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تحميل الدليل التدريبي

أسئلة شائعة


 

LIST OF PUBLICATIONS

                                                                          

1- Synthesis of 6-Aminophenanthridines from Some Thiourea Derivatives:

    A.-Mohsen M.E. Omar, N.S. Habib and Omaima M. AboulWafa, Pharmazie, 32,

    758 (1977).

 

2- Dicyclohexylcarbodiimide  as  an  Efficient  Cyclodesulfurizing  Agent  in  the        

    Synthesis of Heterocyclic Compounds from Various Thio-Compounds:

    A.-Mohsen M.E. Omar, N.S. Habib and Omaima M. AboulWafa,  Synthesis, 864

    (1977). 

 

3- Synthesis  of  Some 1-Substituted  Amino-3H-imidazo[1,5-a]Benzimidazole

    Derivatives  by  Cyclodesulfurization of  Various Benzimidazole  Thioureas  with

    Dicyclohexylcarbodiimide:

    A.-Mohsen M.E. Omar, N.S. Habib and Omaima M. AboulWafa, Pharmazie, 35,

    798 (1980). 

 

4- Novel Potential Alkylating Agents Derived from Benzimidazole and Benzothiazole

    A.-Mohsen  M.E. Omar, N.S. Habib  and  Omaima  M. AboulWafa, J. Pharm. Sci.,

   71, 991 (1982).

 

5- Novel 2'-Substituted Amino-17-oxoestra-1(10),4-dieno[2,3-d]oxazole and Estra-

    1,5(10)-dieno[4,3-d]oxazole Derivatives: Synthesis and in vitro Anabolic-Catabolic

    Activities:                                                                                      

    El-Sebai A. Ibrahim, A.-Mohsen  M.E. Omar, N.S. Habib, Omaima  M. AboulWafa

    and J. Bourdais, J. Heterocyclic Chem., 19, 761 (1982).

·         Presented  in Part at  the 8th  International Congress of  Heterocyclic Chemistry,

    held in Graz, Austria, August 1981.

 

 

 

 

                                                                            Omaima  M.AboulWafa,Ph.D.    

                                                                            Page 1

6-Steroidal Oxazoline Derivatives: Synthesis and in vitro Effect on Bovine Pancreatic

    Ribonuclease Activity:

    A.-Mohsen  M.E.Omar  and  Omaima  M.  AboulWafa,  J. Pharm. Sci., 71, 983 

    (1982).

 

 7- Steroidal Thiourea and Thiazoline  Derivatives: Synthesis and  in vitro  Effects on

     Bovine Pancreatic Ribonuclease Activity:

     El-Sebai A. Ibrahim, A.-Mohsen  M.E.Omar, N.S. Habib, Omaima M. AboulWafa,

     S.M. El-Sewedy  and  J.  Bourdais, J. Pharm. Sci., 72, 1205 (1983).

    *Presented  in Part at  the Medicinal Chemistry Congress held in USA, August

    1981.

 

8- Novel Phenanthridine Thiosemicarbazone  and  Thiazoline  Derivatives: Synthesis

     and Evaluation for Anticancer and Antimicrobial Activities:

     A.-Mohsen M.E.Omar  and  Omaima  M. AboulWafa, Archiv der Pharmazie, 317,

     668 (1984).

 

9- Synthesis and Evaluation of Novel N-Substituted-N'-(3-Hydroxy-17-oxoestra-1,3,5

    (10)-trien-2- and 4-yl)thiourea  Derivatives for  Binding  to  the  Estrogen  Receptor

    and Cytotoxic Activity on  MCF-7 Cells:

    A.-Mohsen  M.E.Omar  and  Omaima  M.  AboulWafa,  J. Pharm. Sci., 73, 1871 

    (1984).

 

10- Synthesis  and  Anticonvulsant  Properties of  a  Novel Series of  2-Substituted

      Amino-5-aryl-1,3,4-oxadiazole Derivatives:

      A.-Mohsen  M.E.Omar  and  Omaima  M.  AboulWafa, J. Heterocyclic Chem.,      

     21, 1415 (1984).

