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CV

  CURRECULUM VITAE

Personal Details

Name:                        Abdulaziz Ali Al-Khedhairy

Nationality:             Saudi

Marital status:       Married

Address:                P.O. Box: 2455, Riyadh 11451,

Zoology Department, Faculty of Sciences,                             King Saud University, Riyadh, Saudi Arabia. 

E-mails:                 kedhairy@ksu.edu.sa

kedhairy@yahoo.com

Office Tel. :           0096614675765

Fax. No. :                0096614678514       

 

Academic Qualifications

  • PhD: Molecular Neurology - Biochemistry Department, Queens Medical Centre, Nottingham University, UK (1995).

·         Bachelor:  Biology - King Saud University, Riyadh, Saudi Arabia. (1990). 

Professional Details

·         2006 till now: Professor - Zoology Department, Faculty of Sciences, King Saud University, Saudi Arabia.

·         2002 – 2006: Associate professor - Zoology Department, Faculty of Sciences, King Saud University, Saudi Arabia.

·         1998 – 2002: Assistant professor - Zoology Department, Faculty of Sciences, King Saud University, Saudi Arabia.

·         1995 – 1998: Assistant professor - Faculty of Sciences, King Khalid Academy, Saudi Arabia.

·         1990 – 1995: Administrator - Faculty of Sciences, King Khalid Academy, Saudi Arabia.

Awards

 

·         Class Honour for bachelor degree.

·         Award of Excellent research project (First class) golden – King Abdulaziz City for Science and Technology (KACST), Riyadh, KSA.

 

Research Funds

v      Small funds

·         Characterisation of presenilin-1 cDNA of  rabbit (funded by King Abdulaziz City for Science and Technology, KACST, 2000)

·         Characterisation of presenilin-1 cDNA of  Arabian camel (funded by King Abdulaziz City for Science and Technology, KACST, 2002) 

v      Large Funds

·         Determination of point mutations in presenilin-1 from Saudi patients affected with Alzheimer disease (funded by King Abdulaziz City for Science and Technology, KACST, 2001)

·         Extraction, Authentication and Preservation of Genomes (DNA) of animals in the local habitat. (funded by King Saud University, 2004)

Conferences, Meeting and Training

·         Cell stress genes conference, 1995, Nottingham University, UK, (Poster).

·         The17th Saudi Biological Society meeting, 1996, Alqaseem, Saudi Arabia, (attendance).

·         The 19th Saudi Biological Society meeting, 1999, Jeddah, Saudi Arabia, (presented a paper).

·         Cell Structure and gene expression conference, 1999, Campbell Academy, New Hampshire, USA, (Poster).

·         Annual Conference of Union of Arab Biologists, 1999, Cairo, Egypt, (presented a paper).

·         Annual Conference of Union of Arab Biologists, 2002, Aleppo, Syria, (presented a paper).

·         International Seventh Symposium, Mutations on Genome, 2003, Cariens, Australia, (presented a paper).

·         Advanced training short course on Real-time PCR, 2005, Xiamen, China.

Society Membership

·         Saudi Biological Society.

·         Union of Arab Biologists.

·         BioMedNet for researchers in biology and medicine.

·         Editorial Board member of Advance Molecular Medicine, Turkey.

·         Editorial Board member of Arab Biotechnology, Egypt.

Communities and boards

·         Member of curriculum committee, Zoology Dept. (2005-present).

·         Member of purchase committee, Zoology Dept. (2005- present).

·         Representative of Zoology dept., academic accreditation board, College of Sciences. (2007 – present).

·         Member of scientific committee, Centre of Excellence in Biotechnology Research, King Saud University, (2007 – present).

·         Member of preparation committee for postgraduate studies in Mol. Biol. And genetic engineering programme, College of Sciences. (2006 – 2007).

·         Member of Zoology departmental board, since 1998.

·         Member of postgraduate studies committee, Zoology Dept. (2002-present).

·         Member of course time-table committee, Zoology Dept. (1990-2002).

·         Member of Faculty of Sciences departmental board, King Khalid Academy, (1995-1998).

