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Ajamaluddin Malik

Associate Professor

Associate Professor

كلية العلوم
Building no 5, room no 2A56
السيرة الذاتية

CV

مختصر السيرة الذاتية
Dr. Ajamaluddin Malik graduated at the Institute for Biochemistry & Biotechnology at the Martin Luther University, Germany. After the completion of his Ph.D. (2007), he was a postdoctoral fellow at the Molecular, Cellular & Developmental Biology at the University of Michigan (USA), before joining the King Saud University in 2010. His main areas of research are Protein engineering, recombinant protein production, down-stream processing and biophysical characterization of the proteins.
نص السيرة الذاتية

Dr. Ajamaluddin Malik
Associate Professor
Department of Biochemistry
College of Science
King Saud University
Riyadh,
Saudi Arabia
E-mail: amalik@ksu.edu.sa
 
 
MAJOR ACCOMPLISHMENT
 
• Successfully completed two KACST sponsored project:

  1. Titled “Overexpression and purification of recombinant camel Heat Shock Protein 6”.
  2. Titled “Optimization of expression and purification of Camelus dromedaries glucose transporter 4 (GLUT4) in E.coli and its purification”

• Two NPST sponsored projects are on the verge of completion:

  1. Titled “Elucidation of unfolding-refolding mechanism of wild type and mutants of camel eye lens protein zeta-crystallin”
  2. Titled “Chaperones and Proteases in the quality control of protein misfolding disease”

• NPST approved research grant:

  1. Titled “Development of a protein folding biosensor to study protein misfolding diseases”     

• Identified drug like molecule against MERS-CoV.
• Developed a novel fusion system for the production of therapeutic proteins.
• Developed selection system for protein engineering in the wide range of hosts.
• Developed a novel fluorogenic assay for the quantification of aspartic proteases.
• Thorough experience in protein expression and purification.
• Good skill in protein refolding.
• Chemical mutagenesis and gene mapping of phage T4.
• Synthesis and characterization of peptides.
 
EDUCATION
• Ph.D. Industrial Biotechnology, Martin Luther University, Germany, May 2007
• M.Sc. Biotechnology, Aligarh Muslim University, India, July 1997-June 1999
• B.Sc. (Hons) Chemistry, Aligarh Muslim University, India, July 1993-June 1996
• Completed teaching course on “Science teaching in higher education” from   University of Michigan, USA, 2009
 
 
RESEARCH EXPERIENCE
 
Oct 2018- Present, Associate Professor, Protein Research Chair, King Saud University, Riyadh
 
Nov 2010-Oct 2018, Assistant Professor, Protein Research Chair, King Saud University, Riyadh
• Established laboratory infrastructure for cloning, expression, purification and characterization of recombinant proteins.
• Established state-of-art techniques for biophysical characterization of recombinant proteins.
• Identified potential drug like molecule against MERS-CoV.
• Mentored master students for accomplishment of their research projects.
• Completed two KACST projects, two NPST projects ongoing and one NPST project accepted.
 
July 2007- Aug 2010, HHMI research associate, University of Michigan, USA
• Developed a protein folding biosensor for measuring in vivo protein stability.
 
Mar 2002–May 2007, Ph.D. student, Martin Luther University, Germany
• Established a novel system for the production of therapeutic proteins in native state in the periplasm.
• Developed a novel fluorogenic assay based on EGFP for pepsin estimation.
• Designed a new strategy for one step efficient purification.
• In-vitro refolding of human pepsinogen.
• Expression and purification of recombinant proteins.
 
Jan 2000 – Feb 2002, Research fellow, Aligarh Muslim University, India
• Prepared intron mutants of bacteriophage T4 induced by alkylating agent and screened using white halo plaque phenotype technique.
• Mapping of point mutation in intron by homologous recombination method.
 
July 1998 – April 1999, M.Sc. project, Aligarh Muslim University, India
• Isolation and characterization of MDR-Plasmid from E. coli of sewage water at Aligarh.
 
May – June 1998, Summer research assistant, All India Institute of Medical Sciences, India
• Synthesis, purification and characterization of peptides.
 
 
 
 
ACADEMIC AWARDS & HONORS
 
• HHMI Research Associate, 2007-2010.
• Junior Research Fellowship from University Grant Commission. India, July 2001
• Junior Research Fellowship from Indian Council of Medical Research. India, July 2001
• National Eligibility Test for teaching in higher education. India, Dec 2000
• Studentship from D.B.T (Govt. of India) during July 1997-April 99 for academic excellence.
 
