1. Synthesis of a Peptide Nucleic Acid with a Novel 1-Methyl-6-mercaptopurine Base, Tarek Aboul-Fadl, Gopalan Rajeev and Arthur D. Broom. J. Heterocyclic Chem., 45, 445-451 (2008).
2. Pre- and post-initiation chemoprevention activity of 2-alkyl/aryl selenazolidine-4(R)-carboxylic acids against tobacco-derived nitrosamine (NNK)-induced lung tumors in the A/J mouse. M. R. Franklin, P. J. Moos, W. M. El-Sayed, T. Aboul-Fadl, J.C. Roberts. Chem-Biol Interactions, 168, 211–220(2007).
3. Murine Hepatoma (Hepa1c1c7) Cells: A Responsive In Vitro System for Chemoprotective Enzyme Induction by Organoselenium Compounds. Wael M. El-Sayed, Tarek Aboul-Fadl, Jeanette C. Roberts, John G. Lamb and Michael R. Franklin. Toxicology in Vitro, 21, 157-164(2007).
4. Antisense Oligonucleotide Technologies in Drug Discovery. Tarek Aboul-Fadl, Expert Opin. Drug Discov. 1, 285-288(2006).
5. Susceptibility of Escherichia coli to L-selenaproline and other L-proline analogues in laboratory culture media and normal human urine. Charles Deutch, Maria Arballo, Latoya Cooks, Jenny Gomes, Tiara Williams, Tarek Aboul-Fadl and Jeanette Roberts, Letters in Applied Microbiology 43, 392–398(2006).
6. Acute Effects of Novel Selenazolidines on Murine Chemoprotective Enzymes. Wael M. El-Sayed, Tarek Aboul-Fadl, John G. Lamb, Jeanette C. Roberts, and Michael R. Franklin. Chemico-Biological Interactions, 162, 31-42 (2006).
7. Utility and Synthetic Uses of Mannich Reaction: An efficient Route for Synthesis of Thiadiazino-[1,3,5][3,2-a]Benzimidazoles. Abdel-Wareth A.O. Sarhan, Shams H. Abdel-Hafez, Hassan El-Sherif and Tarek Aboul-Fadl, Synthetic Communications, 36, 987 - 996 (2006).
8. Effect of selenium-containing compounds on hepatic chemoprotective enzymes in mice. Wael M. El-Sayed, Tarek Aboul-Fadl, John G. Lamb, Jeanette C. Roberts, Michael R. Franklin,Toxicology, 220, 179–188 (2006)
9. Synthesis of 5-Phenyl-1-(3-pyridyl)-1H-1,2,4-triazole-3-carboxylic Acid Derivatives of Potential Anti-inflammatory Activity. Safwat M. Rabea, Nawal A. El-Koussi, Hoda Y. Hassan, Tarek Aboul-Fadl, Archiv der Pharmazie, 339, 32-40(2006).
10. Preparation of prodrugs and conjugates of thiol- and selenol-containing compounds. Michael R. Franklin, Jeanette Roberts, Tarek Aboul-Fadl, U.S. Pat. Appl. Publ. (2005), 20 pp
11. Selenium Derivatives as Cancer Preventive Agents. ‘A Review Article’. Tarek Aboul-Fadl, Current Medicinal Chemistry-Anti-Cancer Agents, 5, 637-52 (2005).
12. Antisense Oligonucleotides: The State of the Art ‘A Review Article’. Tarek Aboul- Fadl, Current Medicinal Chemistry, 12, 2193-2214(2005).
13. Synthesis and Antitubercular Activity of Some Mannich bases Derived from Isatin Isonicotinic acid hydrazone. Mostafa A. Hussein, Tarek Aboul-Fadl and Asmaa Hussein, Bull. Pharm. Sci., Assiut University, 28, 131-136 (2005).
14. An Unusual “Senseless” 2’-5’ Oligoribonucleotide with Potent Anti-HIV Activity. Tarek Aboul-Fadl, Vijai K. Agrawal, Robert W. Buckheit Jr. and Arthur D. Broom, Nucleosides, Nucleotides & Nucleic Acids, 23, 545-554(2004).
15. Optical Isomers of 3-substituted-5-(2-carboxyethyl)-1,3,5- thiadiazin-2-thiones of Potential Antimicrobial Activity, Synthesis, and Solid State Stability. Mostafa A. Hussein, Tarek Aboul-Fadl, Mahrous Osman, Mohamed Hassan and Mohamed Hashem, Egyptian J. of Biomedical Sciences, 16, 194-209(2004).
