F. D. Aldawsari, S. S. Al-Showiman, A. Barakat, S. M. Soliman, M.I. Choudhary, S. Yousuf, T.B. Hadda, M. S. Mubarak. Synthesis, Molecular Structure Optimization, and Cytotoxicity Assay of a Novel 2-Acetyl-3-amino-5-[(2-oxopropyl)sulfanyl]-4-cyanothiophene. Molecules, 2016, = 21(2), 214; doi:10.3390/molecules21020214.
  69. A.Barakat, H. A. Ghabbour, A. M. Al-Majid, C. K.Quah, H-K. Fun. Crystal structure of 5,5'-((4-(trifluoromethyl)phenyl)methylene)bis(1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione)-NHEt2-DCM (1:1:1). Zeitschrift für Kristallographie –NCS. 2016, 231, 321-323.
  70. A.Barakat, H. A. Ghabbour, A. M. Al-Majid, M. M. Said, E-S. El Tamany, H-K. Fun. Crystal structure of (Z)-5-(4-chlorobenzylidene)-2-thioxothiazolidin-4-one compound -dimethylsulfoxide(1:1). Zeitschrift für Kristallographie –NCS. 2016, 231, 319-320.
  71. Y. N. Mabkhot, A. Barakat, H. A. Ghabbour, H-K. Fun. Crystal structure of 2-amino-N-(4-methoxyphenyl)benzamide, Zeitschrift für Kristallographie –NCS.2016, 231, 203-204.
  72. A.Barakat, S. Naveen, N. Renuka, K. Ajay Kumar, M. Abdoh, I. Warad, N. K. Lokanath, Crystal stucture of 3-(Thiophen-2-yl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazole-1-carboxamide. Zeitschrift für Kristallographie –NCS. 2016, 231, 267-269.
  73. Ahmed T. A. Boraei, E-H. E-Ashry, A. Barakat, Hazem A. Ghabbour. Synthesis of new functionalized indoles based on Ethyl indol-2-carboxylate. Molecules, 2016, 21, 333; doi:10.3390/molecules21030333.
  74. M. S. Islam, A. M. Al-Majid, A. Barakat, H. A. Ghabbour, A. F. M. Motiur Rahman, K. Javaid, R. Imad, S. Yousuf, M. I. Choudhary. A concise synthesis and evaluation of new malonamide derivatives as potential α-glucosidase inhibitors. Bioorganic & Medicinal Chemistry, 2016, 24, 1675-1682.
  75. A.Barakat, H. A. Ghabbour, A. M. Al-Majid, E-S.H. El Ashry, I. Warad, H-K. Fun. Crystal structure of diethylammonium 5-((4-fluorophenyl)(6-hydroxy-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-olate. Z. Kristallogr. NCS 2016, 231(2):507–509.
  76. Y.N. Mabkhot, A.Barakat, S. S. Al-Showiman, W. Frey, A. H. Hamdi, H. A. Ghabbour. Crystal structure of1-(5-benzoyl-4-methyl-2-(phenylamino)thiophen-3-yl)ethan-1-one, a structure with Z′ = 6, C20H17NO2S,. Z. Kristallogr. NCS 2016, 231(2):517–520.
  77. Y.N. Mabkhot, A. Barakat, S. S. Al-Showiman, W. Frey, S. Uzzaman, H. A. Ghabbour. Crystal structure of diethyl 3-methyl-4-phenylthieno[2,3-b]thiophene-2,5-dicarboxylate. Z. Kristallogr. NCS 2016, 231(2):521–523.
  78. Y. N. Mabkhot, A. Barakat, S. S. Al-Showiman, S.M. Soliman, W. Frey, H. A. Ghabbour. Crystal structure of (E)-2-(bis(methylthio)methylene)-1-phenyl-3-(2-phenylhydrazono)butan-1-one.  Z. Kristallogr. NCS 2016, 231(2):475–476.
  79. Y. N. Mabkhot, A. Barakat, S. S. Al-Showiman, S.M. Soliman, W. Frey, H. A. Ghabbour. Crystal structure of 2-(bis(methylthio)methylene)-1-phenylbutane-1,3-dione. Z. Kristallogr. NCS 2016, 231(2): 473–474.
  80. S. Radi, M. El-Massaoudi, Y.N. Mabkhot, A. Barakat, H.A. Ghabbour. Crystal structure of 1,1'-(propane-1,3-diyl)bis(5-methyl-1H-pyrazole-3-carbaldehyde), C14H18N4O2, Z. Kristallogr. NCS 2016, 231(2): 577–578.
  81. A.Barakat, M. Ali,  A. M. Al-Majid, M. S. Islam, H. A. Ghabbour, Crystal structure of 5-((4-bromophenyl)(2-hydroxy-6-oxocyclohex-1-en-1-yl)methyl)-6-hydroxy-1,3-dimethylpyrimidine-2,4(1H,3H)-dione, C19H19BrN2O5. Z. Kristallogr. NCS 2016; 231(3): 843–845.
  82. A.Barakat, A. M. Al-Majid, H. A. Ghabbour, Qurat-ul-ain, R.Imad, K. Javeed, N. N.Shaikh, S. Yousuf, M. Iqbal Choudhary, A. Wadood. Synthesis, X-Ray Crystal Structures, Biological Evaluation and Molecular docking studies of a Series of Barbiturate Derivatives. Journal of Chemistry, 2016, vol. 2016, Article ID 8517243, 11 pages, 2016. doi:10.1155/2016/8517243.
  83. A.Barakat, A. M. Al-Majid, M. Ali, H. A. Ghabbour, M.S.Al-Marashdah, M. Rafiq Siddiqui. Crystal structure of 6-hydroxy-5-((2-hydroxy-6-oxocyclohex-1-en-1-yl)(phenyl)methyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione, C19H20N2O5. Z. Kristallogr. NCS 2016; 231(3): 849–851.
  84. Z. Ul-Haq, S. Ashraf, A. M. Al-Majid, A. Barakat. 3D-QSAR Studies on Barbituric Acid Derivatives as Urease Inhibitors and the Effect of Charges on the Quality of a Model. Int. J. Mol. Sci. 2016, 17, 657.
  85. I. Warad, F. Al-Rimawi, A. Barakat, S. Affouneh, N. Shivalingegowda, N. K. Lokanath, I.M. Abu-Reidah. Synthesis, spectral, thermal, crystal structure, Hirschfeld analysis of [bis(triamine)Cadimium(II)][Cadimum(IV)tetra-bromide] complexes and their thermolysis to CdO nanoparticles. Chemistry Central Journal, 2016, 10: 38, DOI 10.1186/s13065-016-0183-y.
  86. Y. N. Mabkhot, N. A. Kheder, A. Barakat, M. I. Choudhary, S. Yousuf and W.Frey. Synthesis, Antimicrobial, Anti-Cancer and Molecular Docking of Two Novel Hitherto Unreported Thiophenes. RSC adv., 2016, 6, 63724–63729.
  87. A.Barakat, M. S. Islam, A. M. Al-Majid, H. A. Ghabbour, S. Yousuf, M. Ashraf, Nimra N. Shaikh, M. I. Choudhary, R. Khalil, Z. Ul-Haq. Synthesis of pyrimidine-2,4,6-trione derivatives: anti-oxidant, Anti-cancer, α-glucosidase, ß-glucuronidase inhibiton and their molecular docking studies. Bioorganic Chemistry, 2016, 86, 72-79.
  88. A.Barakat, S. M.  Soliman, H. A. Ghabbour, M. Ali, A.M. 
    Al-majid, M. S.Islam, A. Ghafar. Molecular structure, spectroscopic and DFT computational studies of arylidene -1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione. Crystals, 2016, 6(9), 110.
  89. A.Barakat, H. A. Ghabbour, A. M. Al-Majid, M.S. Islam, M. R. Shaik. Crystal structure of diethylammonium 1,3-dimethyl-2,4,6-trioxohexahydropyrimidin-5-ide, C10H19N3O3. Zeitschrift für Kristallographie –NCS. 2016, 231(4), 1063–1064.
  90. A.Barakat, H. A. Ghabbour, B. M. Al-Qahtani, M. Ali, A. M. Al-Majid. Crystal structure of 5-(3-fluorobenzylidene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione. Zeitschrift für Kristallographie –NCS. 2016, 231(4): 1059–1061.
  91. A.Barakat, H. A. Ghabbour, S. Atef, A. M. Al-Majid,  M. S. Islam, M. Ali, 5-[(3-Fluorophenyl)(2-hydroxy-6-oxocyclohex-1-en-1- yl)methyl]-6-hydroxy-1,3-dimethylpyrimidine-2,4(1H, 3H)-dione. Molbank, 2016, 2016, M910.
  92. Y. A. M. M. Elshaier, A. Barakat, B. M. Al-Qahtany, A. M. Al-Majid, M. H. Al-Agamy. Synthesis of Pyrazole-Thiobarbituric Acid Derivatives: Antimicrobial Activity and Docking Studies. Molecules, 2016, 21, 1337.
  93. Y.N. Mabkhot, A. Barakat, T. T. El-Idreesy, S. M. Soliman, H.A Ghabbour, S.S. Al-Showiman. Synthesis, Characterization and Computational Studies of A Novel thieno[2,3-b]thiophene Derivative. Journal of Molecular structure, 2016, 1130, 62-70.
  94. A.Barakat, B.M. Al-Qahtani, A. M. Al-Majid, M. Ali, Y.N. Mabkhot, M. H.M. Al-Agamy, A.Wadood. Synthesis, Characterization, anti-microbial Activity and Molecular Docking Studies of combined Pyrazol-Barbituric acid pharmacophore. Tropical Journal of Pharmaceutical Research, 2016, 15 (10): 1319-1326.
  95. S. M. Soliman, A. Barakat. Decomposition of intermolecular interactions in the crystal structure of some diacetyl platinum(II) complexes; Combined Hirshfeld, AIM and NBO analyses. Molecules, 2016, 21(12), 1669.
  96. F. A. Saleemh, S. Musameh, A. Sawafta, P. Brandao, C. J. Tavares, S.Ferdov, A. Barakat, A. Al Ali, M. Al-Noaimi, I. Warad. Diethylenetriamine/diamines/copper (II) complexes [Cu(dien)(NN)]Br2: Synthesis, solvatochromism, thermal, electrochemistry, single crystal, Hirshfeld surface analysis and antibacterial activity. Arabian journal of chemistry, 2017, 10, 845–854.
  97. M.S. Islam, A. Barakat, A. M. Al-Majid, H. A. Ghabbour, H-K. Fun, M. R. Siddiqui. Stereoselective Synthesis of Spiro[5.5]undecane Derivatives via Base Promoted [5+1] Double Michael Addition of N,N-Dimethylbarbituric Acid to Dienones. Arabian Journal of Chemistry, 2017, 10, 1-9.
  98. A.M. Al-Majid, M. S. Islam, A. Barakat, Nasser Elkahatany, S.S Yousuf, Iqbal Choudhary. Tandem Knoevenagel-Michael reactions in aqueous diethylamine medium: A greener and efficient approach to bis-Dimedone derivatives. Arabian Journal of Chemistry, 2017, 10, 185 – 193.
  99. S. uzzaman, H.Khanam, A. Mashrai, M. Asif, A. Ali, A. Barakat, Y. N. Mabkhot. Synthesis, crystal structure, Hirshfeld surfaces, thermal, mechanical and dielectrical properties of cholest-5-ene. Journal of Taibah University for Science 2017, 11 141–150.
  100. I. Warad, A. Barakat. Synthesis, physicochemical analysis of two new hemilabile ether-phosphine ligands and their first stable cis-bis-ether-phosphine/Cobalt(II) tetrahedral complexes. Journal of Molecular Structure, 2017, 1134, 17-24.
  101. A.Barakat, S. M. Soliman,Y. A. M. M.  Elshaier,M. Ali, A. M. Al-Majid, H. A. Ghabbour. Molecular structure and spectroscopic investigations combined with hypoglycemic/anticancer and docking studies of a new barbituric acid derivative. Journal of Molecular Structure.  2017, 1134, 99–111.
  102. A.Barakat, M. Islam, A. Al-Majid, S. M. Soliman, H. Ghabbour, S. Yousuf, M. Iqbal, Choudhary, Z. Ul-Haq. Synthesis, molecular structure, spectral analysis and biological activity of new malonamide derivatives as α-glucosidase inhibitor. Journal of Molecular structure 2017, 1134, 253-264.
  103. A.Barakat, M. Ali, A. M. Al-Majid, H. A. Ghabbour. Crystal structure of 2-(4-oxo-2-thioxothiazolidin-3-yl) acetic acid monohydrate, C5H7NO4S2. Zeitschrift für Kristallographie –NCS. 2017, 232(1): 141–142.
  104. A.Barakat and A. M. Al-Majid, Synthesis, structural characterization of monodentate phosphite ligands and phosphite ruthenium complexes derived from D-mannitol. Arabian journal of chemistry, 2017, 10, S894-S900.
  105. G. Lotfy, El Sayed H. El Ashry, M. M. Said, El Sayed El Tamany, A. Al-Dhfyan, Y.M.  Abdel Aziz, A. Barakat. Synthesis of new spirooxindole-pyrrolothiazoles derivatives: Anti-cancer activity and molecular docking. Bioorganic & Medicinal Chemistry, 2017, 25, 1514–1523.
  106. S. M. Soliman, Y. N. Mabkhot; A. Barakat, H. Ghabbour. A Highly distorted hexacoordinated silver(I) complex; synthesis, crystal structure and DFT studies. Journal of Coordination Chemistry. 2017, 70, 1339-1356.
  107. Y.N. Mabkhot, F. A. Al-aizari, S. Al-Showiman, A. Barakat, H. A. Ghabbour, W. Frey. Crystal structure of 1,1,(3,4-dihydroxythieno[2,3-b] thiophene-2,5-diyl)bis(2-bromoethanone(, C10H6Br2O4S2 Zeitschrift für Kristallographie –NCS. 2017, 232(2): 255–256.
  108. A. Barakat, Saied M. Soliman, Hazem A. Ghabbour, M. Ali, A. M.Al-Majid, I. Warad. Intermolecular interactions in crystal structure, Hirshfeld surface, characterization, DFT and thermal analysis of 5-((5-bromo-1H-indol-3-yl)methylene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione indole.  Journal of Molecular Structure.  2017, 1137, 354-361.
  109. A.Barakat, A. M. Al-Majid, S. M. Soliman, M.S. Isalm, H. M. Ghawas,S. Yousuf, M. I. Choudhary, A. Wadood. Monoalkylated barbiturate derivatives: X-ray crystal structure, theoretical studies, and biological activities. Journal of Molecular Structure, 2017, 1141, 624–633.
  110. A.Barakat, A. M. Al-Majid, S. M. Soliman, M.S. Isalm, H. M. Ghawas,S. Yousuf, M. I. Choudhary, A. Wadood. Corrigendum to “Monoalkylated barbiturate derivatives: X-ray crystal structure, theoretical studies, and biological activities” [J. Mol. Struct. 1141 (2017) 624–633]. Journal of Molecular Structure, 2017, 1144, 24.
  111. G. lotfy, M. M. Said, El Sayed H. El Ashry, El Sayed H. El Tamany, Y. M.  Abdel Aziz, S. M. Soliman, A. Barakat. Synthesis, structure combined with conformational analysis, biological activities and docking studies of bis benzylidene cyclohexanone derivatives. Journal of Saudi Chemical Society, 2017, 21, 619-632.
  112. E-S. H. El Ashry, L. Awad, S.M.Soliman, H.A. Ghabbour, A.Barakat, M. N. Abd Al Moaty. Tautomerism aspect of thione-thiol combined with spectral investigation of some 4-amino-5-methyl-1,2,4-triazole-3-thione Schiff's bases. Journal of Molecular Structure 2017, 1146, 432-440.
  113. I. Warad, S. Musameh, I. Badran, N.N. Nassar, P. Brandao, C.J. Tavares, A.Barakat,   Synthesis, solvatochromism and crystal structure of trans-[Cu(Et2NCH2CH2NH2)2.H2O](NO3)2 complex: Experimental with DFT combination. Journal of Molecular Structure 2017,  1148, 328-338.