 
PATENTS
 
4. Ajamaluddin Malik- “Methods of development of protease assay” (under preparation).
 
3. Hazem Ahmed Ghabbour, Hatem Abdelkader Abdel Aziz, Ajamaluddin Malik, Mohammad A. Alsenaidy, Hamad M. Alkahtani, Abdulrahman M. Alsenaidy, Wagdy M. Eldehna. xxxxxxxx as papain-like protease (PLpro) inhibitors in Middle East Respiratory Syndrome Coronavirus (MERS-CoV) (Patent filed at Intellectual Property and Technology Licensing, King Saud University on 21.09.2016)
 
2. James Bardwell, Linda Foit, Ajamaluddin Malik, Tobias Baumann, and Maximilian Kern “Methods and compositions for increasing biological molecule stability” (US Patent No.: US8986997 B2)
 
1. Ajamaluddin Malik, Brigitte Söhling & Rainer Rudolph (2005) - “Periplasmic production of proteins with therapeutic value by a fusion to a E.coli ecotin*”-(German Patent-DE102005050732A1; publication date: 26.04.2007)
* Title translated from German to English
 
PUBLICATIONS
 
39. Ajamaluddin Malik, Nayyar Rabbani, Abdulrehman M Alsenaidy, Mohammad A Alsenaidy, In-silico structural modelling, phylogenetic analysis and the evaluation of physiochemical/ structural properties of the eye lens zeta-crystallin protein across different animal species. Manuscript under revision 3Biotech.
38. Nasser Abdulatif Al-Shabib, Javed Khan, Ajamaluddin Malik,
Priyankar Sen, Sriroopreddy Ramireddy, Sudandiradoss Chinnappan, Salman Freeh Alamery, Fohad Mabood Husain, Aqeel Ahmad Allura red rapidly induces amyloid-like fibril formation in hen egg white lysozyme at physiological pH. Submitted in Molecules.
37. Javed Masood Khan. Mukhtar Ahmed, Anwar Ahmed, Ajamaluddin Malik, Priyankar Sen, Salman Freeh Alamery. Different conformational state of hen egg white lysozyme formed in the exposure of sodium dodecyl benzenesulfonate (SDBS) surfactant. Submitted in International Journal of Biological Macromolecules
36. Nasser Abdulatif Al-Shabib*, Javed Masood Khan, Ajamaluddin Malik, Mohammad A Alsenaidy, Md Tabish Rehman, Mohamed F. AlAjmi, Abdulrahman M Alsenaidy, Fohad Mabood Husain, Rizwan Hasan Khan. Molecular insight into binding behavior of polyphenol (rutin) with beta lactoglobulin: Spectroscopic, molecular docking and MD simulation studies. Journal of Molecular Liquids, 1 November 2018, Volume 269Pages 511-520.
35. Ajamaluddin Malik, Javed M. Khan, Salman F. Alamery, Dalia Fouad, Nikolaos E. Labrou, Mohamed S. Daoud, Mohamed O. Abdelkader, Farid S. Ataya.  Monomeric Camelus dromedarius GSTM1 at low pH is structurally more thermostable than its native dimeric form. PlosOne 2018 Oct 10;13(10):e0205274
34. Javed Masood Khan, Mohammad Rizwan Khan, Priyankar Sen, Ajamaluddin Malik, Mohammad Irfan, Rizwan Hasan Khan. An intermittent amyloid phase found in gemini (G5 and G6) surfactant induced β-sheet to α-helix transition in concanavalin A protein., Journal of Molecular Liquids, 269, (2018), 796-804
33. Hisamuddin M, Tazeen A, Abdullah M, Islamuddin M, Parveen N, Islam A, Faizan MI, Hamza A, Naqvi IH, Verma HN, Ajamaluddin Malik, Ahmed A, Parveen S. Co-circulation of Chikungunya and Dengue viruses in Dengue endemic region of New Delhi, India during 2016.. Epidemiol Infect. (2018) Jul 10:1-12.
32. Mohamad Alhasan Ismael, Javed Masood Khan, Ajamaluddin Malik, Mohammad Alsenaidy, Syed Hidayathulla , Rizwan Hasan Khan, Priyankar Sen, Mohammad Irfan, Abdulrahman Alsenaidy . Unraveling the molecular mechanism of sodium dodecyl sulfate, salts, and sugars into amyloid fibril formation in camel IgG. Colloids Surf B Biointerfaces. 2018 Jun 19;170:430-437.
31. Hesham Saeed, Mohammad Ismaeil, Amira Embaby, Farid Shokry Ataya,
Ajamaluddin Malik, Manal Shalaby, Sabah El-Banna, Ahmed Abdelrahim
Mohamed Ali, Khalid Bassiouny. Overexpression, purification and enzymatic characterization of a recombinant Arabian camel Camelus dromedarius glucose-6-phosphate dehydrogenase. Protein Expr Purif. 2018 Feb;142: 88-94.