 

11- Novel  Estradiol-17-α-1,2,4-Triazole  Derivatives: Synthesis  and  in  vitro   

       Anabolic-Catabolic  Properties  and  Binding  Affinity  to  Steroid  receptors:

      A.-Mohsen  M.E.Omar  and  Omaima  M.  AboulWafa, J. Heterocyclic Chem.,           

      21, 1419  (1984).                 

                                                                                   Omaima  M.AboulWafa,Ph.D.    

                                                                        Page 2

12- Novel 2'-Substituted Amino-3-methoxy-16  -bromo-17-oxoestra-1,3,5(10)-

     dieno[1,2-b]thiazoles:                                                              

     A.-Mohsen  M.E.Omar  and  Omaima  M.  AboulWafa, J. Heterocyclic Chem.,           

     21, 1665  (1984).

     * Presented in Part at the 9th International Congress of Heterocyclic Chemistry           

      held in Tokyo, Japan.

 

13- Synthesis and in vitro Antimicrobial and Antifungal Properties of Some Novel

     1,2,3-Thiadiazole and s-Triazolo[3,4-b][1,2,3]Thiadiazole Derivatives:

     A.-Mohsen  M.E.Omar  and  Omaima  M.  AboulWafa, J. Heterocyclic Chem.,           

     21, 1665  (1984).

    

14-Synthesis of N-Glycylthiazolidine Derivatives as Radioprotective Agents:

     Omaima M. AboulWafa, Joel Oiry, Jean-Louis Imbach and Marc Fatome,

     Eur. J. Med. Chem., 21, 493 (1986). 

 

15- Synthesis of 2-Arylamino-1-(1-naphthyl)imidazolines by Cyclodesulfurization of

     Some Ethylenediamine thiourea Derivatives with DCCD:

     A.-Mohsen  M.E.Omar  and  Omaima  M.  AboulWafa, Alex. J. Pharm. Sci., 2, 21

     (1988).           

 

16- Synthesis of Some Substituted Benzimidazoles with Potentioal Antimicrobial

     Activity:

     Ibrahim M. Labouta, Ahmed M. Hassan, Omaima M. AboulWafa and Ola A.

     Kader, Monat. Chem., 120, 571 (1989).

 

17- Synthesis of 2-Substituted Amino-5-(2,5-dihydroxyphenyl)-1,3,4-Thiadiazoles,

    1,3,4-Oxadiazoles and Their Oxidation Products as Potential Antimicrobial Agents:

    S.M. El-Khawass, I. Chaaban, Omaima M. AboulWafa and A.A. Hazzaa, Acta

    Pharm. Jugosl., 39, 143 (1989).

 

                                                                                   

                                                                                    Omaima  M.AboulWafa,Ph.D.     

                                                                         Page 3

 18- Novel Thiosemicarbazones, Thiazolines and Thiazolidines Derived from

     Chalcones: Synthesis, Antimicrobial and Anticancer Properties:

     A.-Mohsen M.E. Omar, I. Chaaban, Omaima M. AboulWafa, Ahmed M. Hassan,

     Hamida Abou-Schleib and Khadiga A. Ismail, Alex. J. Pharm. Sci., 3, 211 (1989).

 

19- Synthesis and Evaluation for Antibacterial and Antifungal Activities of New 5-

     Dimethylamino-1-Aryl[and 1-(2-Furyl)]-1-penten-3-one-3-Substituted Thiosemi-

     carbazone Derivatives:

     A.-Mohsen M.E. Omar, I. Chaaban, Ahmed M. Hassan, Omaima M. AboulWafa,

     Hamida Abou-Schleib and Khadiga A. Ismail, Alex. J. Pharm. Sci., 3, 224 (1989).

 

20- Synthesis and Antimicrobial Activity of Novel Thiophene Derivatives:

     Omaima M. AboulWafa, Hamida Abou-Schleib and A.-Mohsen M.E. Omar, Alex.

     J. Pharm. Sci., 4, 168 (1990).

     * Presented in Part at the International Conference of Pharmaceutical industries

     held in Alexandria, Egypt, May 1990.