 

University and community services

·         Teaching Undergraduate and postgraduate courses.

·         Supervisor for MSc and PhD students.

·         Participation in Saudi TV and Radio programs.

·         Speaker in general lectures inside and outside the university.

·         Editor-in-chief of Alam Alhyah, Saudi Biological Society, (2004 – 2007)

·         Worked as consultant – ministry of social affairs.

·         Visiting professor, Higher Institute for Security Sciences (NAUSS), March, 27, 2004 - May, 18, 2004.

·         Cooperation with Genetic Engineering and Biotechnology Program, King Abdulaziz City for Science and Technology (KACST), (1996 -2000)

·         Visiting professor, Naeif Arab University for Security Sciences (NAUSS), Nov., 11. 1999.

·         Writing articles in Al-jazirah Newspaper, Saudi Arabia, (1996 -2000).

Publications

Abd-Elsalam K.A., Roshdy S., Amin O.E., Rabani M. Y. (2010) First morphogenetic identification of Colletotrichum musae from imported Bananas in Saudi Arabia. African Journal of Biotechnology (Accepted).

 Quaiser Saquib, Abdulaziz A. Al-Khedhairy, Saud Al-Arifi, Braj Raj Singh, Jamal A. Arif, Javed Musarrat (2010) Genotoxic fungicide methyl thiophanate as an oxidative stressor inducing 8-oxo-7,8-dihydro-2’-deoxyguanosine adducts in DNA and mutagenesis, Journal of Environmental Science and Health, Part B Pesticides, Food Contaminants, and Agriculture, USA, 45, 1-6.

 

Braj R. Singh, Abdulaziz A. Al-Khedhairy, Saud A. Alarifi, Javed Musarrat (2010) Computational prediction of small non-coding RNA within distal 3’region of 16SrRNA gene of Bacillus sp. strain SJ-101. International Association for Computer sciences and Information Technology, IACSIT-SC 2009 Proceedings (Accepted)

 

Quaiser Saquib, Al-Khedhairy, A.A.; Al-Arifi,S., Alok Dhawan, Musarrat, J. (2009) Assessment of methyl thiophanate-Cu (II) induced DNA damage in human lymphocytes. Toxicology In vitro, Vol 23: 848-854. Elsevier; Pergamon Press, Oxford OX3 0BW, England ISSN: 0887-2333 IF: 2.473.

 Braj R. Singh, Abdulaziz A. Al-Khedhairy, Saud A. Alarifi, Javed Musarrat (2009) Computational identification of regulatory elements and coding sequence in 5’region of 16SrRNA gene of Bacillus sp. strain SJ-101, Bioinformation, 3 (9), 375-380, Biomedical Informatics Publishing Group, MI, USA.) Open Access Journal Online ISSN: 0973-2063; Print ISSN: 0973-8894.

 Musarrat, J.; Al-Khedhairy, A.A.; Alarifi, S., Khan, M.S. (2009) Role of 1-aminocyclopropane-1-carboxylate deaminase in Rhizobium-legume symbiosis In: Mohammed Saghir Khan, Almas Zaidi & Javed Musarrat (Eds), Microbial Strategies for Crop Improvement. Springer-Verlag, Germany, ISBN: 978-3-642-01978-4.

 

B. R. Singh, Aminuddin, A. A. Al-Khedhairy, Fahad Al-Qurainy, J. Musarrat (2009) Molecular diagnostics and phylogenetic analysis of Candidatus phytoplasma asteris (16SrI-Aster yellow group) infecting banana (Musa spp.) African Journal of Biotechnology, 8(21): Vol 8 (21): 5819-5824, Academic Press, ISSN 1684-5315 (IF 0.456).

 Afify AEMMR, Aboul-Soud MAM, Foda MS, et al. (2009) Production of alkaline protease and larvicidal biopesticides by an Egyptian Bacillus sphaericus isolate African Journal of Biotechnology: 8  (16): 3864-3873.

