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COURSE SYMBOL AND NO    :  BCH 347

 

COURSE TITLE                           : METABOLISM (1)

 

CRIDIT HOURE                          : 3(3+0)

 

PREREQUISITE                           : BCH 221

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Course Description: 

Carbohydrate metabolism. Glycolysis and production of pyruvate. TCA cycle. Gluconeogenesis. Glycogenesis. Pentose phosphate pathway shunt & photosynthesis. Defects in carbohydrate metabolism. Digestion and absorption of lipids. Lipoprotein metabolism, lipogenesis and lipolysis in adipose tissue. Oxidation of fatty acids. Biosynthesis of fatty acids. Metabolism of triglycerides and phospholipids. Steroids metabolism. Defects in lipid metabolism.

 

LECTURE  NO                                       TOPICS 

1-2                             Digestion in the oral cavity salivary digestion intestinal digestion conversion of monosaccharide into D-glucose Absorption of carbohydrate in GI tract .

 

3-                                 Entry of glucose into cells. Phosphorylation of glucose into G-6-P and its  dephosphorylation in hepatic and kidney cells.

 

4-8                          Glycolytic pathway and production of pyruvate. Anaerobic metabolism of pyruvate oxidation of pyruvate into acetyl-coA. Control of glycolysis

 

9                                 Energetic of carbohydrate metabolism with a view of electron transport chain

 

10                                Anapolic sequence and conversing of amino acid into TCA cycle.

 

11-12                           gluconeogenesis  glycolate pathway

 

13-14                           glycogenesis

 

15-16                           pentose phosphate shunt

 

17-18                           photosynthesis

 

19-20                           Defect in carbohydrate metabolism

 

21-                               Digestion and absorption of lipids

 

22                                Lipogenesis in the adipose tissue

 

23-26                           Oxidation of fatty acid

 

27-                               Metabolism of ketone bodies- ketosis

 

28-31                           biosynthesis of fatty acids

 

32-33                           mitochondrial and microsomal chain elongation.

 

34-36                           metabolism of triglyceride, phospholipids and glycolipids.

 

37-                               Defects  in lipid metabolism.