30. Nasser Al-Shabib, Javed Khan, Ajamaluddin Malik, Abdulrahman M Alsenaidy, Mohammad A. Alsenaidy, Fohad Mabood Husain, Monis Bilal Shamsi, Rizwan Khan. Negatively charged food additive dye "Allura Red" rapidly induces SDS-soluble amyloid fibril in beta-lactoglobulin protein. International Journal of Biological Macromolecules. 107 (2018) 1706–1716
29. Farid S. Ataya, Dalia Fouad, Ajamaluddin Malik, Nikolaos E. Labrou,
Mohamed S. Daoud and Hesham Mahmoud Saeed. Cloning, Expression and Molecular Characterization of Glutathione Transferase P1-1 Gene from the Camel, Camelus dromedaries. Pakistan J. Zool., 2017, vol. 49(6), 2279-2289.
28. Ajamaluddin Malik, Shurog Albogami, Abdulrahman M. Al-Senaidy, Abeer M. Aldbass, Mohammad A. Alsenaidy, Shams Khan.  Spectral and thermal properties of novel eye lens ζ-crystallin. International Journal of Biological Macromolecules. 2017, 102: 1052–1058
27. Ajamaluddin Malik, Mohammad A. Alsenaidy. “MERS‐CoV papain-like protease (PLpro): Expression, Purification and Spectroscopic/Thermodynamic Characterization” 3Biotech 2017 Jun;7(2):100.
26. Mohd Shahnawaz Khan, Anwar Ahmed, Shams Tabrez, Badar ul Islam, Nayyar Rabbani, Ajamaluddin Malik, Mohammad Hasan Ismail, Mohammad A. Alsenaidy and Abdulrahman M. Alsenaidy. Optimization of expression and purification of human mortalin (Hsp70): folding/unfolding analysis. Spectrochim Acta A Mol Biomol Spectrosc. 2017 Dec 5;187:98-103.
25. Anwar Ahmed, Mohammed Arshad, Ajamaluddin Malik, Shama Parveen, Abdulrahman M. Alsenaidy, Camelus dromedarius glucose transporter 4: In silico analysis, cloning, expression, purification and characterization in E. coli. Archives of Physiology And Biochemistry. 2017 Apr 25:1-11
24- Shams Khan; Ajmaluddin Malik; Rizwan Wahab; Javed Ahmad; Omar Abd-Elkader; Javed Musarrat; Abdulaziz Al-Khedhairy “Synthesis and characterization of some abundant nanoparticles, their antimicrobial and enzyme inhibition activity”. Acta Microbiologica et Immunilogica Hungarica. 2017 Feb 20:1-14.
23. Mohd Shahnawaz Khan, Nayyar Rabbani, Shams Tabrez, Islam B, Ajamaluddin Malik, Anwar Ahmed, Mohammad A Alsenaidy, Abdulrehman M Alsenaidy. Glycation induced generation of amyloid fibril structures by glucose metabolites. ” Protein Pept Lett. 2016 23, 892-897.
22- Fereniki Perperopoulou, Farid S. Ataya, Dalia Fouad, Ajamaluddin Malik,
Hesham Mahmoud Saeed, Nikolaos E. Labrou. Biochemical Characterization of the Detoxifying Enzyme Glutathione Transferase P1-1 from the Camel Camelus Dromedarius. Cell Biochem Biophys (2016), 74 (4): 459–472
21- Ajamaluddin Malik, Mohammad Rabbani, Nayyar Rabbani, Abdulrahman M. Al-Senaidy, Mohammad A. Alsenaidy “Expression, Purification and Properties of Redox-Sensitive Eye Lens Zeta-Crystallin of Arabian Camel” Protein & Peptide Letters 2016, 23(6):573-80.
20- Ajamaluddin Malik, Farid S. Ataya, Dalia Fouad, Nikolaos E. Labrou Abdulrahman M. Al-Senaidy, Mohamad A. Ismael. Structural and thermodynamic properties of kappa class glutathione transferase from Camelus dromedarius. International Journal of Biological Macromolecules (2016) 88: 313–319.
19- Ajamaluddin Malik. Protein fusion tags for efficient expression and purification
of recombinant proteins in the periplasmic space of E. coli. 3Biotech. (2016) 6:44
18- Ajamaluddin Malik, Abdulrahman M. Alsenaidy, Mohamed Elrobh, Wajahatullah Khan, Mohammed S. Alanazi, Mohammad D. Bazzi “Optimization of expression and purification of HSPA6 protein from Camelus dromedaries in E. coli” Saudi Journal of Biological Sciences (2016) 23, 410–419
17-Anwar Ahmad, Ajamaluddin Malik, Haseeb Jagirdar, Nayyar Rabbani, Mohd Shahnawaz Khan, , Abdulrahman M. Al-Senaidy, Mohamad A. Ismael” Copper Induced Inactivation of Camel Liver Glutathione S-Transferase” Biological Trace Element Research (2016) 169:69-76.