 

21- Synthesis and Evaluation for Antibacterial and Antifungal Activities of New 1-

     Phenylhydrazono-2-(Substituted Thiocarbamoyl)hydrazonopyruvaldehyde and the

    Corresponding Thiazoline and Thiazolidinone Derivatives:

    A.-Mohsen M.E. Omar, I.C. Chaaban, Ahmed M. Hassan, Omaima M. AboulWafa,

     Hamida Abou-Schleib and Khadiga A. Ismail, Alex. J. Pharm. Sci., 4, 182 (1990).

 

22- Synthesis of Novel Naphthalene and Naphth[1,2-d]oxazole Derivatives as

     Potential Antimicrobial Agents.Part I:

     Omaima M. AboulWafa, El-Sayeda M. El-Khawass and Hoda A. El-Shamy, Alex.

     J. Pharm. Sci., 5, 69 (1991).

 

23- Synthesis of 2-Ethoxycarbamoylbenzimidazoles, Benzoxazoles and 1,3,4-

     Oxadiazoles:

     A.-Mohsen  M.E.Omar  and  Omaima  M.  AboulWafa, Sulfur Letters ,14, 181

     (1992).

                                                                                Omaima  M.AboulWafa,Ph.D.    

                                                                      Page 4

     * Presented in Part at the 11th International Congress of Heterocyclic Chemistry           

      held in Federal Republic of Germany, July 1987.

 

24- Synthesis and Evaluation for Uterotrophic and Antiimplantation activity of 2-

     Substituted Estradiol Derivatives:

     Omaima  M.  AboulWafa, Mahmoud M. Mohy El-Din and A.-Mohsen M.E. Omar,

     Steroids,  57, 199 (1992).

     *Presented in Part at the International Conference of Pharmaceutical Industries

     held in Alexandria, Egypt, May 1990.

 

25- Benzo[b]thiophene Derivatives, Part I: Synthesis and Antimicrobial Activity of

     Benzo[b]thienyl-1,3,4-Oxadiazole, 1,3,4-triazole and Thiazoline Derivatives:

     Omaima M. AboulWafa and Fatma A.G. Berto, Archiv der Pharmazie      

     (Weinheim), 325, 123 (1992).

 

26- Benzo[b]thiophenes: Synthesis of Novel Benzo[b]thienylhydrazine and 1,3,4-

     Oxadiazole Derivatives as Potential Antidepresant Agents:

     Omaima M. AboulWafa and Mona A.E. El-Metwalli, Archiv der Pharmazie      

     (Weinheim), 325, 603 (1992).

 

27- Synthesis and Antimicrobial Activity of Some Thiazolinyltetrahydrobenzo[b]-

     thiophenes and Thiazolinyltetrahydrobenzothieno[2,3-d]pyrimidin-4-ones:

     Omaima M. AboulWafa, Khadiga A. Ismail and Essam A. Koreish, Il Farmaco,

     47, 631 (1992).

 

28- Synthesis of 3-Arylamino-1,2,4-triazolo[3,4-c]pyrimidino[4,5-b]tetrahydrobenzo-

     [b]thiophenes by Cyclodesulfurization of the Corresponding Thiocarbamoyl-

     hydrazinothieno[2,3-d]pyrimidine Derivatives:

     Khadiga A. Ismail and Omaima M. AboulWafa, Sulfur Letters, 15, 111 (1992).

 

 

 

                                                                                   Omaima  M.AboulWafa,Ph.D.    

                                                                        Page 5

 29- Synthesis, Binding Affinities and Uterotrophic Activity of Some 2-Substituted

     Estradiol and Ring-Fused Pyrone Derivatives:

     A.-Mohsen M.E. Omar, Ibrahim C. Ahmed, Omaima M. AboulWafa, Ahmed M.

     Hassan, Khadiga A. Ismail, Mahmoud M. mohy El-Din and Nabil A. Mansour,

     Eur. J. Med. Chem., 29, 25 (1994).

 

30- Synthesis of Novel Thiosemicarbazone Derivatives as Potential Antiestrogens:

     Alaa A. El-Tombary, Khadiga A. Ismail, Omaima M. AboulWafa, A.-Mohsen

     M.E. Omar and Safaa H. El-Reyini, Alex. J. Pharm. Sci., 9, 147 (1995).