  114. A. Barakat, M. Ali, A. M. Al-Majid, S. Yousuf, M. I. Choudhary, R.Khalil, Z. Ul-Haq. Synthesis of thiobarbituric acid derivatives: In vitro α-glucosidase inhibition and molecular docking studies. Bioorganic Chemistry 2017, 75, 99-105.
  115. S. Boussaidi, A. Amkassou, H. Zgou, A. Eddiouan, Y.N. Mabkhot, A. Barakat, H. Chaib., T. Ben Hadda, Theoretical study of organic materials based on Thieno [2, 3-b] thiophene as layer of bulk heterojunction solar cells. Moroccan Journal of Chemistry, 2017, 5(3), 425-437.‏
  116. A. Barakat, S. M. Soliman, A. Al-majid, M. Ali, M.S. Islam,
    Y. A. M. M. Elshaier, H. A. Ghabbour. New spiro-oxindole constructed with pyrrolidine/thioxothiazolidin-4-one derivatives: Regioselective synthesis, X-ray crystal structures, Hirshfeld surface analysis, DFT, docking and antimicrobial studies. Journal of Molecular Structure. 2018, 1152, 101-114.
  117. E-S. H. El Ashry, L. F. Awad, M. N. A-A. Moaty, H. A. Ghabbour, A. Barakat. Stereoselective synthesis of novel thioglycosyl heterocycles. Journal of Molecular Structure. 2018, 1152, 87-95.
  118. A.Barakat, M. Ali, A. M. Al-Majid, S. M. Soliman, H. A. Ghabbour. Analytical studies of  6-hydroxy-5-((2-hydroxy-6-oxocyclohex-1-en-1-yl)(2-nitrophenyl)methyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione. Russian Journal of General Chemistry, 2018, 88(11) 2381–2387.
  119. A.Barakat, M. S. Islam, S. Atef, A. M. Al-Majid, H. A. Ghabbour, A. Zarrouk, I. Warad. Quantum chemical insight into the molecular structure of L-chemosensor 1,3-dimethyl-5-(thien-2-ylmethylene)-pyrimidine-2,4,6-(1H,3H,5H)-trione: Naked-eye colorimetric detection of copper(II) anions. Journal of Theoretical and Computational Chemistry, 2018, 17(1) 1850005 (23 pages).
  120. G. Lotfy, El Sayed H. El Ashry, M. M. Said, El Sayed El Tamany, A. Al-Dhfyan, Y.M.  Abdel Aziz, A.M. Al-Majid, A. Barakat. Regio- and stereoselective synthesis of novel spiro-oxindole via 1,3-dipolar cycloaddition reaction. Anti-cancer and molecular docking studies. Journal of Photochemistry and Photobiology B: Biology, 2018, 180, 98-108.
  121. A. Barakat, A. Al-majid, B. M. Al-Qahtani, M. Ali, 
    Mohamed Teleb, M. H.M. Al-Agamy, S. Naz, Z.
    -ul-haq. Synthesis, antimicrobial activity, pharmacophore modeling and molecular docking studies of new pyrazole‑dimedone hybrid architectures. Chemistry Central Journal, 2018, 12:29.
  122. A. Barakat, M. Ali, S. M. Soliman, A-M. Abu-Elfotouh, A. M. Al-Majid, H. A. Ghabbour. New hybrid of barbituric acid motif: Synthesis, X-ray single crystal, DFT and Hirshfeld surface analyses. Research on Chemical Intermediates. 2018, 44(7), 4213-4225.
  123. S. M. Soliman, A. Barakat, M. S. Islam, H. A. Ghabbour. Synthesis of rare Ag(I)-malonamide complex: Single-crystal X-ray crystallography and DFT Studies. Molecules, 2018, 23, 888.
  124. A. Barakat, M.S. Islam, H. M. Ghawas, A. Al-majid, F. F. El-Senduny F.A. Badria, Y. A. M. M. Elshaier, H. A. Ghabbour. Substituted spirooxindole derivatives as potent anticancer agents through inhibition of phosphodiesterase 1. RSC Advances, 2018, 8, 14335.
  125. M. S. Islam,A. Barakat, A. M.Al-Majid, M. Ali, S. Yousuf, M. I. Choudhary, R. Khalil, Z. Ul-Haq. Catalytic Asymmetric Synthesis of Indole Derivatives as Novel α-Glucosidase Inhibitors in Vitro. Bioorganic Chemistry 2018, 79, 350-354.
  126. Caroline M. Zinser, Katie G. Warren, Rebecca E. Meadows, Fady Nahra, A. M.Al-Majid, A. Barakat, M. S. Islam, Steven P. Nolan, Catherine S. J. Cazin. Towards Environmentally Friendlier Suzuki-Miyaura Reactions with Precursors of Pd-NHC (NHC = N-Heterocyclic Carbene) Complexes. Green Chemistry, 2018, 20, 3246-3252. *
  127. S. M. Soliman, Jörg Albering, A.Barakat. Unexpected Formation of Polymeric Silver(I) complexes of azine-type ligand via self assembly of Ag-salts with isatin oxamohydrazide; Synthesis, crystal structure and DFT studies. Royal Society Open Science. 2018, 5: 180434.
  128. Mezna S. Altowyan, M. Ali, Obaid S AlRuqi, A. M. Al-Majid, A.Barakat, Crystal structure of 5,5'-((3-hydroxy-4-methoxyphenyl)methylene)bis(1,3-diethyl-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one. Zeitschrift für Kristallographie - New Crystal Structures (ZKRIST-NCS). 2018, 233(5): 919–921.
  129. Mezna S. Altowyan, M. Ali, S. M. Soliman, Naser Almoqbl, A. M. Al-Majid, A. Barakat, Crystal structure of 6-hydroxy-5-((2-hydroxy-6-oxocyclohex-1-en-1-yl)(4-methoxyphenyl)methyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione. Zeitschrift für Kristallographie - New Crystal Structures (ZKRIST-NCS). 2018, 233(4): 747–749.
  130. M.S. Islam, A. Barakat, A. M. Al-Majid, S. M. Soliman, M. R. Shaik, M. Ali, H. A. Ghabbour. Chemical reactivity, molecular structure, spectroscopic and DFT computational studies of new spiroheterocycle. Materials Express, 2018, 8(4)335-344.
  131. Taghrid S. El Mahdy, Mohamed H. Al-Agamy, M. Emara, A. Barakat, Richard V. Goering. Complex Clonal Diversity of Staphylococcus aureus Nasal Colonization among Community Personnel, Healthcare Workers, and Clinical Students in the Eastern Province, Saudi Arabia. BioMed Research International. 2018, vol. 2018, Article ID 4208762, 9 pages.
  132. Mezna S. Altowyan, A. Barakat, S. M. Soliman, A. M. Al-Majid, M. Ali, Y. A. M. M. Elshaier, H. A. Ghabbour, A New Barbituric Acid Derivatives as Reactive Oxygen Scavenger: Experimental and Theoretical Investigations. Journal of Molecular Structure 2019, 1175, 524-535.
  133. I. Warad, M. Al-Nuri, O. Ali, I. M. Abu-Reidah, A. Barakat, T. B. Hadda, A. Zarrouk, S.Radi, R. Touzani and H. Elmsellem. Synthesis, physico-chemical, Hirschfield surface and DFT/B3LYP calculation of two new hexahydropyrimidine heterocyclic compounds. Iranian Journal of Chemistry and Chemical Engineering (IJCCE), 2019, 38, No. 4, 59-68.
  134. M.S. Islam, H. M. Ghawas, F. F. El-Senduny, A. Al-majid, F.A. Badria, Y. A. M. M. Elshaier, A. Barakat, Synthesis of new thiazolo-pyrrolidine /Spirooxindole tethered to 3-acylindole as anticancer agents. Bioorganic Chemistry, 2019, 82, 423-430.
  135. Mezna S. Altowyan, A.Barakat, A. M. Al-Majid, H. A. Ghabbour, A. Zarrouk, I. Warad. Vibrational spectral analysis, XRD-properties, computation, exo/endo isomerization and non-linear optical crystal of 5-((5-chloro-1H-indol-2-yl)methylene)-1,3-diethyl-2-thioxodihydropyrimidine-4,6 (1H,5H)-dione. BMC Chemistry 2019, 13:11.
  136. Y. N. Mabkhot, S. S. Al‑Showiman, A. Barakat, S. M. Soliman, N. A. Kheder, M. M. Alharbi, A. Asayari, A. Bin Muhsinah, A. U. and S. L.Badshah. Computational studies of 2-(4-oxo-3-phenylthiazolidin-2-ylidene) malononitrile. BMC Chemistry 2019, 13:25.
  137. A. Barakat, M.S. Islam, H. M. Ghawas, A. Al-majid, F. F. El-Senduny F.A. Badria, Y. A. M. M. Elshaier, H. A. Ghabbour. Design and Synthesis of New Substituted Spirooxindoles as Potential Inhibitors of the MDM2−p53 Interaction. Bioorganic Chemistry, 2019, 86, 598-608. *
  138. M. S. Altowyan, S. Atef, M. H. Al-Agamy, S.M. Soliman, M. Ali, M.R. Shaik, M. I. Choudhary, H. A. Ghabbour, A. Barakat, Synthesis and characterization of a spiroindolone pyrothiazole analog via X-ray, biological, and computational studies. Journal of Molecular Structure 2019, 1186, 384-392.
  139. S.M. Soliman, and A.  Barakat, Self-assembly of azine-based hydrolysis of pyridine and isatin oxamohydrazides with AgNO3; synthesis and structural studies of a novel four coordinated Ag(I)-azine 2D coordination polymer. Inorganica Chemica Acta 2019, 490, 227-234.
  140. A. M. Al-Majid; M. S. Islam, S. Atef, F. F. El-Senduny, F. A. Badria, Y. A. M. M. Elshaier; M. Ali, A. Barakat, A. F. M. Motiur Rahman, Synthesis of pyridine-dicarboxamide-cyclohexanone derivatives:  Anti-cancer and α-glucosidase inhibitory activities and in silico study. Molecules, 2019, 24(7), 1332.
  141. A. Barakat, F. F. El-Senduny,Z. Almarhoon,F.A. Badria,A. M. Al-Majid, H. A. Ghabbour, A. El-Faham. Synthesis, X-ray crystal structures, and anti-proliferative activities of new s-triazine-hydroxybenzylidene hydrazone derivatives. Journal of Chemistry 2019, Volume 2019, Article ID 9403908, 10 pages.
  142. Fady Nahra, A. M.Al-Majid, A. Barakat, M. S. Islam, Steven P. Nolan, Catherine S. J. Cazin. Palladate pre-catalysts for the formation of C-N and C-C bonds. Organometallics, 2019, 38, 14, 2812-2817.*
  143. M. S. Altowyan, A. Barakat, A. M. Al-Majid, H.A. Al-Ghulikah, Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase. Molecules, 2019, 24(12). pii: E2342. doi: 10.3390/molecules24122342.
  144. G. Lotfy,M. M. Said, E-S.H. El Ashry, E-S. H. El Tamany, Y. M. Abdel Aziz, S. M. Soliman, A. M. Al-Majid, H.A Ghabbour, A. Barakat,Synthesis and X-ray Crystal structure combined with conformational and Hirshfeld analyses of chaclones based on cyclohexanone scaffold. Journal of Molecular Structure, 2019, 1198, 126873.
  145. G. Lotfy,Y. M. Abdel Aziz, M. M. Said, E-S.H. El Ashry, E-S. H. El Tamany, A. Barakat, H. A. Ghabbour, S. Yousuf, Z. Ul-Haq and M. I. Choudhary.Synthesis of oxindole analogues, biological activity and in silico investigation. ChemistrySelect 2019, 4(35), 10510-10516.
  146. F. Badria, S. Atef, A. Al-Majid, M.S. Islam, M. Ali, Y. Elshaier, H. Ghabbour, A. Barakat, Synthesis and inhibitory effect of some indole-pyrimidine-based hybrid heterocycles on α-glucosidase and α-amylase as potential hypoglycemic agents. ChemistryOpen 2019, 8, 1288–1297.
  147. F. A. Badria, S. M. Soliman, M. S. Islam, A. M. Al-Majid, N. Dege, H. A. Ghabbour, M. Ali, F. F. El-Senduny and A. Barakat. Anti-cancer indole-based chalcones: A structural and theoretical analysis. Molecules. 2019, 24, 3728.
  148. M. S.Islam, F. Nahra, N.Tzouras, A. Barakat, S.P. Nolan,  A. Al Majid, Mizoroki-Heck cross-coupling of acrylate derivatives with aryl halides catalyzed by palladate pre-catalysts. European Journal of Inorganic Chemistry, 2019, 4695–4699.
  149. A. T. A. Boraei, H. A. Ghabbour, M. S. Gomaa,El Sayed H. El Ashry, and. A. Barakat. Synthesis and anti-proliferative assessment of triazolo-thiadiazepine and triazolo-thiadiazine scaffolds. Molecules. 2019, 24(24), 4471.
  150. M. S. Altowyan, M. Ali,S.M. Soliman, A. M. Al-Majid, M. S. Islam, S. Yousuf, M. I. Choudhary, H. A. Ghabbour, and A. Barakat. Synthesis, computational studies and biological activity of oxamohydrazide derivatives bearing isatin and ferrocene scaffolds. Journal of Molecular Structure, 2020, 1202,127372.
  151. A.M. Al-Majid, H. M. Ghawas,M. S. Islam, S. M. Soliman, F. F. El-Senduny, F. A. Badria, M. Ali, M. R. Shaik, H.A. Ghabbour, and A. Barakat, Synthesis of spiroindolone analogue via three components reaction of olefin with isatin and sarcosine: Anti-proliferative activity and computational studies. Journal of Molecular Structure, 2020, 1204, 127500.
  152. A.Barakat, S. M. Soliman, A.El-Faham, M. Ali, A.M. Al-Majid, S. Yousuf and M. Iqbal Choudhary. Three Multi Components Reaction: Synthesis and X-ray single crystal of hydroacridinone based hydrazino-s-triazine derivative as a new class of urease inhibitor. Crystals, 2020, 9, 14.
  153. A. Barakat,S. M. Soliman,M. Ali, A. Elmarghany, A. M.Al-Majid, S. Yousuf, Z.Ul-Haq,  M. Iqbal Choudhary,  and A. El-Faham. Synthesis, crystal structure, evaluation of urease inhibition potential and the docking studies of cobalt(III) complex based on barbituric acid Schiff base ligand. Inorganica Chimica Acta. 2020, 503, 119405.
  154. A. Barakat, S. M. Soliman, S.Alshahrani, M. S. Islam, M. Ali, A. M. Al-Majid and S. Yousuf. Synthesis, X-ray Single Crystal, Conformational Analysis and Cholinesterase Inhibitory Activity of a New Spiropyrrolidine Scaffold Tethered Benzo[b]Thiophene Analogue. Crystals 2020, 10(2), 120.
  155. A. T. A. Boraei, A A. Sarhan, S. Yousuf, A.
    Barakat    . Synthesis of new multi-nitrogen/sulfur heterocyclic systems via
    linking four rings: Indole, 1,2,4-triazole, pyridazine and quinoxaline. Molecules, 2020, 25(3), pii: E450.