Yi, Z., Clamp, J., Al-Rasheid, K. A. S., Al Khedhairy, A. A., Chen, Z., Song, W. (2009) Evolutionary relationship and species separation of four morphologically similar stichotrichous ciliates (Protozoa, Ciliophora), Progress in Natural Science 19: 581–586 ISSN: 1745-5391 IF 0.083

Yi, Z., Song, W., Gong, J., Warren, A., Al-Rasheid, K. A. S., Al-Arifi, S., Al-Khedhairy, A. (2009). Phylogeny of six oligohymenophoreans (Protozoa, Ciliophora) inferred from small subunit rRNA gene sequences. Zoologica Scripta. 38(3): 323–331 Print ISSN: 0300-3256. Online ISSN: 1463-6409, IF 2.364

Li. L., Song. W., Shin, M.K., Warren, A., Al-Rasheid, K.A.S., Al-Khedhairy, A.A., Al-Arifi, S. (2009) Reconsideration of the phylogenetic positions of three stichotrichous genera Holosticha, Anteholosticha and Pseudokeronopsis (Spirotrichea: Ciliophora) inferred from complete SSU rRNA gene sequences. Progress in Natural Science 19: 769–773. ISSN: 1745-5391 IF 0.083

 M. Miao, W. Song, J.C. Clamp, K.A.S.Al-Rasheid, A. A. Al-Khedhairy, S. Alarifi (2009) Further Consideration of the Phylogeny of Some ‘‘Traditional’’ Heterotrichs (Protista, Ciliophora) of Uncertain Affinities, Based on New Sequences of the Small Subunit rRNA Gene. J. Eukaryot. Microbiol., 56(3), 2009 pp. 244–250.

Li ZC, Yi ZZ, Yang JP, et al. (2009) Phylogenetic investigation on five genera of tintinnid ciliates (Ciliophora, Choreotrichia), based on the small subunit ribosomal RNA gene sequences, Progress in Natural Science, 19 (9): 1097-110.

Yi ZZ, Song WB, Stoeck T, et al. (2009) Phylogenetic analyses suggest that Psammomitra (Ciliophora, Urostylida) should represent an urostylid family, based on small subunit rRNA and alpha-tubulin gene sequence information Zoological Journal of The Linnean Society: 157  (2): 227-236.

Kamel A. Abd-Elsalam*, Mohamed A. Moslem and Ali H. Bahkali (2009) First morpho-molecular identification of Rhizoctonia solani AG-7 from potato tuber-borne sclerotium in Saudi Arabia, African Journal of Microbiology Research, Vol. 3(12) pp. 952-956.

 Abd-Elsalam K.A., Bahkali H. A., Al-Khedhairy A. A. and Verreet H.-A. (2008) Development of a conventional and Lightcycler PCR assay for detection of Fusarium solani. Genes, Genomes and Genomics. 2:  63-67. (Japan)

Bahkali A. H.,  Abd-Elsalam K.A., Moslem M.A. and Al-Khedhairy A. A (2008) In-house protocol for isolation of restrictable and amplifiable genomic DNA from plants, fungi and bacteria. Genes, Genomes and Genomics, accepted. (Japan).

Gao, S., Song, W., Ma, H., Yi, Z., Clamp, J., Al-Rasheid, K. A. S., Al-Khedhairy, A. A. and Lin, X. (2008). Phylogeny of six genera of the Subclass Haptoria (Ciliophora, Litostomatea) inferred from sequences of small subunit rRNA genes. Journal of Eukaryotic Microbiology. 55. In press. (USA)

Miao, M., Song, W., Al-Rasheid, K. A. S., Al-Khedhairy, A., Al-Arifi, S. and Chen, X. (2008). Further consideration of the phylogeny of some Heterotrich Ciliates (Protista, Ciliophora) of uncertain affinities based on new sequences of the small subunit rRNA gene, with emphasis on six well-known genera. Journal of Eukaryotic Microbiology, 55. In press. (USA)

Li, L., Song, W., Shen, M-K., Stoeck, T., Al-Rasheid, K. A. S. and Al-Khedhairy, A. A. (2008). Reevaluation of the phylogenetic position of the highly ambiguous ciliate, Protocruzia (Protozoa; Ciliophora): based on multigene analyses, with suggestion of establishment of a new class Protocruziidea n. cl. Zoological Journal of the Linnean Society. In press. (UK)