     *Presented in Part at the International Conference of Pharmaceutical Sciences

     and Technology held in Alexandria, Egypt, March 1995.

 

31- Synthesis and Antimicrobial activity of Some Tetramethylenethieno[2,3-d]

     Pyrimidine Derivatives:

     Khadiga A. Ismail, Omaima M. AboulWafa and Essam A. Koreish, Il Farmaco,

     50, 611 (1995).

 

32- Synthesis and Biological Evaluation of Some 2-Pyrimidinylestradiol Derivatives:

     Alaa A. El-Tombary, Khadiga A. Ismail, A.-Mohsen M.E. Omar and Omaima M.

     AboulWafa, Eur. J. Med. Chem., 30, 423 (1995).

 

33- Synthesis, Estrogen Receptor Binding Affinity and Biological Evaluation of Some

     2-Thiazolylestrone and Estrono[17,16-d]Thiazole Derivatives:

     A.-Mohsen  M.E.Omar, Omaima  M.  AboulWafa, Ibrahim M. Labouta, Alaa A.

     El-Tombary and Ahmed I. El-Mallah, Alex. J. Pharm. Sci., 10, 19 (1996).

 

34- Novel Steroidal 1,4-Diketones and Pyridazine Derivatives as Potential Anti-

     estrogens:

     Khadiga A. Ismail, Alaa A. El-Tombary, Omaima M. AboulWafa, A.-Mohsen

     M.E. Omar and Safaa H. El-Reyini, Arch. Pharm.-Pharm. Med. Chem., 329,

     433 (1996).

 

                                                                                   Omaima  M.AboulWafa,Ph.D.    

                                                                        Page 6

     *Presented in Part at the International Conference of Pharmaceutical Sciences and

     Technology held in Alexandria, Egypt, March 1995.

 

35- 4',17-Dioxo-5'H-estra-1(10),4-dieno[3,2-b]Furan; Synthesis, Binding Affinity to

     the Estrogen Receptor, Uterotrophic and Antiimplantation Activities:

     A.-Mohsen  M.E.Omar, Omaima  M.  AboulWafa, Ibrahim M. Labouta, Alaa A.

     El-Tombary and Ahmed I. El-Mallah, Arch. Pharm.-Pharm. Med. Chem., 329,

     61 (1996).

       

36- Synthesis, Estrogen receptor Binding Affinity and Biological Evaluation of Some

     2-Substituted Estrone Derivatives:

     A.-Mohsen  M.E.Omar, Omaima  M.  AboulWafa, Ibrahim M. Labouta, Alaa A.

     El-Tombary and Ahmed I. El-Mallah, Il Farmaco, 52, 219 (1997). 

 

37- Synthesis and Antimicrobial Evaluation of Some Quinoxaline Derivatives:

     Alaa A. El-Tombary, Khadiga A. Ismail, Omaima M. AboulWafa and Essam A.

     Koreish, Alex. J. Pharm. Sci., 12, 27 (1998).

 

38- Novel Triazolo[4,3-a]quinoxalinones and Ditriazolo[4,3-a:4',3'-c]quinazolines:

     Synthesis and Antotoxoplasmosis Effect:

     Alaa A. El-Tombary, Khadiga A. Ismail, Omaima M. AboulWafa, Mervat Z. El-

    Azzouni and Salwa T. El-Mansoury,  Il Farmaco, 54, 486 (1999).

     *Presented in Part at 6th Ibn Sina International Conference on Heterocyclic

     Chemistry held in Cairo, Egypt, December 1997.

 

39- Synthesis of Novel Thienyl Hydrazones, Oxadiazolines, Thiosemicarbazides,

     Oxadiazoles, Thiazolines, Triazolines and Alkylthiotriazoles as Potential

     Antimicrobial agents:

     A.-Mohsen  M.E.Omar, Omaima  M.  AboulWafa, Ali A.B. Hazzaa and Sherine

     A.E. El-Samahy, Alex. J. Pharm. Sci., 18, 141 (2004).