  156. M. Ali, A. Barakat, A. El-Faham, H. H. Al-Rasheed, K. Dahlous, A. M. Al-Majid, A. Sharma, S. Yousuf, M. Sanam, Z. Ul-Haq, M. Iqbal Choudhary, B. G. de la Torre, F, Albericio. Synthesis and characterization of thiobarbituric acid enamine derivatives, and evaluation of their α-glucosidase inhibitory and anti-glycation activity. Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35:1, 692-701.
  157. Mezna S. Altowyan, A. Barakat, A. M. Al-Majid, H.A. Al-Ghulikah, New Spiroindolone Bearing Benzofuran Moiety as High Effective and Selective for COX-1 Inhibitor with TNF-α, and IL-6 inhibitory activity. Saudi Journal of biological Science, 2020, 27, 1208-1216.
  158. A. T. A. Boraei, H. A. Ghabbour, A. Sarhan, A. Barakat. Expeditious green synthesis of novel 4-methyl-1,2,5,6-tetraazafluoranthen-3(2H)-one analogue from ninhydrin: N/S-alkylation and aza-Michael addition. ACS Omega, 2020, 5, 10, 5436-5442.
  159. M. Islam, A. Al Majid, F. F. El-Senduny, F. A. Badria, A. Barakat, Y. A. M. M. Elshaier, Synthesis and Antiproliferative Acitiviy of new Spiro[Pyrrolidine-thiazolo-Oxindoles] Tethered 3,5-Dibromoisatin as Anticancer Agents. Applied Sciences, 2020, 10(6), 2170.
  160. A. Barakat, S. M. Soliman, M. Haukka, A. M.Al-Majid, M. S. Islam, M. Ali, and M. R. Shaik. One-Pot Synthesis, X-Ray Single Crystal and Molecular Insight of Enaminone-Based β-Morpholino-/ N-Methylpiperazinyl-/ Pyrrolidinyl Propio-phenone. Crystals, 2020, 10(4), 282.
  161. A.A. M. Sarhan, A. T. A. Boraei, A.Barakat, M. S. Nafie. Discovery of hydrazide based pyridazino[4,5-b]indole scaffold as a new phosphoinositide 3-kinase (PI3K) inhibitors for breast cancer. RSC Advances, 2020, 10, 19534 - 19541.
  162. M. Ali, A. Barakat, A. El-Faham, A. M. Al-Majid, S. Yousuf, R. Khalil, Z. Ul-Haq and M. Iqbal Choudhary, Beatriz G. de la Torre, Fernando Albericio. Enamine barbiturates and thiobarbiturates as a new class of bacterial urease inhibitors. Applied Sciences, 2020, 10(10), 3523.
  163. S. M. Soliman, J. Lasri, M. Haukka, A.  Elmarghany,A. M. Al-Majid, A.El-Faham, andA. Barakat.Synthesis, X-ray structure, Hirshfield analysis and DFT studies of a new Pd(II) complex with anionic s-triazine based NNO-donor ligand. Journal of Molecular Structure. 2020, 1217,128463.
  164. E. M. Gad, M.S. Nafie, E-S. H. El Tamany, M. S. A. Gabr, A. Barakat, A. T. A. Boraei. Discovery of New Apoptosis-Inducing Agents for Breast Cancer Based on Ethyl 2-amino-4,5,6,7-tetra hydrobenzo[b]thiophene-3-carboxylate: Synthesis, in vitro, in vivo, and in Silico Evaluation. Molecules 2020, 25(11), 2523.
  165. A. Sharma, A. Barakat, H. H. Al-Rasheed, A. M. Al-Majid, S. Yousuf, M. Iqbal Choudhary, A. El-Faham,B.G. de la Torre,and F. Albericio. Crystal Structure and Theoretical Investigation of Thiobarbituric Acid Derivatives as Non-Linear Optical (NLO) materials. Crystals 2020, 10(6), 442.
  166. A. T. A. Boraei, S. M. Soliman, S. Yousuf, M. Bibi,A. Barakat. N-Acetyl Indole Linked to Fused Triazolo/Thiadiazole Scaffold: Synthesis, Single Crystal X-Ray Structure and Molecular Insight. Crystals 2020, 10(7), 600.
  167. A. Badr, A. Barakat, J. Albering, M. Sharaf, Z. Ul-Haq S. M.
    Soliman. Synthesis, Structure and antimicrobial activity of a new 2D silver(I)
    coordination polymer with 2-pyridone ligands. Applied Sciences, 2020, 10, 4853.
  168. M. Al-Qubati, H. A. Ghabbour, S. M. Solimand, A. M. Al-Majid, A. Barakat, Mujeeb A. Sultan. Synthesis of N-(Anthracen-9-ylmethyl)-N-methyl-2-(phenylsulfonyl)ethanamine Via Microwave Green Synthesis Method: X-Ray Characterization, DFT and Hirshfeld Analysis. Crystals 2020, 10(8), 643.
  169. A. M. Al-Majid, S.M. Soliman, M. Haukka, M. Ali, M.S. Islam, M.R. Shaik and A. Barakat, Design, Construction, and Characterization of a New Regioisomer and Diastereomer Material Based on the Spirooxindole Scaffold Incorporating Sulphone Function. Symmetry, 2020, 12, 1337.
  170. A. Barakat, S. Alshahrani, A. M. Al-Majid, M. Ali, Mezna S. Altowyan, M. S. Islam, A. S. Alamary, and S. Ashraf and Z. Ul-Haq. Synthesis of a New Class of Spiroxindole- embedded Benzo[b]Thiophene Based Molecules as Cholinesterase Inhibitors. Molecules, 2020, 25(20), 4671.
  171. Mujeeb A. Sultan, Mansour S. A. Galil, Mohyeddine Al-Qubati, Abdullah Mohammed Al-Majid, A. Barakat, Microwave-Assisted Regioselective Synthesis of Substituted-9-bromo-9,10-dihydro-9,10-ethanoanthracenes Via Diels-Alder Cycloaddition. Journal of King Saud University of sciences, 2020,  32)8(, 3417-3420.
  172. S. Alshahrani, S. M. Soliman, A. S. Alamary, A. M. Al-Majid, Matti Haukka, S. Yousuf and A.Barakat. Synthesis of Enaminones Based Benzo[d]imidazole Scaffold: Characterization and Molecular Insight Structure. Crystals 2020, 10(10), 955.
  173. Mujeeb A. Sultan,Mansour S. A. Galil, Mohyeddine Al-Qubati, Mufeed M. Omar, and Assem Barakat, Synthesis, Molecular Docking, Druglikeness Analysis and ADMET Prediction of the Chlorinated Ethanoanthracene Derivatives as Possible Antidepressant Agents. Applied Sciences, 2020, 10(21), 7727.
  174. Sajjad Haider, Assem Barakat and Zaheer Ul-Haq. Discovery of Potential Chemical Probe as Inhibitors of CXCL12 Using Ligand-Based Virtual Screening and Molecular Dynamic Simulation. Molecules, 2020, 25(20), 4829.
  175. Ahmed A. M. Sarhan, Matti Haukka, Assem Barakat, Ahmed Boraei, A new synthetic approach to β-enyl-pyran-2,4-dione via microwave assisted one-pot dimerization cyclization and expeditious regioselective conversion into β-enamino-pyran-2,4-diones. Tetrahedron letters. 2020, 61(52), 152660.
  176. A.T. A. Boraei, S. M. Soliman, M. Haukka, and A. Barakat.Synthesis of two new hits of triazolyl-indole bearing sulfanyl moiety: X-ray structure, Hirshfeld analysis, and DFT studies. Journal of Molecular Structure, 2021, 1225, 129302.
  177. A.T. A. Boraei, M. Haukka, S. M. Soliman, and A. Barakat. Synthesis, X-Ray Structure, Tautomerism Aspect, and Chemical Insight of the 3-(1H-Indol-2-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-6-ol. Journal of Molecular Structure, 2021, 1227, 129429.
  178. A. M. Al-Majid, M. Haukka, S. M. Soliman, A. S. Alamary, S. Alshahrani, M. Ali, M. S.Islam, A. Barakat, X-ray Crystal Structure and Hirshfeld Analysis of Gem-Aminals-Based Morpholine, Pyrrolidine, and Piperidine Moieties. Symmetry, 2021, 13(1), 20.
  179. Y. M. Abdel Aziz, G. Lotfy, M.M. Said, El Sayed H. El Ashry,El Sayed H. El Tamany,Matti Haukka and A. Barakat. Synthesis and characterization of a new spirooxindole grafted pyrrolidino/piperidine moiety. Record of pharmaceutical and biomedical sciences, 2021, 5, 1-7.
  180. A. H. M. Hussein, A. A. Khames, Abu-Bakr A. El-Adasy, A. A. Atalla, M.Abdel-Rady , M. I. A. Hassan, M. A. Abou-Salim, Y. A. A. M. Elshaier  and A. Barakat. Multifunctional Isosteric Pyridine Analogs-Based 2-Aminothiazole: Design, Synthesis, and Potential Phosphodiesterase-5 Inhibitory Activity. Molecules, 2021, 26, 902.
  181. A. Mohammed Al-Majid, S. M. Soliman, H. A. Ghabbour, M. Ali, M.S.Islam, M.R. Shaik and A. Barakat. Synthesis and X-Ray Crystal Structure of Unexpected Novel Thiazolidinone/1,3,4-Thiadiazole Heterocycle via S-Alkylation and Smiles Rearrangement Dual Approaches. Journal of Molecular Structure, 2021, 1234, 130156.
  182. M. S. Islam, M. Ali, A. M. Al-Majid, A. S. Alamary, S. AlShahrani, S.Yousuf,M. Iqbal Choudhary , and A. Barakat.Bimetallic Iron–Palladium Catalyst System as a Lewis-Acid for the Synthesis of Novel Pharmacophores Based Indole Scaffold as Anticancer Agents. Molecules, 2021, 26(8), 2212.
  183. N. N. E. El-Sayed, T. M. Al-Otaibi, M. A.
    Alonazi, Vijay H. Masand, A. Barakat, Z. M. Almarhoon, A. A Ben
    Bacha. Synthesis and characterization of some new quinoxalin-2(1H)one
    and 2-methyl-3H-quinazolin-4-one derivatives targeting the onset and
    progression of CRC. Molecules, 2021, 26(11), 3121.
  184. A. Barakat, A. El-Faham, M. Haukka, A. M. Al-Majid, S. M. Soliman. s-Triazine pincer ligands: Synthesis of their metal complexes, coordination behavior, and applications. Appl. Organomet. Chem. 2021; e6317.
  185. A. Barakat. M. S. Islam, M. Ali, A. M. Al-Majid, S. AlShahrani, A. S. Alamary, S.Yousuf, M. Iqbal Choudhary, Regio- and Stereoselective Synthesis of a New Series of Spirooxindole Pyrrolidine Grafted Thiochromene Scaffolds as Potential Anticancer Agents. Symmetry, 2021, 13(8), 1426.
  186. N.Salahuddin, M. Ali, M.Ayad, A. Barakat, H. A. Al-Lohedan, Z. A. Issa. Aniline-co-o-anthranilic acid copolymer-chitosan/Ag@AgCl nanohybrid as a carrier for (E)-N'-(pyridin-2-ylmethylene) hydrazinecarbothiohydrazide Release and antimicrobial activity. ACS Omega, 2021, 6, 34, 21939–21951.
  187. A.T. A. Boraei, M. Haukka, A. A.M. Sarhan, S. M. Soliman, A. Barakat. Intramolecular Hydrogen Bond, Hirshfeld Analysis, AIM; DFT studies of Pyran-2,4-dione Derivatives. Crystals, 2021, 11(8), 896.
  188. A.T. A. Boraei, M. Haukka, A. A.M. Sarhan, S. M. Soliman, A.M.Al-Majid, A. Barakat. Synthesis and X-Ray Crystal Structure of New Substituted 3-4´-Bipyrazole Derivatives. Hirshfeld Analysis, DFT and NBO Studies. Crystals, 2021, 11(8), p.953.
  189. A.T. A. Boraei, S. M. Soliman, M. Haukka, El Sayed H. El Tamany, A.M.Al-Majid, A. Barakat. X-Ray Single Crystal Analysis, Tautomerism Aspect, DFT, NBO, and Hirshfeld Surface Analysis of a New Schiff Bases Based on 4-Amino-5-indol-2-yl-1,2,4-triazole-3-thione Hybrid. Crystals, 2021, 11, 1041.
  190. A.T. A. Boraei, M. Haukka, A. A.M. Sarhan, S. M. Soliman, A.M.Al-Majid, A. Barakat. Synthesis of bis(β-Enamino-Pyran-2,4-dione) Derivative Linked via 1,6-Hexylene Spacer: X-Ray Crystal Structures, Hishfeld studies and DFT calculations of Mono- and Bis(Pyran-2,4-diones) Derivatives. Symmetry, 2021, 13(9), 1646.
  191. Altowyan, Mezna S., M. A. Sultan, S. M. Soliman, S. Yousuf, I. Ali, I. Shawish, and A. Barakat. Synthesis, Single Crystal X-ray, Hirshfeld and DFT Studies of 1,8-Dichloro-9,10-dihydro-9,10-ethanoanthracene-11-carboxylic Acid. Crystals 2021, 11, no. 10: 1161. 
  192. A. Barakat, A. M. Al-Majid, G. Elarag, M. Ali, A. Mostafa, Y.A. M. M. Elshaier. Drug repurposing of lactoferrin combination in a nano-drug delivery system to combat severe acute respiratory syndrome coronavirus 2 infection. Dr. Sulaiman Al Habib Medical Journal, 2021, 3(3)-101-112.
  193. A. M. Al-Majid, M. Ali, M. S. Islam, S. AlShahrani, A. S. Alamary, S.Yousuf, M. Iqbal Choudhary , and A. Barakat. Stereoselective Synthesis of the Di-Spirooxindole Analogs Based Oxindole and Cyclohexanone Moieties as Potential Anticancer Agents. Molecules, 2021, 26(20), 6305.
  194. M. A. M. Abu-Youssef, V. Langer, ِA. Barakat, M.
    Haukka, S. M. Soliman. Molecular, Supramolecular structures combined with Hirshfeld and DFT studies of Centrosymmetric M(II)-azido {M=Ni(II), Fe(II) or Zn(II)} complexes of 4-benzoylpyridine. Symmetry, 2021, 13(11), 2026
  195. A.S. Alamary, A. M. Al-Majid, A. Barakat, S. Alshahrani, M. Ali, M. S. Islam. Asymmetric Henry Reaction of Nitromethane with substituted aldehydes Catalyzed by novel Chiral bis(β-aminoalcohol-Cu(OAc)2.H2O Complex. Catalysts 2021, 11(10), 1208.
  196. G. Lotfy, Y.M. Abdel Aziz, M. M. Said, El Sayed H. El Ashry, El Sayed H. El Tamany,M. M. Abu-Serie, M. Teleb,  A. Dömling, A. Barakat. Inspirational design and facial synthesis of novel hybrid spirooxindoles-based p53-MDM2 inhibitors endowed with Bcl2 signaling attenuation; a step towards the next generation p53 activators. Bioorganic. Chem. 2021, 117, 105427.
  197. Y. M. Abdel Aziz,G. Lotfy, M. M. Said, El Sayed H. El Ashry, El Sayed H. El Tamany, Marwa M. Abu-Serie, Mohamed Teleb, S. M. Soliman, S. Yousuf, A. Dömling, Luis R. Domingo, and A. Barakat. Design, Synthesis, Chemical and Biochemical Insights onto Novel Hybrid Spirooxindoles-Based p53-MDM2 Inhibitors with Potential Bcl2 Signaling Attenuation. Front. Chem.-Supramol. Chem 2021, 9, 735236.
  198. M. S. Islam, Abdullah M. Al-Majid, M. Azam, Ved Prakash Verma, A. Barakat, M. Haukka, A. A. Elgazar, Amira Mira, Farid A. Badria. Construction of spirooxindole analogs engrafted with indole and pyrazole scaffolds as acetylcholineesterase inhibitors. ACS Omega 2021, 6, 31539−31556.
  199. A. Barakat, M. Haukka, S. M. Soliman, M. Ali, A.