Yi, Z., Song, W., Warren, A., Al-Rasheid, K. A. S., Al-Arifi, S., Al-Khedhairy, A., Wang, Y. and Zhang, Q. (2008). Phylogeny of six oligohymenophoreans (Protozoa, Ciliophora) inferred from small subunit rRNA gene sequences. Zoologica Scripta. 37. In press. (Norway)

Yi, Z., Song, W., Stoeck, T., Al-Rasheid, K. A. S., Al-Khedhairy, A., Gong, J., Ma, H. and Chen, Z. (2008). Phylogenetic analyses suggest that Psammomitra (Protozoa, Ciliophora, Urostylida) should represent a new family, based on SSrRNA and alpha-tubulin gene sequence information. Zoological Journal of the Linnean Society. In press. (UK)

Li, L., Zhang, Q., Hu, X., Warren, A., AL-Rasheid, K. A. S., Al-Khedheiry, A. A., Jiang, J. and Song, W. (2008). Morphology and infraciliature of a marine hypotrichous ciliate, Noviholosticha fasciola (Kahl, 1932) nov. gen., nov. comb. (Ciliophora: Urostylida) with notes on its SS rRNA gene sequence information. European Journal of Protistology. In press. (Germany)

Li, Z., Yi, Z., Gong, J., Clamp, J., AL-Rasheid, K. A. S., Al-Arifi, S., Al-Khedhairy, A., Chen, Z. and Song, W. (2008). Phylogenetic investigation on five genera of tintinnid ciliates (Ciliophora, Choreotrichia), based on the small subunit ribosomal RNA gene sequences. Progress in Natural Science. 18. In press. (China)

Al-Khedhairy, A. A. (2005) Molecular Characterization of a Polyubiquitin Gene from Duck, Anas platyrhnchos (Aves: Anatidae), Saudi J. Biol. Sciences, 12(1): 17-24. (Saudi Arabia)

Al-Khedhairy, A. A.,  Abdul Aziz Bin Dukhyil, Misbahul Arfin­­, Bassam A. Alahmadi, Saad M. Al-Rajeh, Mohamed A. Al-Jumah (2005)  Novel presenilin 1 mutation associated with early-onset Alzheimer’s disease in  Saudi patient, Neurosciences 10(4): 301-303. (Saudi Arabia)

Al-Khedhairy, A. A. (2005) Ubiquitin Primer Chip for Identification and Discrimination Genetic Materials.  Saudi J. Biol. Sciences, 12(2): 75-80. (Saudi Arabia)

Al-Khedhairy, A. A.,  Arfin M., Alahmadi B. A., Al-Jumah M. A. (2005) Single Nucleotide Polymorphism Associated with Late-onset Alzheimer’s Disease,  J. Medical Sciences 5(4): 275-279. (Pakistan)

Al-Khedhairy, A. A. (2004) Characterization of nucleotide sequence of a polyubiquitin gene (PUBC1) from Arabian camel, Camelus dromedarius. Biochem. Mol. Biol. , 37(2): 144-147. (Korea)

Al-Khedhairy A. A. (2004) Apolipoprotein E polymorphism as a predictor for cognitive decline and dementia in Saudi general population over 65 years old. Genetics and Molecular Biology. (2004), 27(3): 331-334.

Al-Khedhairy A. A. (2004) Apolipoprotein E polymorphism in Saudis. Molecular Biology Reports, (2004), 31(4): 257-260. (Netherlands)

Al-Khedhairy, A. A. (2003) Nucleotide Sequence of Presenilin-1 cDNA Fragment of Arabian Camel, Camelus dromedaries.  Arab Journal of Biotechnology 6(2): 165-172.

Al-Khedhairy, A. A. Al-Jumah M. A., Al-Rajeh S. M., Ibrahim E. R., Dukhyil A., Arfin M., Alahmadi B. A., Hardy J. (2003) Screening of PS1 mutations in a referral-based late-onset AD cases in Saudi Arabia. J. Medical Sciences 3(3): 209-213.