16. Ajamaluddin Malik, Abuzar Haroon, Haseeb Jagirdar, Abdulrahman M. Alsenaidy, Mohamed Elrobh, Wajahatullah Khan, Mohammed S. Alanazi, Mohammad D. Bazzi  “Spectroscopic and thermodynamic properties of recombinant heat shock protein A6 from Camelus dromedaries” Eur Biophysics Journal (2015), 44(1-2):17-26
15. Ajamaluddin Malik*, Haseeb Jagirdar, Nayyar Rabbani, Mohd Shahnawaz Khan, Anwar Ahmad, Abdulrahman M. Al-Senaidy, Mohamad A. Ismael. “Optimization of storage and stability of camel liver glutathione s-transferase” (2015) Prep. Biochem Biotech- Oct 3; 45 (7):650-66.
14- Ajamaluddin Malik, Antje Mueller-Schickert & Bardwell JCA (2014) “Cytosolic selection systems to study protein stability” J Bacteriology, 196(24):4333-43
13- Wael M. Abdel-Mageed, Soad A.H. Bayoumi,Caixia Chen, Christopher J. Vavricka, Li Li, Ajamaluddin Malik, Huanqin Dai, Fuhang Song, Luoqiang Wang, Jingyu Zhang, George F. Gao, Yali Lv, Lihong Liu, Xueting Liu, Hanaa M. Sayed, Lixin Zhang. (2014)  “Benzophenone C-glucosides and gallotannins from mango tree stem bark with broad-spectrum anti-viral activity”. Bioorganic & Medicinal Chemistry. 22: 2236–2243
12- Ajamaluddin Malik, Abdulrahman Al-Senaidy, Ewa Skrzypczak-Jankun, Jerzy Jankun (2013) “Isolation and characterization of serum albumin from Camelus dromedarius” Experimental and Therapeutic Medicine. 6(2): 519-524.
11- Mohammad D. Bazzi, Mushari Quazani, Nayyar Rabbani, Ajamaluddin Malik, Mohammed Al Hasan, Mohammed S. Elrobh and Abdulrahman M. Al Senaidy (2013) Glycated Hemoglobin in camel: Minimal correlation with blood glucose level. Arch. Biol. Sci. 65 (3): 911-917.
10- Ajamaluddin Malik, Abdulrahman Al-Senaidy, Ewa Skrzypczak-Jankun, Jerzy Jankun. (2012) A study of the anti-diabetic agents of camel milk. Int. J. Mol. Med. 30(3): 585-92.
9- Farid S. Ataya, Dalia Fouad, Ebtsam Al-Olayan, Ajamaluddin Malik (2012) Molecular Cloning, Characterization and Predicted Structure of a Putative Copper-Zinc SOD from the Camel, Camelus dromedaries.  Int. J. Mol. Sci.  13: 879-900
8- Farid S. Ataya, Dalia Fouad, Ajamaluddin Malik, Hehsam M.Saeed (2012)
Molecular Cloning and 3D Structure Modeling of APEX1, DNA Base Excision Repair Enzyme from the Camel, Camelus dromedarius Int. J. Mol. Sci, 13(7): 8578-8596.
7. Ajamaluddin Malik, Marco Jenzsch, Andreas Lubbert, Rainer Rudolph & Brigitte Söhling (2007) “Periplasmic production of native human proinsulin as a fusion to E. coli ecotin ” Protein Expression and Purification, 55:100-11.
6. Ajamaluddin Malik, Rainer Rudolph & Brigitte Söhling (2006) “A novel fusion protein system for the production of native human pepsinogen in the bacterial periplasm”. Protein Expression and Purification, 47: 662–671
5. Ajamaluddin Malik, Rainer Rudolph & Brigitte Söhling (2005) “Use of enhanced green fluorescent protein to determine pepsin at high sensitivity”, Analytical Biochemistry. 340: 252-258
4. Ajamaluddin Malik, Asad U.Khan, and S.K.Lal. (2002) “Chemoprotection profiles of Sodium Thiosulfate on Methyl Methane Sulfonate induced mutagenesis of bacteriophage T4” Medical Science Monitor, 8(6): 212-220
3. Asad U. Khan, Ajamaluddin Malik and Masood Ahmad. (2001) “A unique and self splicing intron in bacteriophage T4” Indian Journal of Biochemistry and Biophysics, 38: 289-293.
2. Ajamaluddin Malik, Mohd. Afzal Khan and Asad U. Khan (2000) “Prevalence of multiple antibiotic resistance and R-plasmid in E.coli isolates of hospital sewage of Aligarh city in India” Indian Journal of Clinical Biochemistry, 15(2):27-32.
1. Asad U. Khan, Ajamaluddin Malik, Mohd. Afzal Khan and Aabgeena Naeem. (1999) “Analysis of multiple drug resistance in the E. coli of sewage and drinking water collected from domestic area of Aligarh city.” J. Microb. World, 1(2): 29-32.
 