    M.Al-Majid, A. El-Faham. Luis R. Domingo. Straightforward Regio- and Diastereoselective Synthesis, Molecular Structure, Intermolecular Interactions and Mechanistic Study of Spirooxindole Engrafted Rhodanine Analogue. Molecules, 2021, 26, 7276.
  200. M. S. Islam, A. S. Alamary, A. Barakat, S. Alshahrani, M. Haukka, A. M. Al-Majid, Exploiting the Chiral Ligands of Bis(imidazolinyl)- and Bis(oxazolinyl)thiophenes - Synthesis and Application in Cu-Catalyzed Friedel-Crafts Asymmetric Alkylation. Molecules 2021, 26(23), 7408.
  201. M. S. Islam, Abdullah M. Al-Majid, M. Azam, Ved Prakash Verma,A. Barakat, M. Haukka, Luis R. Domingo. A. A. Elgazar, Amira Mira, Farid A. Badria. Synthesis of spirooxindole analogs tethered pyrazole scaffold as acetylcholinesterase inhibitors. ChemistrySelect, 2021, 6, 1– 16.
  202. I. Shawish, S. M. Soliman, M. Haukka, A. Dalbahi, A. Barakat, A. El-Faham. Synthesis, and Molecular Structure Investigations of a New s-Triazine Derivatives Incorporating Pyrazole/Piperidine/ Aniline Moieties. Crystals, 2021, 11, 1500.
  203. M.S. Islam, M. Haukka, S. M. Soliman, A. M.Al-Majid, A.F.M. Motiur Rahman, A. Bari, A. Barakat, Regio- and Stereoselective Synthesis of Spiroheterocyclyes Bearing the Pyrazol Scaffold via [3+2] Cycloaddition Reaction. Journal of Molecular Structure, 2022, 1250, 131711. 
  204. M. S. Altowyan, S. M. Soliman,M. Haukka, N. H. Al-Shaalan, A. A. Aminah, A. Barakat.[3+2] Cycloaddition Protocol for the Stereoselective Synthesis for Designed a New Spirooxindole Compound Grafted Imidazo[2,1-b]thiazole Scaffold: Crystal Structure and Computational Study. Crystals, 2022, 12(1), 5.
  205. M. S. Altowyan, S. M. Soliman,M. Haukka, N. H. Al-Shaalan, A. A Aminah, A. Barakat.Synthesis of Unexpected Dimethyl 2-(4-chlorophenyl)-2,3-dihydropyrrolo[2,1-a]isoquinoline-1,3-dicarboxylate via Hydrolysis/Cycloaddition/Elimination Cascades: Single Crystal X-Ray and Chemical Structure Insights. Crystals, 2022, 12(1), 6.
  206. M. S. Altowyan, S. M. Soliman, M. M. F. Ismail, M.
    Haukka,     ِA. Barakat, M. S. Ayoup. Efficient Consecutive Synthesis of Ethyl 2-(4-aminophenoxy) acetate, a
    Precursor for Dual GK and PPARγ Activators, X-Ray Structure, Hirshfeld
    Analysis and DFT Studies
    Crystals 2022, 12(2), 227
  207. E. M. Fathallas, Jörg H. Albering, M. S. Altowyan, A. Barakat, M. A. M. Abu-Youssef, S. M. Soliman, A. M. A. Badr. Synthesis, X-ray structure, Hirshfeld, DFT and biological studies of the quinazolinone-nitrate as a proton transfer complex. Molecules 2022, 27(3), 1089.
  208. A. T. A. Boraei, S.M. Soliman, M. Haukka, E. E. Sallama, M. Sopaih, A.Barakat, A. A. M. Sarhan. Straightforward green synthesis of Indeno-furan carboxylates from ninhydrin and β-ketoesters: X-ray crystal structure, Hirshfeld and DFT investigations. Journal of Molecular Structure, 2022,1255, 132433.
  209. A. T. A. Boraei, M. Haukka, M. Sopaih, A. M. Al-Majid, ِA. Barakat, A. A. M. Sarhan Straightforward One-Pot Synthesis of New 4-Phenyl-1,2,5,6-tetraazafluoranthen-3(2H)-one Derivatives: X-ray Single Crystal Structure and Hirshfeld Analyses. Crystals, 2022, 12(2), 262. 
  210. A. M. Al-Majid, A. S. Alamary, S. Alshahrani, M. Haukka, M. S. Islam, A. Barakat, Cu(II)-thiophene-2,5-bis(amino-alcohol) mediated asymmetric Aldol reaction and Domino Knoevenagel Michael cyclization: a new highly efficient Lewis acid catalyst. RSC Adv., 2022, 12, 6149–6165
  211. A. Barakat, M. Haukka, S. M. Soliman, A. M. Al-Majid, M. Ali, M. Shahidul Islam, A.M.Karami, Z. Ul-Haq, L. R. Domingo. Synthesis and anti-cancer activity of a new hybrid based spirooxindole-pyrrolidine -thiochromene scaffolds via [3+2] cycloaddition reaction: Computational investigation. Polycyclic Aromatic Compounds, 2022, https://doi.org/10.1080/10406638.2022.2042334
  212. M. S. Altowyan, S. M. Soliman, J. Lasri, N. E. Eltayeb, M. Haukka, A. Barakat and A. El Faham. A new Pt(II) complex with anionic s-triazine based NNO-donor ligand: Synthesis, X-ray structure, Hirshfeld analysis and DFT studies. Molecules, 2022, 27(5), 1628.
  213. Mezna Saleh Altowyan, Mostafa A. El-Naggar, Morsy A. M. Abu-Youssef, Saied M. Soliman, Matti Haukka, A. Barakat and Ahmed M. A. Badr. Synthesis, X-ray Structure, Antimicrobial and Anticancer Activity of a Novel [Ag(ethyl-3-quinolate)2(citrate)] Complex. Crystals, 2022, 12, 356.
  214. M. S. Altowyan, N. H. Al-Shaalan, A. A. Alkharboush, A. Barakat, S. M. Soliman. Synthesis, Molecular and Supramolecular Structure Aspects, and Antimicrobial Activity of the Centrosymmetric [Ag(5-Nitroquinoline)2]ClO4 Complex. Symmetry 2022, 14(3), 547.
  215. A.M. Farghaly, Ola H. Rizk, I. Darwish, M. Hamza, M. S. Altowyan, A. Barakat, M. Teleb. Design, Synthesis, Pharmacodynamic and In silico Pharmacokinetic Evaluation of Some Novel Biginelli-derived Pyrimidines and Fused Pyrimidines as Calcium Channel Blockers. Molecules 2022, 27(7), 2240.
  216. M.A. El-Naggar, Jörg H. Albering, A. Barakat, M. A. M. Abu-Youssef, S. M. Soliman, Ahmed M. A. Badr. New bioactive 1D Ag(I) coordination polymers with pyrazole and triazine ligands; Synthesis, X-ray structure, Hirshfeld analysis and DFT studies. Inorganica Chimica Acta 2022, 537,  120948.
  217. M. N. Abd Al Moaty, El Sayed H. El Ashry, L. F. Awad, N. A. Ibrahim, M. M. Abu-Serie, A. Barakat, M. S. Altowyan and M. Teleb. Enhancing the anticancer potential of targeting tumor-associated metalloenzymes via VEGFR inhibition by new triazolo[4,3-a]pyrimidinone acyclo C-nucleosides multitarget agents. Molecules 2022, 27(8), 2422.
  218. M. A. El-Naggar, M. A. M. Abu-Youssef, S. M. Soliman, M. Haukka, A. M. Al-Majid, A. Barakat and A. M. A. Badr. Synthesis, X-ray Structure, Hirshfeld, and Antimirobial studies of new Ag(I) Complexes based on pyridine-Type ligands. Journal of Molecular structure 2022, 1264, 133210. 
  219. Mar Ríos-Gutiérrez, A. Barakat, and Luis R. Domingo. A Molecular Electron Density Theory Study of the pmr-type [3+2] Cycloaddition Reaction of Azomethine Ylides Derived from Isatins and L-Proline with Phenyl Vinyl Sulphone. Organics, 2022, 3(2), 122-136.
  220. M. S. Altowyan, E.M. Fathalla, J. H. Albering, A. Barakat, M. A. M. Abu-Youssef, S.M. Soliman, T. S. Kassem, A. M. A. Badr. Synthesis, X-ray, Hirshfeld, and AIM Studies on Zn(II) and Cd(II) Complexes with Pyridine Ligands. Crystals 2022, 12, 590.
  221. H. A. Elbadawy, S. M. S. M. Khalil, D.Al-Wahaib, A. Barakat, S. M. Soliman, Ali Eldissouky. Ag(I)-mediated hydrolysis of hydrazone to azine; synthesis, X-ray structure, and biological investigations of two new Ag(I)-azine complexes. Appl Organomet Chem. 2022; e6757.
  222. A. Khan, S.A.Khan, K. Zia, M. S. Altowyan, A. Barakat, and Z. Ul-Haq. Deciphering the impact of mutations on binding efficacy of SARS-CoV-2 Omicron and Delta variants with human ACE2 receptor. Front. Chem. 10:892093. doi: 10.3389/fchem.2022.892093
  223. T. E. Khalil, S. M. Soliman, N. A. Khalil, S. Foro and A. El-Dissouky M. Ali, A. Barakat, Synthesis of unexpected [Mn(2-(1-hydrazonoethyl)pyridine)Cl2]n 1D coordination polymer via self-assembly of 1-(pyridin-2-yl)ethylidene)hydrazono)methyl)phenol with MnCl2; X-ray crystal structural analysis and biological studies. Appl Organomet Chem. 2022, minor revision. 
  224. Y. A. A. M. Elshaier, M. T. M. Nemr, M. S. Refaey, W. A. A. Fadaly, A. Barakat. Chemistry of 2-Vinylindoles: Synthesis and Applications. New Journal Chemistry 2022, 46, 13383 – 13400.
  225. M. S. Altowyan, S. M. Soliman, M. Haukka, N. Hamad
    Al-Shaalan, A. A. Alkharboush, A. Barakat. Synthesis and Structure Elucidation of Novel Spirooxindole Linked to
    Ferrocene and Triazole Systems via [3+2] Cycloaddition Reaction. Molecules, 2022, 27(13), 4095.
  226. M. S. Altowyan, S. M. S. M. Khalil, D. Al-Wahaib, A.
    Barakat, S. Soliman, A. E. Ali, H. A. Elbadawy. Synthesis of a novel unexpected Cu(II) thiazolidine complex; X-ray structure, Hirshfeld surface analysis, and biological studies. Molecules, 2022, 27, 4583.
  227. I. Shawish, A. Barakat, A. Dalbahi, A. M. Malebari, M. S. Nafie, A. A. Bekhit, A. Albohy, A. Khan, Z.Ul-Haq, M. Haukka,  B. G. de la Torre, F. Albericio, A. El-Faham. Synthesis and antiproliferative activity of a new series of mono- and bis-(dimethylpyrazolyl)-s-triazine derivatives targeting EGFR/PI3K/AKT/mTOR signaling cascades. ACS Omega, 2022, 7(28):24858-24870.
  228. M. S. Altowyan, S. M. Soliman, M. M. F. Ismail, M.
    Haukka,     A. Barakat, M.S. Ayoup. New Bioprecursor Prodrugs of Sulfadiazine: Synthesis, X-Ray structure and Hirshfeld Analysis. Crystals, 2022, 12(8), 1016.
  229. A. Barakat, M.M. Abu-Serie, M. Ali, A. Mohammed Al-Majid, S. Ashraf, K. Zia, Z. Ul-Haq, A. Al-Dhfyan, H.A. Abdel-Aziz, A. El-Fahamand L.R. Domingo. Synthesis, in vitro and in cell study of a new spirooxindoles based N-alkylated maleimides targeting HER2/3 signaling pathway. Polycyclic aromatic compounds, 2022, DOI: 10.1080/10406638.2022.2101486.
  230. I. Shawish, A. Barakat, A. Dalbahi, W. Alshaer, F.Daoud, D. A. Alqudah, M. Al Zoubi, M.M. Hatmal, M. S. Nafie, M. Haukka, A. Sharma, B. G. de la Torre , F. Albericio, A. El-Faham. Acetic acid mediated for one-pot synthesis of novel pyrazolyl s-triazine derivatives for the targeted therapy of triple-negative breast carcinoma via EGFR/PI3K/AKT/mTOR signaling cascades. Pharmaceutics 2022, 14(8), 1558.
  231. M. S. Islam, A.M.Al-Majid, E. N. Sholkamy, S. Yousuf, M. Ayaz, A.Nawaz, A. Wadood, A. Ur Rehman, Ved Prakash Verma,  A. Bari, M. Haukka, S.M. Soliman and A. Barakat. Synthesis, molecular docking and enzyme ihibitory approaches of some new chalcones engrafted pyrazole as potential antialzheimer, antidiabetic and antioxidant agents. Journal of Molecular Structure, 2022, 1269, 133843
  232. M. S. Altowyan, S. M. Soliman, M. Haukka, N. Hamad
    Al-Shaalan, A. A. Alkharboush, A. Barakat.     Synthesis, Characterization, and Cytotoxicity of New Spirooxindoles Engrafted Furan Structural Motif as Potential Anti-cancer agent. ACS Omega, 2022, 7, 40, 35743–35754.
  233. A. Barakat, S. Alshahrani, A. M. Al-Majid, A. S. Alamary, M. Haukka, M. M. Abu-Serie, A.Dömling, F. F. El-Senduny, E. A. Mazyed, F. A. Badria. Novel spirooxindole based benzimidazole scaffold: In vitro, nanoformulation and in vivo studies on anticancer and antimetastatic activity of breast adenocarcinoma. Bioorg. Chem. 2022, 129, 106124. 
  234. M. Islam, A.Al-Majid, E.Sholkamy, S. Yousuf, M. Ayaz, A.Nawaz, A. Wadood, A. Rehman, Ved Prakash Verma, F. Rahman and A. Barakat. Synthesis of spiro-oxindole analogs engrafted pyrazole scaffold as potential Alzheimer's disease therapeutics: Anti-oxidant, Enzyme inhibitory and molecular docking approaches. ChemistrySelect 2022, 7(36), p.e202203047.
  235. A. Barakat, A. Mostafa, M. Ali, A.A. Al-Majid, L.R.Domingo, O. Kutkat, Y. Moatasim, Y. Elshaier, Design, synthesis and in vitro evaluation of spirooxindole-based phenylsulphonyl moiety as a candidate anti-SAR-CoV-2 and MERS-CoV-2 with implementation of combination therapy. International journal of molecular sciences, 2022, 23(19), p.11861.
  236. S. Ali Khan, A. Khan, K. Zia 1, I. Shawish, A. Barakat, and Z. Ul-Haq. Cheminformatics-Based Discovery of Potential Chemical Probe Inhibitors of Omicron Spike Protein. International Journal of Molecular Sciences. 2022; 23(18):10315.
  237. Shawish, I., Aldalbahi, A., Al-Rasheed, H.H., Ali, M., Alshaer, W., Al Zoubi, M., Al Ayoubi, S., De La Torre, B.G., Albericio, F. and El-Faham, A., Pyrazolyl-s-triazine with indole motif as a novel of epidermal growth factor receptor/cyclin-dependent kinase 2 dual inhibitors. Frontiers in Chemistry, 2022, p.1467.
  238. Altowyan, M.S., Soliman, S.M., Al-Wahaib, D., Barakat, A., Ali, A.E. and Elbadawy, H.A., Synthesis of a New Dinuclear Ag (I) Complex with Asymmetric Azine Type Ligand: X-ray Structure and Biological Studies. Inorganics, 2022, 10(11), p.209.
  239. Altowyan, M.S., Soliman, S.M., Al-Wahaib, D., Barakat, A., Ali, A.E. and Elbadawy, H.A., Synthesis of a New Ag (I)-Azine Complex via Ag (I)-Mediated Hydrolysis of 2-(((1-(Pyridin-2-yl) ethylidene) hydrazineylidene) Methyl) phenol with AgClO4; X-ray Crystal Structure and Biological Studies. Symmetry, 2022, 14(11), p.2226.