Al-Khedhairy, A. A. (2001) Quantitative RT-PCR Analysis of Polyubiquitin Gene Expression in Biomphalaria arabica After Exposure to Heat Stress and Cadmium. Pakistan J. Biol. Sci. 4(1): 103-106. (Pakistan)

Al-Khedhairy, A. A. Al-Rokayan, S.A. and Al-Misned, F.A. (2001) Cadmium Toxicity and Cell Stress Response. Pakistan J. Biol. Sci. 4(8): 1046-1049. (Pakistan)

Al-Khedhairy, A.A. (2000) Analysis of HSP70 Gene Expression in Biomphalaria arabica After Exposure to Cadmium. Egypt. J. Zool. 35: 151-161. (Egypt)

Al-Khedhairy, A. A. Arfin, M. and Dukhyil, A.A. (2002) Molecular cloning and sequencing of the rabbit presenilin-1 cDNA fragment Acta Biochimica Polonica 49(4): 1013-1017. (Poland)

Mayer, R. J., Tipler, C., Arnold, J., Laszlo, L., Al-khedhairy, A., Lowe, J. and Landon, M. (1996) Endosome-Lysosome, Ubiquitin and Neurodegeneration” Adv. Exp. Med. Biol. 389:261-269.

Al-Khedhairy, A. A. (1999) Acetone-Assisted Extraction and Qualitative Analysis of Genomic DNA of Three Snail Species from Saudi Arabia. J. Union Arab Biologists 11A: 1-11. 

Al-Khedhairy, A. A. (1999) Heat Stress Response in Human Foetal Lung MRC-5 Fibroblasts: Characterization of Gene Expression of Polyubiquitins, HSP70 and HSF1. J. Egypt. Ger. Soc. Zool. 28(A): 429-440.

 

Published Communicated/Under revision

1.         Quaiser Saquib, Abdulaziz A. Al-Khedhairy, Saud A. Alarifi,  Sansa Dutta, Swagata Dasgupta, Javed Musarrat (2010) Methyl thiophanate as a DNA minor grove binder produces MT-Cu(II)-DNA ternary complex preferably with AT rich region for initiation of DNA damage, International Journal of Biological Macromolecules. Manuscript No. IJBIOMAC-D-10-00003 (Under revision).

 

2.         Quaiser Saquiba, Abdulaziz A. Al-Khedhairya, Braj Raj Singha, Saud Alarifia, Jamal Mustafab, Javed Musarrat (2010) Preferential binding of a fungicide methyl thiophanate at sub-domain IIA of human serum albumin and induced conformational changes in protein, International Journal of Biological Macromolecules (Under revision).

3.          Azam, A. Ahmed A.S, Muhamed SM, Chaman, M., Naqvi, AH, Al-Khedhairy A>A> Musarrat, J (2009) Synthesis and Modulation of Structural and Optical Properties of Tin Oxide Nanoparticles. (2010) Material Science and Engineering B Manuscript ID: MSB-S-09-01654. (Under review).

4.          MA Siddiqui, MP Kashyap, VK Khanna, S Yadav , AA Al-Khedhairy, J Musarrat and AB Pant (2009) Protective potential of 17β-estradiol against co-exposure of 4-hydroxynonenal and 6-hydroxydopamime in PC12 cells, Toxicology Mechanisms and Methods. Manuscript ID: UTXM-2009-0097. (Under review)

5.          MA Sidiqui; M P Kashyap; V K Khanna; S Yadav; A A Al-Khedhairy; J Musarrat; Aditya Bhushan Pant (2009) Association of Dopamine DA-D2 Receptor in Rotenone Induced Cytotoxicity in PC12 Cells, Bulletin of Environmental Contamination and Toxicology. Manuscript Number: BECT2282R1(Under review)

6.          S. Dwivedi, A. A. Al-Khedhairy, B. R. Singh, S. Alarifi, J. Musarrat (2010) Isolation and characterization of butachlor catabolizing bacterial strain Stenotrophomonas acidaminiphila JS-1 from soil and assessment of its biodegradation potential, Letters in Applied Microbiology. Manuscript No.  (Under review).