RESEARCH PROJECTS
 
1- NPST project titled “Elucidation of unfolding-refolding mechanism of wild type and mutants of camel eye lens protein zeta-crystallin”
Project no: 12-MED2932-02;
Status-Ongoing
 
2- NPST project titled “Chaperones and Proteases in the quality control of protein misfolding disease”
Project no: 12-MED2928-02;
Status-Ongoing
 
3- KACST project titled “Overexpression and purification of recombinant camel Heat Shock Protein 6”
Project no: A-C-11-0606;
Status-completed
 
4- KACST project titled “Optimization of expression and purification of Camelus dromedaries glucose transporter 4 (GLUT4) in E.coli and its purification”.
Project no: M-P- 35-80;
Status- completed
 
5- NPST project titled “Development of a protein folding biosensor to study protein misfolding diseases”
Project no: 13-BIO843-02;
Status-Accepted
 
 
 
EDITORIAL and PEER-REVIEW ACTIVITIES
• Journal reviewer for Protein Expression and Purification
• Journal reviewer for International Journal of Health Sciences
• Journal reviewer for International Journal of Biological Macromolecules
• Journal reviewer for Current Protein & Peptide Science
• Book reviewer entitled “Molecular and Therapeutic actions of Thymoquinone
• Editorial board member of Biotechnology and Molecular Biology Reviews
 
ORAL  and POSTER PRESENTATION
6. “Optimization of protein folding in the cell”
Midwest Stress Response & Molecular Chaperone Meeting, Northwestern University, Evanston, USA (Jan 17, 2009)
5. “Optimization of protein folding in the cell”
FASEB summer research conferences, Vermont, USA (July 27-Aug 1, 2008)
4. “A new fusion protein system for the production of recombinant proteins in the bacterial periplasm” 19th Faltertage, Halle, Germany (22-24 September 2006)
3. “A new fusion protein system for the production of recombinant proteins in the bacterial periplasm” 5th Biotechnology symposium, Leipzig, Germany (18-19 May 2006)
2. “A new fusion protein system for the production of recombinant proteins in the bacterial periplasm” The protein engineering submit 2006, Boston, USA (24-28 April 2006)
1. “A novel fusion protein system for the production of human pepsinogen in the periplasm of E. coli” 18th Faltertage, Wittenberg, Germany (7-9 April 2005)
 