  240. Al-Rasheed, H.H.; Al-Majid, A.M.; Ali, M.; Haukka, M.; Ramadan, S.; Soliman, S.M.; El-Faham, A.; Domingo, L.R.; Barakat, A. [3 + 2] Cycloadditions in Asymmetric Synthesis of Spirooxindole Hybrids Linked to Triazole and Ferrocene Units: X-ray Crystal Structure and MEDT Study of the Reaction Mechanism. Symmetry 2022, 14, 2071.
  241. Domingo, L.R.; Ríos-Gutiérrez, M.; Barakat, A. A Molecular Electron Density Theory Study of the [3+2] Cycloaddition Reaction of an Azomethine Ylide with an Electrophilic Ethylene Linked to Triazole and Ferrocene Units. Molecules 2022, 27, 6532.
  242. Al-Rasheed, H.H.; Haukka, M.; Soliman, S.M.; Al-Majid, A.M.; Ali, M.; El-Faham, A.; Barakat, A. Synthesis and Solid-State X-ray Structure of the Mononuclear Palladium(II) Complex Based on 1,2,3-Triazole Ligand. Crystals 2022, 12, 1335.
  243. Altowyan, M.S.; Albering, J.H.; Barakat, A.; Soliman, S.M.; Abu-Youssef, M.A.M. Synthesis, Supramolecular Structural Investigations of Co(II) and Cu(II) Azido Complexes with Pyridine-Type Ligands. Crystals 2023, 13, 346.
  244. Altowyan, M.S.; Haukka, M.; Soliman, S.M.; Barakat, A.; Alaswad, S.O.; Boraei, A.T.A.; Gad, E.M.; Youssef, M.F. Synthesis, Characterization and Single Crystal X-ray Diffraction Analysis of Fused Triazolo/Thiadiazole Clubbed with Indole Scaffold. Crystals 2023, 13, 423.
  245. Altowyan, M.S.; Haukka, M.; Soliman, S.M.; Barakat, A.; Boraei, A.T.A.; Sopaih, M. Synthesis of a Novel Hydrazone of Thieno[2,3-d]pyrimidine Clubbed with Ninhydrin: X-ray Crystal Structure and Computational Investigations. Crystals 2023, 13, 384.
  246. Al-Rasheed, H.H.; AL-khamis, S.A.; Barakat, A.; El-Faham, A.; Haukka, M.; Soliman, S.M. Synthesis and Characterizations of Novel Isatin-s-Triazine Hydrazone Derivatives; X-ray Structure, Hirshfeld Analysis and DFT Calculations. Crystals 2023, 13, 305.
  247. Altowyan, M.S.; Fathalla, E.M.; Albering, J.H.; Barakat, A.; Abu-Youssef, M.A.M.; Soliman, S.M.; Badr, A.M.A. Synthesis, Molecular, and Supramolecular Structures of Two Azide-Bridged Cd(II) and Cu(II) Coordination Polymers. Symmetry 2023, 15, 619.
  248. Alshahrani, S.; Al-Majid, A.M.; Ali, M.; Alamary, A.S.; Abu-Serie, M.M.; Dömling, A.; Shafiq, M.; Ul-Haq, Z.; Barakat, A. Rational Design, Synthesis, Separation, and Characterization of New Spiroxindoles Combined with Benzimidazole Scaffold as an MDM2 Inhibitor. Separations 2023, 10, 225.
  249. M. S. Islam, A.M.Al-Majid, E. N. Sholkamy, A. Barakat,  M. Viale, P. Menichini, A. Speciale, F. Loiacono, V. P. Verma,  S. Yousuf, M.Teleb. Optimized spirooxindole-pyrazole hybrids targeting the p53-MDM2 interplay induce apoptosis and synergize with doxorubicin in A549 cells. Scientific reports 2023, 13, 7441.
  250. E. M. Fathalla, M. A. M. Abu-Youssef, M. M. Sharaf, A.
    El-Faham, A. Barakat, M. Haukka, S. M. Soliman. Synthesis, X-ray structure of two hexa-coordinated Ni(II) complexes with s-triazine hydrazine Schiff base ligand. Inorganics,     2023, 11(5), 222.
  251. M. S.Altowyan, M. Haukka, S. M. Soliman, A. Barakat, A. T. A. Boraei and A. Aboelmagd. Stereoselective Synthesis of New 4-Aryl-5-indolyl-1,2,4-triazole S-and N-β-Galactosides: Characterizations, X-Ray Crystal Structure and Hirshfeld Surface Analysis. Crystals 2023, 13(5), 797.
  252. A. Yousri, A. El-Faham, M. Haukka, M. S. Ayoup, M. M. F. Ismail, N. G. El Menofy, S. M. Soliman, L. Öhrström, A.Barakat, M.A. M. Abu-Youssef. A Novel Na(I) Coordination Complex with s-Triazine Pincer Ligand: Synthesis, X-Ray structure, Hirshfeld Analysis, and Antimicrobial Activity. Crystals 2023, 13(6), 890.
  253. E. M. Fathalla, M. A. M. Abu-Youssef, M. M. Sharaf, A. El-Faham, A. Barakat, A.M. A. Badr, S. M. Soliman,A. M.Z.Slawin, J. D. Woollins. Synthesis, Characterizations, Antitumor and Antimicrobial Evaluations of Novel Mn(II) and Cu(II) Complexes with NNN-tridentate s-Triazine-Schiff base Ligand. Inorganica Chimica Acta, 2023, 555, 121586.
  254. R. M. Al-Jassas, M. S. Islam, A. M.Al-Majid, M. S. Nafie, M. Haukka, A.F.M. Motiur Rahman, A. A. Alayyaf, and A. Barakat. Synthesis and SARs study of novel spiro-oxindoles as potent antiproliferative agents with CDK2 inhibitory activities, Archiv der Pharmazie 2023, e2300185.
  255. E. M. Fathalla, M. A. M. Abu-Youssef, M. M. Sharaf, A.
    El-Faham, A. Barakat, M.Haukka, S. M. Soliman. Supramolecular Structure and Antimicrobial Activity of Ni(II) Complexes with s-Triazine/Hydrazine Type Ligand. Inorganics, 2023, 11(6), 253.
  256. A.Yousry, M. Haukka, M. A. M. Abu-Youssef, M. S. Ayoup, M. M. F.Ismail, N. G. El Menofy, S. M. Soliman, A. Barakat, F. M. Amombo Noa, L. Öhrström. Synthesis, Structure diversity, and Antimicrobial Studies of Ag(I)Complexes with Quinoline-type Ligands. CrystEngComm, 2023, 25, 3922-3930.
  257. E. E. Salama, M. F. Youssef, A. T. A. Boraei, M. Haukka, S. M. Soliman, A. Barakat, A. A. M. Sarhan. Base-Controlled Regiospecific Mono- and Diallylation of 4-Aryl-5-indolyl-1,2,4-triazole-3-thione: Thio-Aza Allyl Rearrangement. Crystals 2023, 13(7), 992.
  258. S. M. Soliman, E. M. Fathalla, M. M. Sharaf, A. El-Faham, A. Barakat, M. Haukka, A. M.Z.Slawin, J. Derek Woollins, M. A. M. Abu-Youssef. Synthesis, Structure and Antimicrobial Activity of New Co(II) Complex with bis-Morpholino/Benzoimidazole -s-Triazine Ligand. Inorganics, 2023, 11(7), 278.
  259. M. S. Islam,A. M. Al-Majid,M.Haukka,Z. Parveen,N. Ravaiz,A. Wadood,A. Ur Rehman,Mar Ríos-Gutiérrez, L. R. Domingo,A. Barakat. A Novel Alpha Amylase Inhibitor Based Spirooxindole-Pyrrolidine- Clubbed Thiochromene-Pyrzaole Pharmacophores:  Unveiling the [3+2] Cycloaddition Reaction by Molecular Electron Density Theory. Chemical Biology & Drug Design, 2023, 00:1–24.
  260. A. T. A. Boraei, El. H. Eltamany, M. Haukka, S. M. Soliman, A. Barakat, M. Sopaih. Synthesis and X-Ray Crystal Structure Analysis of Substituted 1,2,4-Triazolo[4',3':2,3]pyridazino[4,5-b]indole and its Precursor. Crystals 2023, 13(7), 1036.
  261. S. Alshahrani, A. M. Al-Majid, A. S. Alamary, Mar Rìos-Gutiérrez, A. Barakat. Exploring Regio- and Stereoselectivity in [3+2] Cycloaddition: Molecular Electron Density Theory Approach for Novel Spirooxindole-Based Benzimidazole with Pyridine Spacer. Crystals 2023, 13(7), 1085
  262. M. A. El-Naggar, M. A. M. Abu-Youssef, M. Haukka, A. Barakat, Mona M. Sharaf, S. M. Soliman. Synthesis, X-ray Structure and Hirshfeld Analysis of [Ag(3-amino-5,6-dimethyl-1,2,4-triazine)(NO3)]n; A Potent Anticancer and Antimicrobial Agent. Inorganics 2023, 11, 350.
  263. E. M. Hassan, S. M. Soliman, E. A. Moneer, M. Hagar, A. Barakat, M. Haukka, H. Rasheed. Synthesis, X-ray structure, Hirshfeld, DFT conformational, Cytotoxic, and Anti-toxoplasma and studies of new indole-hydrazone derivatives. Int. J. Mol. Sci. 2023, 24, 13251.
  264. M. S. Ayoup, Y. Wahby, H. Abdel-Hamid, M. M. Abu-Serie, S.Ramadan, A.Barakat, Mohamed Teleb and M. M. F. Ismail. Reinvestigation of Passerini and Ugi scaffolds as multistep apoptotic inducers via dual modulation of caspase 3/7 and p53-MDM2 signaling for halting breast cancer. RSC Advances 2023, 13(40):27722-27737.
  265. H. H. Al-Rasheed, S. A. AL-khamis, A. El-Faham, A.
    Barakat, A. M.Z.Slawin, J. D. Woollins, S. M. Soliman. Synthesis, X-ray Structure, Hirshfeld Surface Analysis and
    Antimicrobial Assessment of Tetranuclear s-Triazine Hydrazine Schiff Base
    Ligand.     Inorganics 2023, 11(9), 357.
  266.  M. S. Altowyan, M. Haukka, M. S. Ayoup, M. M. F. Ismail, N. G. El Menofy, S. M. Soliman, A. Barakat, M. M. Sharaf, M. A. M. Abu-Youssef, A.Yousri. Synthesis, Crystal Structure Analyses, and Antibacterial evaluation of
    the Cobalt(II) Complex with Sulfadiazine-Pyrazole Prodrug.     Inorganics 2023, 11(10), 382.
  267. N. N. Eid El-Sayed, T. M. Al-Otaibi, A. Barakat, Z. M. Almarhoon, M.Z. Hassan, M. I. Al-Zaben, A. Ben Bacha. Synthesis and biological evaluation of some new
    3-aryl-2-thioxo-2,3-dihydroquinazolin-4(1H)-ones and 3-aryl-2-(benzylthio)
    quinazolin-4(3H)-ones as antioxidants, COX-2, LDHA, α-glucosidase and
    α-amylase inhibitors, as well as anti-colon carcinoma and apop    tosis inducing agents. Pharmaceuticals, 2023, 16(10), 1392.
  268. S. Alshahrani, A. M. Al-Majid, A. S. Alamary, M. Ali, M. S. Altowyan, M. Ríos-Gutiérrez, S. Yousuf, A. Barakat. Synthesis and Characterization of New Spirooxindoles Including Triazole and Benzimidazole Pharmacophores by [3+2] cycloaddition reaction: A MEDT Study of the Mechanism and Selectivity. Molecules 2023, 28(19), 6976.
  269. M. S. Altowyan, A. Yousri, J. H. Albering, R. C. Fischer, M.A. M. Abu-Youssef, M. S. Ayoup, A. Barakat, S.M. Soliman. A New Zn(II) Azido Complex of L-Arginine: X-ray Crystal Structure, Hirshfeld, and AIM Studies. Crystals 2023, 13(9), 1375
  270. A. Barakat, S. Alshahrani, A. M. Al-Majid, A. S.Alamary, M. Haukka, M. M. Abu-Serie, L. R. Domingo, S. Ashraf, Z.-Ul Haq, M. S. Nafieand M. Teleb. New spiro-indeno[1,2-b]quinoxalines clubbed with benzimidazole scaffold as CDK2 inhibitors for halting Non-small cell lung cancer; Stereoselective synthesis, molecular dynamics and structural insights. Journal of Enzyme Inhibition and Medicinal Chemistry, 2023, 38(1):2281260.
  271. A. Barakat, S. Alshahrani, A. M. Al-Majid,
    A. S.Alamary, M. Ali, Mar Ríos-Gutiérrez.  Stereoselective Synthesis of a Novel Series of Dispiro-oxindolopyrrolizidines Embodying Thiazolo[3,2-a]benzimidazole Motif: an MEDT Study of the Mechanism of the [3+2] Cycloaddition Reaction. Chemistry, 2023, 5(4), 2392-2405.
  272. A A.M. Sarhan, M Haukka, A. Barakat, S. M.
    Soliman, A. T. A. Boraei, M. Sopaih, E.E. Salama. 4-Methyl/phenyl-1,2,5,6- tetraazafluoranthen-3(2H)ones Synthesis: Mechanistic Pathway Study and Single Crystal X-ray Analysis of the Intermediates. Crystals, 2023, 13(11), 1537.
  273. E. E. Salama, M. F. Youssef, A. T. A. Boraei, M.S.
    Nafie, M. Haukka, A. Barakat, A. A. M. Sarhan. Discovery of Potent Indolyl-hydrazone as Kinase Inhibitors for Breast
    Cancer: Synthesis, X-Ray Single Crystal Analysis, in vitro and in vivo
    Anti-Cancer Activity Evaluation.     Pharmaceuticals, 2023, 16(12), 1724.
  274. M. S. Altowyan, E. M. Fathalla, J. H. Albering, M.
    A. M. Abu-Youssef, T. S. Kassem, A. Barakat, M. Haukka, A. M.A.
    Badr, S.M. Soliman. Synthesis, X-ray Structures and Hirshfeld analysis of Two Novel Thiocyanate-Bridged Ag(I) Coordination Polymers.     Inorganics 2023, 11(10), 417.
  275. M.S. Islam, A. M. Al-Majid, F. F. El-Senduny,F. A. Badria,Z. Parveen,N. Ravaiz,A. Wadood,A. Ajmal,S.Yousuf,G. Murtaza, S. Ramadan, Hayam M.A.Ashour,  and A. Barakat. Pharmacokinetics, ADME of Spirooxindole–pyrrolidines Embedded with Pyrazole Heterocycle as alpha amylase inhibitor and potential cytotoxic compounds. Journal of Biological Regulators and Homeostatic Agents, 2024, 38, (2): 935-956.
  276. M. S. Nafie, A. M. Al-Majid, M. Ali, A. A. Alayyaf, M. Haukka, S.Ashraf, Z.Ul-Haq, A. El-Faham, and A.Barakat. Exploring Pyrrolidinyl-Spirooxindole Natural Products as Promising Platforms for the Synthesis of Novel Spirooxindoles as CDK2 Inhibitors for Halting Breast Cancer Cells. Front. Chem. - Medicinal and Pharmaceutical Chemistry, 2024, 12:1364378.
  277. A. Barakat, S. Alshahrani, A.M. Al-Majid, A. Alamary, M. Haukka, M. Abu-Serie, A. Dömling, L. R. Domingo, Y. Elshaier, Activation of p53 Signaling and Regression of Breast and Prostate Carcinoma Cells by Spirooxindole-Benzimidazole Small Molecules. Frontier in Pharmacology, 2024, 11:1358089.
  278. T. Q. Alshargabi, S.M. Soliman, A. Zakaria, D. Osman, M. Hagar, F.T. AlShorifi, M. Marie, A. Barakat, M. Haukka, M. Altowyan, M.A. El Sawy, Synthesis, X-ray structure, Hirshfeld, cytotoxicity and anticancer studies of pyrazole and pyridazin-4(H)-one derivatives. Journal of Molecular Structure, 2024, 1304, 137654
  279. H.H. Hammud, N. Sheikh, I. Shawish, H. Bukhamsin, D. Al-Hudairi, A. Wee, M. H. S.Abdul Hamid, S.Maache, H. Al-Rasheed, A. Barakat, A. El-Faham. Bis-(dimethylpyrazolyl)-aniline-s-triazine Derivatives as Efficient Corrosion Inhibitors for C-Steel and Computational Studies. Royal Society Open Science, 2024, 11:231229.