16. Synthesis, Antitubercular Activity and Pharmacokinetic Studies of Some Schiff Bases Derived from 1- Alkylisatin and Isonicotinic Acid Hydrazide (INH). Tarek Aboul-Fadl, Fargany A. Mohammed and Ehssan A. Hassan, Archives of Pharmacal Research, 26, 778-784 (2003).
17. 1,2-Dihydroisoquinoline-N-Acetic Acid Derivatives as New Carriers for Specific Brain Delivery I : Synthesis and Estimation of Oxidation Kinetics Using Multivariate Calibration Method,Sahar Mahmoud, Tarek Aboul-Fadl, Mahmoud Sheha, Hassan H. Farag and Abdel-Maboud I. Mouhamed, Arch. Pharm.Pharm. Med. Chem., 336, 573-584 (2003).
18. 1,2-Dihydroisoquinoline-N-acetic acid Derivatives as New Carriers for Brain Specific Delivery II: Delivery of Phenethylamine as Model Drug, Sahar Mahmoud, Mahmoud Sheha, Tarek Aboul-Fadl, and Hassan H. Farag, Arch. Pharm.Pharm. Med. Chem.,336, 526-531(2003).
19. Synthesis, Degradation kinetics and In-vitro Antimicrobial Activity of Tetrahydro-2H-1,3,5- thiadiazine-2-thione Derivatives of Some b-Amino Acids, Tarek Aboul-Fadl and Abdel-Raouf Khallil, Arzneim-Forsch./Drug Res., 526-531(2002).
20. Tetrahydro-2H-1,3,5- thiadiazin-2-thione Derivatives of The optical Isomers of Phenylalanine, Synthesis, Comparative Stability Study and Antifungal Activity, Tarek Aboul-Fadl, and Mahrous Osman, Sci. Pharm., 70, 359-378(2002).
21. New 2H-Tetrahydro-1,3,5-thiadiazine-2-thiones Incorporating Glycine and Glycinamide as Potential Antifungal Agents, Tarek Aboul-Fadl, Mostafa A. Hussein, Abdel-Nasser El-Shorbagi, and Abdel-Raouf Khallil, Arch. Pharm.Pharm. Med. Chem.,335, 438-442(2002).
22. Kinetics of solid state stability of glycine derivatives as a model for peptides using null differential scanning calorimetry, Mostafa I. Abd-Elrahman, Mahrous O. Ahmed, Sayed M. Ahmed, Tarek Aboul-Fadl and A.El-Shorbagi, Biophysical chemistry, 19, 113-20(2002).
23. Di- and Trisubstituted Pyrazolo[1,5-a]pyridine Derivatives: Synthesis, Dopamine Receptor Binding and Ligand Efficacy. Stefan Löber, Tarek Aboul-Fadl, Harald Hübner and Peter Gmeiner, Bioorganic and Medicinal Chemistry Letters, 12, 633-636(2002).
24. New Paeonilactone-A-Adducts Formed by Incubation of Paeoniflorin with Lactobacillus brevis in Presence of Arylthiols, Atef A. Abdel-Hafez, Meselhy R. Meselhy, Norio Nakamura, Masao Hattori, Mahmoud A. El-Gendy, Nadia M. Mahfouz and Tarek A. Mohamed, Chem. Pharm. Bull., 49, 918-920(2001).
25. Antigiardial Activity of Metronidazole Twin Ester Prodrugs. Ahmed K. Dyab and Tarek Aboul-Fadl, Zagazig University Medical Journal, VII(5), 1268-1275(2001).
26. Investigation of Alkylating, Antineoplastic and Anti-HIV Potentials of the Chalcones; 2-(3-Arylpropenoyl)benzimidazole and Their Corresponding N1-Methyl Derivatives. Tarek Aboul-Fadl, Abdel-Nasser El-Shorbagi, Zeinab A. Hozien and Abdel-Wareth A.O. Sarhan, Bollettino Chimico Farmaceutico,139, 228-234(2000).
27. Effective and Variable Functionalization of Pyrazolo[1,5-a]pyridines Involving Palladium-Catalyzed Coupling Reactions. Tarek Aboul-Fadl, Stefan Löber and Peter Gmeiner, Synthesis,12, 1727-1732 (2000).
28. Cyclic amide derivatives as potential prodrugs: N-hydroxymethyl-succinimide- /isatin esters of some NSAIDs as chemical delivery system with improved therapeutic index, Omar, N. M. Mahfouz and T. Aboul-Fadl, Eur. J. Med. Chem.,34,551-562(1999).