WORKSHOPS/TRAINING/WEBINAR
 
18- Conducted one month comprehensive training course on “Expression, Purification and Characterization of Proteins”, organized by Protein Research Chair, King Saud University (July 17-Aug 07,  2016).
17- Conducted one month comprehensive training course on “Expression, Purification and Characterization of Proteins”, organized by Protein Research Chair, King Saud University (July 26-Aug 20, 2015).
16- Conducted one month advance training course on “Protein Production and Characterization”, organized by Protein Research Chair, King Saud University (June 08-July 03, 2014).
15- Conducted one month advance training course on “Basic protein chemistry techniques”, organized by Protein Research Chair, King Saud University (June 23-July 18, 2012).
14- Participated four days long training program on “Ettan 2-D Electrophoresis course and Protein purification on Akta system” organized by GE healthcare at Protein Research Chair, King Saud University (Sept 29- Oct 02, 2012).
13- Attended workshop on “securing the fundamentals in PCR”, organized by Eppendorf in Dec 2012.
12- Attended two days conference “The Saudi International Biotechnology Conference 2012” organized by King Abdulaziz City for Science and Technology (Sept 18-19, 2012).
11- Conducted two days’ workshop on Basic protein chemistry techniques, organized by Protein Research Chair, King Saud University (May 14-15, 2011).
10- Conducted four days’ workshop on Protein purification: Principles and Practices, organized by Protein Research Chair, King Saud University (Feb 26- Mar 01, 2011).
9. Conducted two days’ workshop on Protein purification: Principles and Practices, organized by Protein Research Chair, King Saud University (Dec 27-28, 2010).
8. Attended Science Webinar on “From Genes to Proteins: The Impact of Gene Sequence on Translation and Expression” on October 28, 2009.
7. Attended Michigan Regional Meeting, on “Career Roadmaps for Postdocs” organized by University of Michigan, USA (October 10, 2009)
6. Successfully completed the “Occupational safety and environmental health
programs”, Organized by University of Michigan, USA (2007).
5. Attended national symposium on “Stability and Stabilization of Biomolecules”, Organized by Interdisciplinary Biotechnology Unit, Aligarh Muslim University, India (March 13-14, 2001)
4. Participated in “National Science Day” Organized by Interdisciplinary Biotechnology Unit, Aligarh Muslim University, India (February 28, 2000)
3. Participated in “National Science Day” Organized by Interdisciplinary Biotechnology Unit, Aligarh Muslim University, India (February 28, 1999)
2. Participated in “National Science Day” Organized by Interdisciplinary Biotechnology Unit, Aligarh Muslim University, India (February 28, 1998)
1. Attended “International conference on Molecular Association”, Organized by Department of Chemistry, Aligarh Muslim University, India (May 31, 1996)
 
 
 
 
 
 
 
PROFESSIONAL  MEMBERSHIP
• Member of American Association for the Advancement of Science (AAAS).
• Member of National Postdoctoral Association, USA
 
 
TEACHING  &  RELATED  ACTIVITIES
 
2016-2017: Mentored Master student research project entitled “Elucidation of the role of camel lens alpha crystalline in the folding and stability of zeta crystallin”, King Saud University, Saudi Arabia
2015-2016: Mentored Master student research project entitled “Purification and characterization of recombinant camel lens zeta (ζ)- crystallin”, King Saud University, Saudi Arabia
2014-2015: Mentored 497 student on “Urea induced denaturation study of yeast alcohol dehydrogenase by circular dichroism”, King Saud University, Saudi Arabia
2014-2015: Mentored 497 student on “Urea induced conformational changes in myoglobin”, King Saud University, Saudi Arabia
2013-2014: Mentored 497 student on “Urea induced denaturation study of camel serum albumin by circular dichroism”, King Saud University, Saudi Arabia
2011-2012: Mentored 497 student on “Development of new method for the
purification of camel serum albumin”, King Saud University, Saudi Arabia
2009-2010: Mentored Ph.D. student on “Novel genetic selection marker for directed evolution of proteins”, University of Michigan, USA
2007-2008 • MSc student was supervised to complete thesis. Titled “Development of a genetic selection to isolate protein mutants with improved expression and stability” University of Michigan, Ann Arbor, MI.
• Two students trained at under-graduate level.
2002-2007 Laboratory teaching and training of B.Sc and M.Sc in Biochem & Biotech. Students for “Recombinant protein expression and purification” Martin Luther University, Germany
2000-2002 Supervised M.Sc (Biotechnology) students to carry out experiments in the field of “Multiple-drug Resistance and Molecular Microbiology” in Aligarh Muslim University, India.