  280. M. M. Abu-Serie, Satoru Osuka, L.Heikal, M. Teleb, A. Barakat, V. Dudeja. Diethyldithiocarbamate-ferrous oxide nanoparticles inhibit human and mouse glioblastoma stemness: Aldehyde dehydrogenase 1A1 suppression and ferroptosis induction. Front. Pharmacol. Sec. Pharmacology of Anti-Cancer Drugs. 2024, 15: 1363511.
  281. A. H. E. Moustafa, H. H. Abdel-Rahman, A. Barakat, H. A. Mohamed, A. S. El-Kholany. An Exploratory Experimental Analysis Backed by Quantum Mechanical Modeling, Spectroscopic, and Surface Study for C-Steel Surface in the Presence of Hydrazone-Based Schiff Bases to Fix Corrosion Defects in Acidic Media. ACS Omega 2024, 9, 14, 16469–16485.
  282. M. N. Abd Al Moaty, Y. El Kilany, L. F. Awad, S. M.
    Soliman,     A. Barakat, N. A. Ibrahim, M. M. Abu-Serie, M. Haukka,
    A.El-Yazbi, M. Teleb. Triggering Breast Cancer Apoptosis via Cyclin-Dependent Kinase Inhibition and DNA Damage by Novel Pyrimidinone and 1,2,4-Triazolo[4,3-a]pyrimidinone Derivatives. ACS Omega     2024, 9, 19, 21042–21057.
  283. Y. M. A. Aziz, M. S. Nafie, P. A. Hanna, S. Ramadan, A. Barakat, M. Elewa Synthesis, Docking, and DFT Studies of Novel Schiff Base Sulphonamide Analogues as Selective COX-1 Inhibitors with Anti-platelet Aggregation Activity. Pharmaceuticals, 2024, 17(6), 710.
  284. M. Hassan, A. El-Faham, A. Barakat, M. Haukka, R. Tatikonda, M.A.M. Abu-Youssef, S.M. Soliman, A. Yousri, Synthesis, X-ray Structure, Cytotoxic, and Anti-Microbial Activities of Zn(II) Complexes with a Hydrazono s-Triazine Bearing Pyridyl Arm. Inorganics 2024, 12, 176.
  285. M. S. Islam, R. M. Al-Jassas, A. M. Al-Majid, M.Haukka, M. S. Nafie, M. M. Abu-Serie,M. Teleb, A. El-Yazbi, A.M. A. Alayyaf, A. Barakat,and M. M. Shaaban. Exploiting spirooxindoles for dual DNA targeting/CDK2 inhibition and simultaneous mitigation of oxidative stress towards selective NSCLC inhibition; Synthesis, evaluation, and molecular modelling studies.
    RSC Medicinal Chemistry    , 2024, 15, 2937-2958.
  286. A. T. A. Boraei, S.M. Soliman, M. Haukka, A. Barakat, A. A. M. Sarhan. β-Enaminones and organic salts from 3-benzoyl-4-hydroxy-6-phenyl-2H-pyran-2-one: Synthesis, X-ray crystal structural studies and antimicrobial activity. Journal of Molecular structure 2025, 1319, Part 1, 139549.
  287. H. H. Hammud, W. A. S. Aljamhi, I. Shawish, N. H. B. Z. Arfan, Malai, Haniti S. A. Hamid, N. S. Sheikh, H. M. Abd El-Lateef, A. Barakat and A. El-Faham. Experimental and Computational Anti-corrosion Behaviors of Pyrazole s-triazine/anilino-morpholino Derivatives for steel in acidic solutions. ACS Omega 2024, 9, 31714−31731.
  288. A. Yousri, S. I. Gad, M. A.M. Abu -Yousse, A. El -Faham, A. Barakat, R. Tatikond, M. Haukka, S. M. Soliman. Synthesis of Co(II) , Mn(II) , and Ni(II) complexes with 4 -(4,6 -bis(3,5 -dimethyl - 1H -pyrazo l - 1 -yl ) -1,3,5 -triazin - 2 -yl)morpholine; X-ray structure, Hirshfeld, AIM, and biological studies. Inorganica Chimica Acta. 2024, 573,122320.
  289. M. S. Altowyan, S. M. Soliman, M. A.M. Abu-Youssef, J. H. Albering, A. Barakat, A. Yousri. New 1D Cd(II) coordination polymer based on L‒arginine ligand; Synthesis, X- ray structure, Hirshfeld analysis, DFT studies, and biological activity. Journal of Molecular Structure 2024, 1318, 139226.
  290. A. Yousri, M. Hassan, A.El-Faham, A. Barakat, M.Haukka, R. Tatikonda, M. A. M. Abu-Youssef; S. M. Soliman. Homoleptic Co(II) and Ni(II) complexes with promising anticancer and antimicrobial activities; Synthesis, X-ray structure, and DFT studies. Journal of Molecular structure 2025, 1321,139774.
  291. S. I. Gad, M. S. Altowyan, M. A. M. Abu-Youssef, A. El-Faham, A. Barakat, R. Tatikonda, M. Haukka, S. M. Soliman, A. Yousri. Synthesis, structural investigations, and potential antimicrobial and anti-cancer activity of mononuclear Zn(II) and Cd(II) complexes decorated by morpholine/pyrazole s-triazine ligand. Applied Organometllaic Chemistry 2024, 1-18.
  292. M.S. Altowyan, A.El-Faham, M. Hassan, A. Barakat, M. Haukka, M.A.M. Abu-Youssef, S.M. Soliman, A. Yousri, Structural and Biological Comparative Studies on M(II)-Complexes (M = Co, Mn, Cu, Ni, Zn) of Hydrazone-s-Triazine Ligand Bearing Pyridyl Arm. Inorganics 2024, 12, 268.
  293. S.M. Khattab, M.S. Altowyan, A. El-Faham, A. Barakat, M. Haukka, M.A.M. Abu-Youssef, S.M. Soliman, A New Bromo-Mn(II) Complex with 1,3,5-Triazine Derivative: Synthesis, Crystal Structure, DFT and Biological Studies. Inorganics 2024, 12, 284.
  294. M. Elewa, M. Shehda, P. A. Hanna, M. M. Said, S. Ramadan, A. Barakat, Y.M. Abdel Aziz. Development of a Selective COX-2 Inhibitor: From Synthesis to Enhanced Efficacy via Nano-Formulation. RSC Adv., 2024,14, 32721-32732.
  295. I. Shawish, S. Al Ayoubi, A.El-Faham, A. Aldalbahi, F. F. El-Senduny, F.A. Badria, Mar Ríos-Gutiérrez, H. H. Hammud, S. Ashraf, Z. Ul-Haq and A. Barakat. Novel spirooxindole-triazole derivatives: unveiling [3+2] cycloaddition reactivity through molecular electron density theory and investigating their potential cytotoxicity against HepG2 and MDA-MB-231 cell lines. Front. Chem. 2024, 12,1460384.
  296. M. M. Abu-Serie, A. Barakat, S. Ramadan, N. H. Habashy. Superior cuproptotic efficacy of diethyldithiocarbamate-Cu4O3 nanoparticles over diethyldithiocarbamate-Cu2O nanoparticles in metastatic hepatocellular carcinoma. Front. Pharmacol. 2024, 15,1388038.
  297. A. T. A. Boraei, S.M. Soliman, M. Haukka, A. Barakat, A. A. M. Sarhan. Efficient Synthesis and Comprehensive Characterization of Bis-pyrazole Derivatives: Including X-ray Crystallography and Hirshfeld Surface Analysis. Journal of Heterocyclic Chemistry. 2024, 1–12.
  298. A. A. Alayyaf, M. Ali, M. A. Alwehaibi, M.K. Al-Muhanna, S. M. Soliman, Mar Ríos-Gutiérrez, M. Haukka, and A. Barakat, Utilizing MEDT Analysis of [3+2] Cycloaddition Reaction: X-ray Crystallography of Spirooxindole Linked with Thiophene/Furan Heterocycles and Triazole Framework. BMC Chemistry, 2024, 18:229
  299. M. K. Al-Muhanna, A. Barakat,M. S. Islam, A.M. Al-Majid, M. Ali, K. Zia, Zaheer Ul-Haq, A. Dömling,F.F. El-Sendunyand F. A. Badria, Novel Spirooxindole-Benzofuran Scaffold: Potential Inhibition Against Hepatocellular Carcinoma by Targeting MDM2-p53 Interaction. ChemistrySelect 2024, 9, e202403953 (1 of 13).
  300. Me. S. Altowyan, S. M. Soliman, M. A. M. Abu-Youssef, M. Haukka, A. Barakat, A. Yousri. A new Ag(I) complex based on asymmetric azine-type ligand as a promising anticancer agent: Synthesis, X-ray structure, and DFT calculations. Journal of Molecular Structure 2025, 1324, 140908.
  301. W. A. Abdelhalim, A. R. Rabee, S. M. Soliman, M. Hagar, E. A. Moneer, B. A. Bakr, A. Barakat, M. Haukka, Hanaa A. Rasheed. New formyl indole derivatives based on thiobarbituric acid and their nano-formulations; synthesis, characterization, parasitology and histopathology investigations. Scientific Reports 2024, 15, 299.
  302. H. H. Al-Rasheed, S. A. Al-Khamis, A.Barakat, A. A. Masoud, A. A. Sobhy, D. A. Ghareeb, B. G. de la Torre, F. Albericio,A. El-Faham. Design and Synthesis of s-Triazine-isatin hybrids with Potent Anticancer Activity, Targeting A549 Lung Adenocarcinoma via EGF Inhibition. Tetrahedron, 2025, 171, 134424.
  303. M.S. Nafie, M. Ali, M. A.Alwehaibi , A.A. Alayyaf, M. K. Al-Muhanna, N. Almuqati,  A. A. Alghamdi,  M. Haukka , S. S. Tariq, Zaheer-Ul Haq and A. Barakat. Potent EGFR/PARP-1 Inhibition by Spirooxindole-Triazole Hybrids for Targeted Liver Cancer Therapy. RSC advances 2025, 15, 58-74.
  304. H. H. Al-Rasheed; S. J. Zamisa; I. Shawish; A. Barakat; A. El-Faham; B. G. de la Torre; F. Albericio. The effect of molecular conformation of s-triazine derivatives on their photophysical properties. Results in Chemistry, 2025, 13, 101966.
  305. A. Barakat, F. F. El-Senduny,  M. S. Islam, A. M. Al-Majid,  Y. A. M. M. Elshaier, E.A.Mazyed, and F.A. Badria. Nanoformulation of Spirooxindole and Methods for Treating Hepatocellular Carcinoma. Pharmaceutics   2025, 17, 93.
  306. A. T. A. Boraei, M. S. Nafie, A. Barakat, T. Tanaka, K. Kawano, T. Tojo, S. Aoki, A. A. M. Sarhan. Synthesis of new functionalized bioactive S-substituted indolyl-triazoles as cytotoxic and apoptotic agents through multitargeted kinase inhibition. Bioorganic Chemistry. 2025, 156, 108154.
  307. M. M. Abu-Serie, Ana K. Gutiérrez-García, M. Enman, U. Vaish, H. Fatima, A. Barakat, V. Dudeja. Ferroptosis- and stemness inhibition-mediated therapeutic potency of ferrous oxide nanoparticles-diethyldithiocarbamate using co-spheroid 3D model of pancreatic cancer. Journal of Gastroenterology 2025, Under review.
  308. M. S. Islam, A. Barakat , A. M.A. Alayyaf, M. Haukka, V. P. Verma, M. M. Abu-Serie, A.F. El-Yazbi, M. G. Shehat, M. Alseqely, M. Teleb. Synthesis and evaluation of marine-inspired spirooxindoles as multifaced DNA damaging agents for combating non-small cell lung cancer and possible associated bacterial infection. ACS Medicinal Chemistry Letters 2025, Under review.
  309. R. M. Al-Jassas; M. S. Islam; A. M. Al-Majid; M. Haukka; M. S. Nafie; M. M. Abu-Serie; M. M. Shaaban; A. M. A. Alayyaf; L. R. Domingo; R. Khalil; Z. Ul-Haq; A. Barakat. Marine-inspired spirooxindole PIM-1 kinase inhibitors endowed with concomitant TRKA/CDK2 inhibition for multifaceted NSCLC apoptotic induction. Asian Journal of Organic Chemistry. 2025, Under review.
  310. E. M. Hassan, A. Rabee, S. M. Soliman, M. Hagar, E.A. Moneer, S. Ramadan, A.  Barakat, H. Abdel-Hamid, A. Zakaria, H. A. Rasheed, Nano-formulations for hydrazones; synthesis, characterization, parasitology and histopathology investigations. ACS Omega, 2025, Under review.
  311. A.A. M. Sarhana, M. Haukka, S. M. Soliman, A. Barakat, A. T. A. Boraeie. Catalyst Free Regiospecific Amination, Structural Elucidation, and Potential Utilization of Pyran-2,4-dione derivatives as Novel Antimicrobial Agents. Tetrahedron  2025, Under review.
  312. Eman A. Bakr, Morsy A. M. Abu-Youssef, Ayman El-Faham, Assem Barakat, Matti Hauka, Saied M. Soliman, Amal Yousri. Mn(II), Co(II), and Ni(II)-isothiocyanato Complexes with Promising Cytotoxic and Antimicrobial Properties; Synthesis, X-ray Structure, and Theoretical Studies. Journal of Molecular Structure 2025, Under review.
  313. Mostafa A. El-Naggar, Morsy A. M. Abu-Youssef; Matti Haukka, University of Jyväskylä; Assem Barakat; Ayman El-Faham; Saied M. Soliman; Amal Yousri. Water soluble silver coordination polymers constructed from bridging pyrazine ligands: syntheses, X-ray structures, anticancer and antimicrobial investigations. Inorganic Chemistry 2025, Under review.
  314. S.M. Khattab, A. El-Faham, A.Barakat, R. C. Fischer, M. A. M. Abu-Youssef, S. M. Soliman and A.Yousri. Self-assembled d10-Metal (Cd(II), Zn(II), and Ag(I)) Complexes of Amino bis-Pyrazolo-s-Triazine Pincer Ligand with Promising Anticancer and Antimicrobial Activities. Applied Organometallic Chemistry. 2025, Under review.
  315. Y. A. M. M. Elshaier, A. Kandeil, A.N. El Taweel, M. A. Abou-Salim, A.S. Eltaweil, M. Darewish, K.A. M Abouzid, S. A.Khan, Z.Ul-Haq, M.F.El-Behairy, A.Barakat. Integrated Multistep Virtual Screening, In vitro Evaluation and Nanoformulation to Identify Chemical Probe Based Fluorinated Drugs Against SARS-CoV-2. Heliyon, 2025, Revision.
  316. M.S.Islam, S.M. Soliman, M. Haukka, and A.Barakat. X-ray Single Crystal Structure Combined with Hirshfeld Analysis, and Density Functional Theory (DFT) Studies for Two Friedel-Crafts Adducts Based on Indole and Benzofuran Scaffolds. Crystals, 2025, Under review.
  317. Eman A. Bakr, Morsy A. M. Abu-Youssef, Ayman El-Faham, Assem Barakat, Matti Hauka, Saied M. Soliman, Amal Yousri. Synthesis, X-ray Structure, and Theoretical Studies of Mn(II) and
    Co(II)-isothiocyanato Complexes with Promising Cytotoxic and Antimicrobial Properties. Inorganics, 2025, Under review. Revised.
  318. M. Ali; A. Barakat; M. M. Ayad; N. A. Salahuddin. Aniline-anthranilic acid copolymer-chitosan/montmorillonite/silver@silver chloride nanohybrid as a carrier for (E)-N'-(pyridin-2-ylmethylene) hydrazinecarbothiohydrazide Antimicrobial activity and Release studies. InOrganic, 2025, Under review.

