Methods and compositions for increasing biological molecule stability
Bardwell, James . 2015
The present invention relates to methods and compositions for enhancing
folding and stability of biological molecules. In particular, the present
invention relates to methods and compositions for identifying biological
molecules with enhanced stability. The present invention further relates
to host cells that confer enhanced stability to biological molecules
expressed therein.
Polyphosphate polymers are chains of phosphate monomers chemically
bonded together via phosphoanhydride bonds. They are found in all prokaryotic and
eukaryotic organisms and are among…
Phosphate additions in processed foods are a health risk that has been overlooked. This study examined the
effects of a permitted food additive (E452; Sodium Hexametaphosphate (SHMP)) on…
Protein aggregation is implicated in different human diseases. It also makes the protein less desirable candidate for industry as they exhibit reduced biological activity. Proteins tend to…