COURSE SYMBOL AND NO : BCH 347
COURSE TITLE : METABOLISM (1)
CRIDIT HOURE : 3(3+0)
PREREQUISITE : BCH 221
Carbohydrate metabolism. Glycolysis and production of pyruvate. TCA cycle. Gluconeogenesis. Glycogenesis. Pentose phosphate pathway shunt & photosynthesis. Defects in carbohydrate metabolism. Digestion and absorption of lipids. Lipoprotein metabolism, lipogenesis and lipolysis in adipose tissue. Oxidation of fatty acids. Biosynthesis of fatty acids. Metabolism of triglycerides and phospholipids. Steroids metabolism. Defects in lipid metabolism.
LECTURE NO TOPICS
1-2 Digestion in the oral cavity salivary digestion intestinal digestion conversion of monosaccharide into D-glucose Absorption of carbohydrate in GI tract .
3- Entry of glucose into cells. Phosphorylation of glucose into G-6-P and its dephosphorylation in hepatic and kidney cells.
4-8 Glycolytic pathway and production of pyruvate. Anaerobic metabolism of pyruvate oxidation of pyruvate into acetyl-coA. Control of glycolysis
9 Energetic of carbohydrate metabolism with a view of electron transport chain
10 Anapolic sequence and conversing of amino acid into TCA cycle.
11-12 gluconeogenesis glycolate pathway
15-16 pentose phosphate shunt
19-20 Defect in carbohydrate metabolism
21- Digestion and absorption of lipids
22 Lipogenesis in the adipose tissue
23-26 Oxidation of fatty acid
27- Metabolism of ketone bodies- ketosis
28-31 biosynthesis of fatty acids
32-33 mitochondrial and microsomal chain elongation.
34-36 metabolism of triglyceride, phospholipids and glycolipids.
37- Defects in lipid metabolism.