 

Chapter BooK

  • Ihab Shawish, Abdullah Mohammed Al-Majid, and Assem Barakat. Chapter 16. Spirooxindole derivatives as an anti-cancer agent, Page: 411-438.  Book title: Spirooxindole: Chemistry, Synthesis, Characterization and Biological Significance; Elsevier, 2024. DOI: https://doi.org/10.1016/B978-0-443-22324-2.00016-3

 

Patents

  1. A. Barakat, M. Ali, A. M. Al-Majid, S. Yousuf, M. Iqbal Choudhary. "Diethyl Ammonium Salts of Phenyl-Substituted Thiobarbituric Acid as Anti-Diabetic Agents ". US9527820B1- Dec., 27, 2016.
  2. Abdullah Mohammed Al-Majid, Mohammad Shahidul Islam, A. Barakat, Sammer Yousuf and, M. Iqbal Choudhary. "Alpha-Glucosidase Inhabitors". US20170088516A1. Oct., 31, 2017
  3. A. Barakat, M. S. Islam, A. M. Al Majid, H.M. Ghawas, F.F. El-Senduny, F. A. Badria, Y. A.M. M.Elshaier, H. A. Ghabbour. Substituted spirooxindoles.  US9822128B1; Nov., 21, 2017.
  4. Hassan Hasan Hammud, Waleed Abdullah Saeed Aljamhi, Ayman Sadek Ahmed El-Faham, Assem Barakat, Ihab Shawish, Nadeem Sadiq Sheikh, Khurshid Ayub. Spirooxindole-Copper complex as novel efficient anticorrosion agent for C-steel. US11840545B1. Dec, 12, 2023.
  5. A. Barakat, F.F. El-Senduny, M. S. Islam, A. M. Al Majid, Y. A.M. M.Elshaier, Eman Ahmed Ibrahim Mazyed, F. A. Badria, NANOFORMULATION OF SPIROOXINDOLE AND METHODS FOR TREATING HEPATOCELLULAR CARCINOMA. US11944604B1. April 2, 2024.

 

SUPERVISION THESIS:

PI-Supervisor:

#

Name

Degree

Year

THESIS TITLE

1

Fesal M. El-Khtany

M.Sc

2012

Synthesis of some oxazole and imidazole derivatives and the study their chemical reactions and their pharmacological effectiveness and toxicity.

2

Hany G. S. El-Najar

M.Sc

2013

Preparation of new organic compounds using Aldol-Michael reaction

3

Bandr M.S. El-Khtany

M.Sc

2014

Synthesis and Biological Evaluation of Novel Pyrazolone Derivatives

4

Hessain M. Ghawas

M.Sc

2015

Synthesis of Novel Class of Spiro Heterocycles via Dipolar Cycloaddition Reactions

5

M. Ali

PhD

(Co-PI)

2014

Synthesis and Characterization of Azine and Azole Derivatives Supported on Delivery Systems Based on Polymer- Clay Nanocomposites.

6

Saleh Atef

M.Sc

2016

Regioselective Asymmetric Michael Addition Reaction Catalyzed by Soft Lewis Acid.    

 

7

Abdullah Alamary

Ph.D

(Co-PI)

2018

Design and synthesis of some novel bidentate chiral ligands and their applications in asymmetric catalysis.

8

Saeed Alshahrani

Ph.D

2018

Synthesis of Novel Classes of Spiro-Benzimidazole as Potential Anti-Cancer Agents.

9

Tagreed ElOtaibi

M.Sc

2019

Synthesis of Some Novel Nitrogen and / or Oxygen Containing Heterocyclic Compounds with Evaluation of their Biological Activities.

10

Ihab Shawish

Ph.D

2019

Synthesis and Characterization of Novel Series of Heterocyclic and Macrocyclic Based on Triazine Moiety

11

Refaah M. El-Jassas

M.Sc

(Co-PI)

2022

Synthesis, Characterization, and Biological Evaluation of Some Spiro Compounds Containing Pyrazole Moiety.

12

Norah Elkahtani

M.Sc

(Co-PI)

2022

Synthesis Characterization and Biological Evaluation of series of trisubstituted s triazine

13

Moayad Abdullah Alwehaibi  

 

M.Sc

2022

Asymmetric Formal [3+2]-Cycloaddition Reactions as a Versatile Platform to Acquire Biologically Important Active Compounds

14

Sarah Abdullah ElSebaiy

M.Sc

2023

Development of New Small Molecules as Human Carbonic Anhydrase Inhibitor for Cancer Therapy

15

Reem Saad Elmatiery

M.Sc

2024

Synthesis of New Fluorinated Spiro- Compounds for Pharmaceutical Applications

16

Nouran Fahad ElAid

M.Sc

2024

Synthesis and Applications of S Triazine Incorporating Triazole Motif Exploring Novel Strategies for Chemical Design

17

Dalia Elshamemiry

M.Sc

(Co-PI)

2023

Synthesis, Molecular Modeling and Biological Evaluation of Novel Thienopyrimidine and Thienoquinazoline derivatives targeting Type-II Diabetes Mellitus

 