29. Anticonvulsant Activity of Paeonimetabolin-I Adducts Obtained by Incubation of Paeoniflorin and Thiol Compounds with Lactobacillus brevis, Abdel-Hafez, M. R. Meselhy, N. Nakamura, M. Hattori, H. Watanabe, Y. Murakami. M. A. El-Gendy, N. M. Mahfouz and T. A. Mohamed, Biol. Pharm. Bull., 22,491-497(1999).
30. Tetrahydro-2H-1,3,5-thiadiazin-5-(4-pyridylcarboxamide)-2-thione Derivatives as prodrugs for Isoniazid, Synthesis, Investigations and In Vitro Antituberculous Activity, T. Aboul-Fadl and K. Hassanin, Pharmazie, 54, 244-247(1999).
31. Chitosan Conjugates of Ibuprofen and Flurbiprofen: Synthesis, Characterization and in vitro Stability, T. Aboul-Fadl, M. M. Sheha and S. Khider, Sci. Pharm., 67, 27-41(1999).
32. Metronidazole Twin Ester Prodrugs II : Non Identical Twin Esters of Metronidazole and Some Antiprotozoal Halogenated Hydroxyquinoline Derivatives, T. Aboul-Fadl and N. M. Mahfouz, Sci. Pharm., 66, 309-324
(1998).
33. Esters Twin Drugs of Metronidazole : Synthesis, Physicochemical properties, Kinetic studies and Antigardial activity, M. Mahfouz, T. Aboul-Fadl and A. K. Diab, Eur. J. Med. Chem., 33, 675-683(1998).
34. Effects of Paeoniflorin Derivatives on the Scopolamine-Induced Amnesia Using a Passive Avoidance Task in Mice; Structure-Activity Relationship, Abdel-Hafez, M. R. Meselhy, N. Nakamura, M. Hattori, H. Watanabe, Y. Murakami, M. A. El-Gendy, N. M. Mahfouz and T. A. Mohamed, Biol. Pharm.Bull., 21, 1174-1174(1998).
35. Paracetamol (Acetaminophen) Esters of Some Non-steroidal Anti-inflammatory Carboxylic acids Drugs as Mutual Prodrugs with Improved Therapeutic Index., T.A. Fadl and F. A. Omar, Inflammopharmacology, 6, 143-157(1998).
36. Potent Anticonvulsant Paeonimetabolin-I Derivatives Obtained by Incubation of Paeoniflorin and Sulfhydryl Compounds With Lactobacillus Brevis, Abdel-Hafez, M. R. Meselhy, N. Nakamura, M. Hattori, H. Watanabe, T. A. Mohamed, N. M. Mahfouz and M. A. El-Gendy, Chem.Pharm. Bull., 46,1486-1487(1998).
37. New Carriers for Representative Peptide Drugs, T. Aboul-Fadl and A. El-Shorbagi, Arch. Pharm.Pharm. Med. Chem, 330, 327- 332(1997).
38. Steric Parameters in PLE Catalyzed Hydrolysis of N4-substituted Cytarabine Esters Prodrugs, T. Kawaguchi, A.F.Youssef, T.Aboul-Fadl, F.A.Omar, H.H.Farag, and T.Hasegawa, Pharmazie, 51, 717-719(1996).
39. New Prodrug Approach for Amino Acids and Amino-Acid-Like Drugs, T.Aboul-Fadl and A. El-Shorbagi, Eur. J. Med. Chem.,31,165-169(1996).
40.Synthesis and In Vitro Investigation of Nalidixic Acid Amides of Amino Acid Esters as Prodrugs, T. Aboul-Fadl and E. A. Fouad, Pharmazie, 51, 30-33(1996).
41. Synthesis and Investigation of N4-substituted Cytarabine Derivatives as Prodrugs, T.A.Fadl, T.Hasegawa, A.F.Youssef, H.H.Farag, F.A.Omar and T.Kawaguchi, Pharmazie, 50, 382-387(1995).
42. 1HNMR and chelating properties of 1,5-dimethyl-N-substituted-1H-pyrazole-3- carboxamides and 1,3-dimethyl-N-substituted-1H-pyrazole-5-carboxamides, T.Abo-El-Fadl, A. F. Youssef and A. N. Ahmed, Pharmazie, 48,117-120(1993).
43. 1HNMR of Pyrazoles : effect of interaction of carbamoyl group with adjacent centers on the chemical shifts of concerned protons, T.A. Mohamed, A. F. Youssef and A. N. Ahmed, Bull. Pharm. Sci., Assiut University, 15, 100-105(1992).
44. Synthesis and Biological activity of certain 1,3- and 1,5-dimethyl-N-substituted pyrazole carboxamides, T.A. Fadl, A. F. Youssef, A. N. Ahmed and H. I. El-Bitar, Bull. Pharm. Sci., Assiut University, 13, 145-158(1990).