EXPERIENCE AREAS
· Niosomes : preparation, evaluation and applications.
· Microspheres preparation for drug targeting.
· Bioavailability and Pharmacokinetics.
· Gamma-radiation and stability studies.
· Plasma protein binding.
· Solubilization and drug formulation.
· Transdermal drug delivery.
LIST OF PUBLICATIONS
"Preparation of Spherical Matrices of Prolonged-Release Ampicillin".
A.A. Bosela, M.A. Mahdy and E.A. Ibrahim.
The Pharmaceutical Society of Egypt 21 Conference of Pharmaceutical Sciences. Cairo, 1990.
" Bioavailability and In Vitro Evaluation of Microencapsulated Nitrofurantoin".
A.A. Bosela.
J. Bio. Med. Sci. Ther.; 7(1) 1991.
" Binding of Chlordiazepoxide Hydrochloride to Human Serum Albumin ".
A.A. Bosela, M.S. Treki and A.E. Aboutaleb.
J. Sci. Pharm. Austria, 59, 1991.
" Drug Release From Granules Containing Cellulose Acetate Phthalate as an Additive or Enteric Coating Material ".
A.A. Bosela, O.A. Sammour and M.A. Mahdy.
J. Bio. Med. Sci. Ther., 7, (4), 1991.
" Effect of Suspending Agent on the Dissolution and Bioavailability of Ampicillin ".
A.A. Bosela, M.S. Treki, M.A. Mahdy and M.S. Mohamed.
Bull. Pharm. Sci., Assiut Univ., 14(1) 1991.
" In Vitro Binding of Naproxen to Human Serum Albumin ".
M.A. Mahdy, O.A. Samour, A.A. Bosela and H.A. El-Ghamry.
Egypt. J. Appl. Sci., 6(10) 1991.
" Rectal Bioavailability of Chlorpheniramine Maleate From Different Suppository Bases".
O.A. Sammour, A.A. Bosela, H.A. El-Ghamry and M.A. Mahdy.
J. Bio. Med. Sci. Ther., 7, (8), 1991.
" An Investigation of Polyethylene Glycol and Povidone Effect on The Release of Benzocaine From Beeswax Films ".
M.S. Treki, A.A. Bosela and A.Y .Benkoura.
Egypt. J. Appl. Sci., 6(12) 1991.
" Stability of Chlordiazepoxide in Nonionic Micelles ".
A.A. Bosela.
Egypt. J. Appl. Sci., 7(1) 1992.
" The Effect of Certain Hydroxylated Additives and pH on Micellar Solubilization of Furosemide".
A.A. Bosela, O.A. Sammour and S.S. Abd Elhady.
Egypt. J. Appl. Sci., 7(3) 1992.
" Comparison of Ibuprofen –β-Cyclodextrin Inclusion Compounds and Solid Dispersion ".
O.A. Sammour, S.S. Abd Elhady, M.M. El-Sayed and A.A. Bosela.
Egypt. J. Appl. Sci., 8(3) 1993.
" Modulation of Pharmacokinetics of Tolbutamide and Acetohexamide xanthinol Nicotinate ".
A.M. Diab and A.A. Bosela. J. Bio. Med. Sci. Ther., 10 (9), 1994.
" Preparation of Targeted Isoniazid Microspheres ".
A.A. Bosela, M. El-Sayed and M. Mahmoud.
Al-Azhar 1rst Int. Conf. of Recent Adv. In Pharmaceutical Technology and Biological Sciences, Cairo, Dec. 1995.
" Enhancement of Dissolution and Absorption of Naproxen by Egg Albumin ".
A.A. Bosela and M. El-Sayed.
Al-Azhar 1rst Int. Conf. of Recent Adv. In Pharmaceutical Technology and Biological Sciences, Cairo, Dec. 1995.
" Effect of Plasticizers on the Physico-mechanical properties and Chlorphenesin Release From Eudragit Films ".
M. Salama, F. Ghazy, A.A. Bosela and A. Ismail
Zagazig J. Pharm. Sci. , 5(1) 1996.
" Improvement of Dissolution and Bioavailability of Khellin by Crystal Modification Technique ".
A.A. Bosela.
Bull. Fac. Pharm. Cairo Univ., 35(2), 163-169 , 1997
" In Vitro and Clinical Evaluation of Chlorphenesin Polymeric Films ".
M. Salama, F. Ghazy, A.A. Bosela and A. Ismail
Alex. J. Pharm. Sci. , 11(2) , 59-64, 1997.
" Transdermal Delivery of Khellin : In Vitro penetration Enhancement Through Rat Skin ".
A.A. Bosela.
Alex. J. Pharm. Sci. , 12(1) , 59-64, 1998.
" Comparative Study on Inclusion Complexation of Heptakis (2,6-di-O-methyl)- β-Cyclodextrin, β-Cyclodextrin and γ-Cyclodextrin with Ketoconazole in Aqueous Solutions and Solid state ".
A.A. Bosela and M. El-Sayed.
Zagazig J. Pharm. Sci. , 7(1) 87-93, 1998.
"Proniosomes as a Drug Carrier For Transdermal Delivery of Ketorolac."
I.A. Alsarra , A.A. Bosela , S.M. Ahmed and G.M. Mahrous.
European J. of Pharmaceutics and Biopharmaceutics, 59, 485-490,2005.
"Modulating Intestinal Uptake of Atenolol Using Niosomes as Drug Permeation Enhancers."
I.A. Alsarra , A.A. Bosela , A.M. Al-Mohizea , G.M. Mahrous and S.H. Neau.
Scientia Pharmaceutica (Austria) 73, 81-93, 2005.