Conferences/Seminars/ Symposia/ Workshops/Webinars attended

  • Virtual participation in Chemistry world webinar; Copper-catalysed carbon-heteroatom bond-forming processes. Oct 15, 2024.
  • “COMSTECH-NAPRECA; Webinar on Recent Advances in Nuclear Magnetic Resonance Spectroscopy” Jointly organized by COMSTECH and NAPRECA on 20th February, 2023
  • Speaker at ICES2023, held in Riyadh, Saudi Arabia on Februaray 6-8, 2023.
  • Oral presentation for the   Saudi Chemical Society Webinars series: The Chemistry of Spirooxindole Scaffold: Synthesis and Applications Towards Cancer Treatment. Feb., 6, 2022.
  • Oral presentation for the   2021 International Chemical Congress of Pacific Basin Societies virtually, December 16-21, 2021. Pacifichem 2021.
  • Plenary speaker presentation at the 3rd International Webinar on Chemistry and Pharmaceutical Chemistry, October 29, 2021.
  • Virtual participation in COMSTECH-NTD network joint lecture series “The role of amino acids in the bioenergetics of Trypanosoma cruzi” delivered by Dr. Ariel Silber, Organized by COMSTECH. Dec 22nd, 2021.
  • Virtual participation in COMSTECH Webinar on “Advanced Methods for Structure Determination of Proteins and their complexes: Drug discovery for motor neuron disease to COVID-19" Delivered By Prof. Dr. Samar Hasnain, Organized by COMSTECH. September 9, 2021.
  • virtual participation in NTD-COMSTECH lecture series. Protozoan ‘Drug’ Discovery: Old Drugs, New Targets And Mining For Novelty. Delivered by Prof. Dr. Paul W. Denny. Organized by COMSTECH. August 6th, 2021.
  • Virtual participation in the COMSTECH Webinar on Cyclic Peptides For Anticancer Drug Delivery By Prof. Dr. Keykavous Parang Organized by COMSTECH. July 13, 2021
  •   Virtual participation in the NTD - COMSTECH lecture Series Lecture No. 1; CRISPR-cas9 Genome Editing of Leishmania and Drug Target Validation" delivered by Prof. Dr. Jeremy Mottram held on 25th June 2021.
  • Virtual participation “ Artificial Molecular Machines: Going from Solution to Surfaces" Fri, Jun 25, 2021 2:00 PM Presented by Nobel Laureate Sir Fraser Stoddart , organized by ACS webinars series.
  • Virtual participation in COMSTECH webinar Structure-based design & development of inhibitors of the Tankyrases, drug targets in cancer and diabetes Delivered by Prof. Dr. Michael David Threadgill.  Organized by COMSTECH. 8 th June 2021.
  • Virtual participation in RSC Desktop Seminar Lectureship Series with Natural Product Reports. Mon, Mar 15, 2021.
  • Harvesting Water from Desert Air; Presented by Prof. Omar Yaghi, Organized by AMRC and Saudi Chemical Society webinar; 21/7/2020.
  • Virtual Meeting, Molecular Structure - Techniques to Resolve, MSTR-2020, 25/6/2020.
  • International Webinar on Chemistry and Biology, India, 29-30/6/2020.
  • KFUPM Forum (1): Thriving in the Age of Corona: Challenges and Opportunities". Tue, Apr 21, 2020.
  • COVID-19: A Groundwork for Therapeutic Agents and Vaccines, ACS webinars, Wed, Apr 15, 2020.
  • 7th International Chemistry Conference, Riyadh, Saudi Arabia, November 12-14, 2018.
  • Active learning and Interactivity; presented by Dr. Kevin Yee (University of South Florida); King Saud University, Riyadh, Saudi Arabia, September 5, 2018.
  • Course Design, Assessment and Delivery; presented by Dr. Kevin Yee (University of South Florida); King Saud University, Riyadh, Saudi Arabia, September 4, 2018.
  • Lessons from Cognitive Science; Presented by Dr. Kevin Yee (University of South Florida); King Saud University, Riyadh, Saudi Arabia, September 3, 2018.
  • 255th ACS National Meeting, New Orleans, LA, March 18-22, 2018.
  • Work Stress Management, King Saud University, Riyadh, Saudi Arabia, January 10, 2018.
  • Podcast and Educational Mobile, King Saud University, Riyadh, Saudi Arabia, December 28, 2017.
  • Course Specification and Report, King Saud University, Riyadh, Saudi Arabia, December 24-25, 2017.
  • Using Modern Instruction Strategies, King Saud University, Riyadh, Saudi Arabia, December 14, 2017.
  • Effective College Teaching, King Saud University, Riyadh, Saudi Arabia, December 12-13, 2017.
  • Methods of Learning Outcomes Assessment, King Saud University, Riyadh, Saudi Arabia, November 08, 2017.
  • 14th EURASIA Conference on Chemical Sciences (EuAsC2S-14) held in Karachi, Pakistan, December 15 - 18, 2016.
  • 6th International Chemistry Conference, Riyadh, Saudi Arabia, November 8-10, 2016.
  • 14th International Conference on the Chemistry of Antibiotics and other Bioactive Compounds (ICCA 2015), to be held in Galveston Island, Texas from October 13-16, 2015.
  • 18th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis (OMCOS18) held in Sitges (Barcelona, Spain) from June 28th to July 2nd 2015 at the hotel Melià Sitges. 
  • Symposium of Materials and Energy for New Energy Technologies (organized by Royal Society of Chemistry and Saudi Chemical Society) 9th Dec 2013, KSU, Riyadh, KSA.
  • The 15th Asian Chemical Congress, Resorts World Sentosa, Singapore, Aug 19-23, 2013.
  • 1st X-Ray Crystallography Workshop Presented By. Prof. Dr. Hoong-Kun Fun Department of Pharmaceutical Chemistry College of Pharmacy, Riyadh, KSA, 23rd to 27th February 2013.
  • ISCHIA ADVANCED SCHOOL OF ORGANIC CHEMISTRY, Ischia Island (Napoli) Italy, September 22 - 26, 2012
  • International Conference of Young Chemists (ICYC), to be held in Amman- Jordan on April 8 - 10, 2012.
  • Specialized Training Courses “NUCLEAR MAGNITIC RESONANCE “Presented By. Prof. Dr. M. IQBAL CHOUDHARY, Saudi Chemical Society, Chemistry Department, – KSU. 19-21, November 2011 in Riyadh.
  • The Fourth International Chemistry Conference “Chemistry and its Role and Application in Development” 19-21, November 2011 in Riyadh – KSU.
  • Essentials of research project management. King Saud University, Riyadh, May, 2011.
  • The art of good research and how to make it happen. King Saud University, Riyadh, March, 2011.
  • International symposium metal–catalyzed syntheses new ways forward for industrial processes). Accademia nationale dei lincei, fondazione “guido donegani” Roma, Italy, May, 2007.
  • Organic chemistry “Target synthesis: challenges, strategies and methods” séminairehors-ville du 3éme cycle en chimie 2007 (CUSO-2007). Villars, Switzerland, Sept, 2007.

Peer Review Assistance

@Accreditation

  • Independent peer reviewer for the SSR, Chemistry Program, form the Prince Sattam Bin Abdulaziz University, in Al-Kharj, Saudi Arabia, 2023.

@Journal

  1. Green Chemistry.
  2. Biomacromolecules, ACS.
  3. Organic Letters.
  4. ACS Sustainable Chemistry & Engineering.
  5. Energy & Fuels.
  6. European Journal of Medicinal Chemistry.
  7. Sensors & Actuators: B. Chemical
  8. Bioorganic and medicinal chemistry.
  9. Biomedicine & Pharmacotherapy.
  10. Bioorganic Chemistry.
  11. Ultrasonics – Sonochemistry.
  12. New Journal of Chemistry.
  13. Arabian Journal of Chemistry.
  14. Journal of Molecular Structure.
  15. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
  16. Polyhedron.
  17. Polycyclic Aromatic Compounds.
  18. Research on Chemical Intermediates.
  19. Journal of Saudi Chemical Society.
  20. Polymers for Advanced Technologies.
  21. Molecules.
  22. Archiv der Pharmazie.
  23. Chemical Biology & Drug Design.
  24. Phosphorus, Sulfur, and Silicon and the Related Elements.
  25. Heterocyclic Communications.
  26. Polycyclic Aromatic Compounds.

 

@Thesis

  • Peer Reviewer for the master thesis presented by Munirah S. Al-Har under title of “Reaction of isatoic anhydride and its halo- derivatives with different Amines” in 10/2012, Hail University, Hail, Saudi Arabia.
  • Peer Reviewer for the master thesis presented by Nahed Ahmed Kaal under title of “Synthesis of novel heterocyclic compounds containing sulphur” in 2014, King Saud University, Riyadh, Saudi Arabia.
  • Peer Reviewer for the master thesis presented by Nada ALJEID under title of “Synthesis of some heterocyclic compounds derived from cycloalkyl[b] thiophene and evaluation of their biological activities” in 12/2016, King Saud University, Riyadh, Saudi Arabia.
  • Peer Reviewer for the master thesis presented by Mohamed Wahby under the of “Synthesis and application of environmental friendly amphiphilic smart nano-capsules as self-healing protective coatings of metal substrates” in 28/2/2018, King Saud University, Riyadh, Saudi Arabia.
  • Peer Reviewer for the master thesis presented by Nuha Mari Maseer Alanazi under the of “Synthesis and Reactions of Some New Heterocyclic Compounds Bearing Pyridine Moiety with Potential Biological Activity” in 15/2/2022,  Jouf University, Sakakah, ‎Al Jawf‎, ‎Saudi Arabia.
  • Peer Reviewer for the master thesis presented by Norah Mohammed A. Al-Taysan under the of “DESIGN SYNTHESIS AND ELECTROCHEMICAL CHARACTERIZATION OF NOVEL PORPHYRIN MACROMOLECULES” in 15/2/2023, King Faisal University‎, ‎ Hofuf,  Saudi Arabia.

 

@ International external examiner-Thesis

 

  • External examiner for a Master of Medical Science in Pharmaceutical Chemistry; title “Thiobarbituric acid a useful scaffold for medicinal chemistry” College of Health Sciences, University of Kwazulu-Natal, South Africa, 2018.
  • External examiner for a Doctor Philosophy (PhD) in chemistry title “Structural investigation and molecular interaction studies on some antineoplastic drugs and its complexes” College of Science and Humanities, Anna University, Chennai, India, 2018.

@ International reviewer-project

 

  • Peer Reviewer for The National Science Centre, Poland, 2019.

@ National reviewer-project

 

  • Peer Reviewer for Research Proposal Review Form for the Sustainability Program, University of Jeddah – Deanship of Scientific Research Saudi Arabia, 2023.

@ Faculty promotion

 

  • Peer Reviewer for the academic staff candidate form the Arab American University, Jenin, Palestinian, 2017.
  • Peer Reviewer for the academic staff candidate form the Taibah University, in Medina, Saudi Arabia, 2019.
  • Peer Reviewer for the academic staff candidate form the Tabuk University, in Tabuk, Saudi Arabia, 2022.
  • Peer Reviewer for the academic staff candidate form the University of Jeddah, in Jeddah, Saudi Arabia, 2022.
  • Peer Reviewer for the academic staff candidate form the Taif University, in Taif, Saudi Arabia, 2022.
  • Peer Reviewer for the academic staff candidate form the Prince Sattam Bin Abdulaziz University, in Al-Kharj, Saudi Arabia, 2022.
  • Peer Reviewer for the academic staff candidate form the Taibah University, in Medina, Saudi Arabia, 2022.
  • Peer Reviewer for the academic staff candidate form the University of Jeddah, in Jeddah, Saudi Arabia, 2023.
  • Peer Reviewer for the academic staff candidate form the King Faisal University, Saudi Arabia, 2023.
  • Peer Reviewer for the academic staff candidate form the Umm Al-Qura University, Saudi Arabia, 2023.
  • Peer Reviewer for the academic staff candidate form the Al-Hussein Bin Talal University, Jordan, 2023.
  • Peer Reviewer for the academic staff candidate form the King Abdulaziz City for Science and Technology (KACST) in Riyadh, Saudi Arabia, 2023.
  • Peer Reviewer for the academic staff candidate form the University of Hail, Hail, Saudi Arabia 2024.
  • Peer Reviewer for the academic staff candidate form the University of Jeddah, in Jeddah, Saudi Arabia, 2024.

 

 

Guest Associate Editor

https://www.mdpi.com/journal/crystals/special_issues/King_Saud_University

https://www.mdpi.com/journal/crystals/special_issues/Crystals_Saudi_Arabia

https://www.mdpi.com/journal/molecules/special_issues/Metal_Based_Complex_Medicinal

 

 

Languages

    1. Arabic: Native language.                                                               
    2. English: Very good (writing and speaking).  
    3. Italian: Good.

Personal Information

Birth Date

4/2/1981

Place of birth

Egypt

Nationality

Egyptian

Status

Married [2 Childs: Eyad and Ellen (US citizen)]

Researcher ID

 

Web of Science ID: E-2071-2013

Scopus ID: 55773267300

ORCID 0000-0002-7885-3201

http://www.researcherid.com/rid/E-2071-2013

Websites

http://fac.ksu.edu.sa/ambarakat

https://www.researchgate.net/profile/Assem_Barakat

https://scholar.google.com/citations?user=HF3MerwAAAAJ&hl=en

Passport details

Number: A37035677

Date of Issue:8/3/2024

Validity:7/3/2031

Email

ambarakat@ksu.edu.sa; barakat.assem@yahoo.com

 

Collaborators

    • Prof. Dr. Alexander Dömling, Department of Drug Design, University of Groningen Antonius Deusinglaan 1, 9700 AD Groningen (The Netherlands) E-mail: a.s.s.domling@rug.nl
    • Prof. Dr. Muhammad Iqbal Choudhary, H.I., S.I., T.I.Director International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270 Pakistan. hej@cyber.net.pk; iqbalhej@yahoo.com; iqbal.choudhary@iccs.edu
    • Prof. Dr. Matti Haukka, Department of Chemistry, University of Jyväskylä, P.O. Box 35, FI-40014 Jyväskylä, Finland. matti.o.haukka@jyu.fi
  •               Prof. Dr. Luis R. Domingo, Department of Organic Chemistry, University of Valencia, Dr. Moliner 50, 46100 Burjassot, Valencia, Spain. domingo@utopia.uv.es
    • Professor Fernando Albericio, Department of Organic Chemistry, University of Barcelona, Barcelona Science Park, Baldiri Reixac 10, 08028- Barcelona, Spain, phone: +34 93 403 70 88, celular: +34 618 089 145; email: Albericio@ukzn.ac.za; fernandoalbericio@gmail.com; albericio@ub.edu
    • Prof. Dr. Farid A. Badria, Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura 35516 Egypt. faridbadria@gmail.com

 

ACADEMIC REFEREES:

 Available on request.

    • Prof. Dr. Alexander Dömling, Department of Drug Design, University of Groningen Antonius Deusinglaan 1, 9700 AD Groningen (The Netherlands) E-mail: a.s.s.domling@rug.nl
    • Professor Fernando Albericio, Department of Organic Chemistry, University of Barcelona, Barcelona Science Park, Baldiri Reixac 10, 08028- Barcelona, Spain, phone: +34 93 40370 88, celular: +34 618 089 145; email: Albericio@ukzn.ac.za; fernandoalbericio@gmail.com; albericio@ub.edu
    • Prof.Dr. René Peters, Universität Stuttgart, Institut für Organische Chemie, Pfaffenwaldring 55, 70569 Stuttgart, Germany. rene.peters@oc.uni-stuttgart.de
    • Prof. Ayman El-Faham, Ph. D; D.Sc. Professor Emeritus of Organic and Peptide Chemistry; Department of Chemistry, Faculty of Science, Alexandria University P.O. Box 426, Ibrahimia, 21321 Alexandria, Egypt. ayman.elfaham@alexu.edu.eg
    • Prof. Dr. Luis R. Domingo, Department of Organic Chemistry, University of Valencia, Dr. Moliner 50, 46100 Burjassot, Valencia,Spain. domingo@utopia.uv.es