7.      Javed Musarrat; Sourabh Dwivedi.; Abdulaziz A Al-Khedhairy; Braj R Singh,; Ameer Azam,; Alim A Naqvi (2010) Endophytic fungus Amylomyces rouxii strain KSU-09 isolated from date palm (Phoenix dactylifera)roots as a natural bioresource for production of silver nanoparticles, Bioresource Technology, Manuscript No.: BITE-D-10-00779 (Under review)

 

Total Presentations/Abstracts in Conferences/Symposia

1.       MA Siddiqui, AB Pant, Q Saquib, AA Al-Khedhairy, J Musarrat, and S Srivastava (2010) Metabolic fate of 4-Hydroxy Trans 2-nonenal in cultured PC-12 cells. Proceedings of 1st Annual Conference of Society of professional Biotechnologists, Kanpur, India.

2.       Javed Musarrat (2009) Pesticide DNA Interaction: A potential risk factor for Diabetes. Ist Saudi Diabetes Genome Study ‘SDGS” workshop, Strategic center, University Diabetes center, King Saud University, Riyadh, Saudi Arabia. (January 19-20, 2010).

3.       Javed Musarrat, Quaiser Saquib, Abdulaziz A.Al-Khedhairy, Saud Alarifi, Jamal M. Arif (2010) Genotoxic Fungicide Methyl thiophanate-Induced Oxidative DNA Damage and Mutagenesis. XXXV Annual Meeting of EMSI and International Symposium on Health and Agriculture, Chandigarh, india (March 12-14, 2010).

4.       Javed Musarrat, Quaiser Saquib, Abdulaziz A. Al-Khedhairy, Saud A. Alarifi, Maqsood Siddiqui (2010) Methyl thiophanate as a DNA minor grove binder produces MT-Cu(II)-DNA ternary complex preferably with AT rich region for initiation of DNA damage, 2nd International Conference of Biological and Environmental Sciences, (2nd ICBES), Mansoura University, Egypt (March 15-20, 2010)

5.       Sourabh Dwivedi, Abdulaziz A. Al-Khedhairy, Saud A. Alarifi, Braj Raj Singh, Javed Musarrat (2010) Isolation and characterization of butachlor catabolizing bacterial isolate Stenotrophomonas acidaminiphila strain JS-1 from contaminated soil and assessment of its biodegradation potential. 2nd International Conference of Biological and Environmental Sciences, (2nd ICBES), Mansoura University, Egypt (March 15-20, 2010).

6.       Braj Raj Singh, Abdulaziz A.Al-Khedhairy, Saud Alarifi, Javed Musarrat (2010) Computational Prediction of small non-coding RNA within distal 3’ regionof 16S rRNA gene of Bacillus sp strain SJ-101, The 2010 International Conference on Bioinformatics and Biomedical Technology (ICBBT 2010), Chengdu, China. (April 16-18, 2010)

7.       MA Siddiqui, MP, Kashyap, Q Saquib, AA Al-Khedhairy, Saud Alarifi, J Musarrat, AB Pant (2010) Prophylactic potential of Trans-resveratrol against 4-hydroxynonenal-induced damages in PC12 cells. Ist International Conference of Biological Sciences, Cairo, Egypt (September 27-29, 2010).

8.      Musarrat, J.; Al-Khedhairy, A. A.; Singh, B.R., Diwedi, S. and Saquib (2009) In-Silico Sequence Analysis and Molecular Modeling of hcn Genes in Pseudomonas aeruginosa Strain NJ-101 and Their Role in Antibiosis, The first International Conference on Biotechnology, Riyadh, SA (February 16-18, 2009). (Annexure-1)

9.      Musarrat, J.; Al-Khedhairy, A. A.; Singh, B.R., Diwedi, S and Azam A. (2009) Biosynthesis and Characterization of Protein-Capped Silver Nanoparticles using Fungus Fusarium oxysporum f. sp. Ciceri and their antibacterial potential.The International Conference for Nanotechnologies Industries (ICNI 2009), KSU, Riyadh (April 5-7, 2009).

  

 

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