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تحميل الدليل التدريبي

أسئلة شائعة


BCH 261 General Biochemistry

(For Dental Students)


September 2009 - June 2010



   This general biochemistry course is used to be divided into two courses:     BCH 261 and BCH 262 and were being taught specifically for the dental students. Because the College of Dentistry has changed their academic system into the yearly one instead of the semester system, these two courses have been evaluated as a one unit and being taught over  two semesters. Therefore, the course content reflects these two courses.



Course Content:

Dental biochemistry. Acid base dissociation, buffers. Amino acids and proteins, structure and function. Enzymes and cofactors. Carbohydrates, structures and metabolism. TCA cycle and electron transport system. Structure and metabolism of lipids and steroids. Biomembranes. Nutrition. Amino acid metabolism, transamination and the urea cycle. Protein biosynthesis, the role of DNA and the genetic code. Biochemistry of blood, haemoglobin, plasma proteins and immunoglobulins. Control and integration of metabolism (homeostasis). Connective tissues: collagen, the importance of vitamin C, keratin. Calcium and phosphorus metabolism.  Bone, cernentum and enamel  biochemistry. Dental diseases.  



Lectures : Sunday & Wednesday 1.30-2.00PM      Lecture Room AA 35 Bldg. 5

Lab       :  Tuesday            10.00 AM - 12.30 PM 

Labs AA 21, 25, 26 Bldg. 5

Tutorial :  Every Second Tuesday 10.00  - 11.30 AM    Lecture Room AA 35 Bldg. 5



Students are evaluated continuously throughout the semester, and are graded as follow:

  1. Short quizzes in each practical session                        15 Marks

  2. Mid First Semester examination of 2hours                    15 Marks

  3. Final First Semester written examination of 2 hours       25 Marks

  4. Year Final written lab examination of 1hours                   5 Marks

  5. Mid Second Semester examination of 2hours                15 Marks

  6. Final Second Semester written examination of 2 hours  25 Marks


Total                                                                             100 Marks




  1. Mid semester exam will be held on Thursday November 20th, 2009 at 10.00 AM Bldg.6

  2. Final written exam will be held according to the College of Science Exam TimeTable.

  3. For the Second Semester,  Mid semester exam will be held on Thursday April 9th, 2010 at 10.00 AM in Rooms Bldg. 6 




Biochemistry: The Molecular Basis of Life; McKee & McKee; 3ed Edition; McGraw Hill (2004)

In addition to the textbook, students are strongly advised to enhance their knowledge of the subject through the reading of the general biochemistry books such as Sryer's Biochemistry.


Detailed Course Content:

The following are the textbook chapters as they will be discussed throughout the two semesters. Hopefully, we will complete the first 16 chapters during the first semester, and the rest will be in the second semester.



UNIT I: Protein Structure and Function


    Chapter 1: Amino Acids 1

Chapter 2: Structure of Proteins 13 Chapter 3: Globular Proteins 25

Chapter 4: Fibrous Proteins 43

Chapter 5: Enzymes 53

UNIT II: Intermediary Metabolism

Chapter 6: Bioenergetics and Oxidative Phosphorylation 69

Chapter 7: Introduction to Carbohydrates 83

Chapter 8: Glycolysis 89 

Chapter 9: Tricarboxylic Acid Cycle 107

Chapter 10: Gluconeogenesis 115

Chapter 11: Glycogen Metabolism 123

Chapter 12: Metabolism of Monosaccharides and Disaccharides 135

Chapter 13: Pentose Phosphate Pathway and NADPH 143

Chapter 14: Glycosaminoglycans and Glycoproteins 155

UNIT III: Lipid Metabolism

Chapter 15: Metabolism of Dietary Lipids 171

Chapter 16: Fatty Acid and Triacylglycerol Metabolism 179

Chapter 17: Complex Lipid Metabolism 199

Chapter 18: Cholesterol and Steroid Metabolism 217

UNIT IV: Nitrogen Metabolism

Chapter 19: Amino Acids: Disposal of Nitrogen 243

Chapter 20: Amino Acid Degradation and Synthesis 259

Chapter 21: Conversion of Amino Acids to Specialized Products 275

Chapter 22: Nucleotide Metabolism 289

UNIT V: Integration of Metabolism

Chapter 23: Metabolic Effects of Insulin and Glucagon 305 Chapter 24: The Feed/Fast Cycle 319

Chapter 25: Diabetes Mellitus 335

Chapter 26: Obesity 347

Chapter 27: Nutrition 355

Chapter 28: Vitamins 371


UNIT VI: Storage and Expression of Genetic Information Chapter 29: DNA Structure and Replication 393

Chapter 30: RNA Structure and Synthesis 413

Chapter 31: Protein Synthesis 429

Chapter 32: Biotechnology and Human Disease 445


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