   * Presented in Part at the 28th Conference of the Egyptian Pharmaceutical Society

    held in Cairo, Egypt, December 2002. 

                                                                                    Omaima  M.AboulWafa,Ph.D.    

                                                                                            Page 7

 40- Cytotoxic and  Antiproliferation  Effects  of  Two  New  Modified  Estrogens  in

     Estrogen-Independent  (MDA-MB-231)  Human  Breast  Cancer  Cell  Line  and

     Hep G2 Cancerous Liver Cell Line:

     Omaima M. AboulWafa, Prema Kupusamy, Supadhara A/P Ramaiyah and Zeinab 

     A. Hassan, Bull. Egypt. Soc. Physiol. Sci., 24, 126 (2004).

*Presented in Part at the 6th Saudi Pharmaceutical International Conference, held

 in Riyadh, KSA, October 2003.

 

41- Novel Triazole and Triazoline Derivatives Fused to Thieno[2,3-d]pyrimidin-

      5(4H)-one System as Potential Antimicrobial Agents:

      A.-Mohsen  M.E.Omar, Omaima  M.  AboulWafa, Ali A.B. Hazzaa and Sherine

      A.E. El-Samahy, Alex. J. Pharm. Sci., 19, 97 (2005).

      * Presented in Part at the 28th Conference of the Egyptian Pharmaceutical Society

      held in Cairo, Egypt, December 2002.

 

42- Synthesis of Some Tetrahydrobenzo[b]thieno[2,3-d]pyrimidinone Derivatives of

      Potential Pharmacologic Activities:

     Ahmed M. Farghaly, Omaima M. AboulWafa, Mona A. El-Semary, Adnan A.

     Bekhit and Mai S. El-Shoukrofy (Under Publication).

*Presented in Part at the 9th International Conference on Pharmaceutical Chemistry,

  held in Riyadh, KSA, December 2005.

 

44- Structural and Biochemical Studies of Metal Complexes with Estrone Derivatives:

      Sawsan M. Abo-Zeid, Maha Al-Kanbit and Omaima M. AboulWafa. (Under

      Publication).

     *Presented in Part at the 9th International Conference on Pharmaceutical

      Chemistry, held in Riyadh, KSA, December 2005.

 

45- Synthesis of Bioconjugate Analogs of Curcumin as Potent Antitumor Agents:

      Khairia M. Youssef, Omaima M.AboulWafa and Reem I. Al-Wably (Under

      Publication in Arch. Pharm.).

                                                                                     Omaima  M.AboulWafa,Ph.D.    

                                                                                             Page 8

     *Presented in Part at the 9th International Conference on Pharmaceutical

      Chemistry, held in Riyadh, KSA, December 2005.

 

46- Synthesis of Ring-A Substituted Estrogens of Potential Therapeutic Activity:

       Omaima M. AboulWafa, Maha S. Al-Mutairi, Khairia M. Youssef, Hussein I.

       Al-Subbagh, Omar A. Al-Deeb, Abir T. Al-Alfy and Amal J. Fatani.

       *Presented in Part at the 19th International Symposium on Medicinal Chemistry

         held in Istanbul, Turkey on August-September 2006.

 

47- Synthesis of Some Pharmacologically Active Tthieno[3,4-d]pyrimidinone

      Derivatives:

      Ahmed M. Farghaly, Omaima M. Aboulwafa, Mona A. El-Semary, Adnan A.

      Bekhit and Mai S. El-Shoukrofy.

*Accepted for presention in Part at the 7th Saudi Pharmaceutical International

  Conference, which will be held in Riyadh, KSA, March 2007.

 

48- Synthesis of Some 2- and 4-Peptidylestrone Derivatives of Potential Therapeutic

      Activity:

      Omaima M. AboulWafa, Maha S. Al-Mutairi, Khairia M. Youssef, Hussein I.

      Al-Subbagh, Omar A. Al-Deeb, Amal J. Fatani and Majed S. Al-Okail.

 *Accepted for presention in Part at the 7th Saudi Pharmaceutical International

   Conference, which will be held in Riyadh, KSA, March 2007.

 

49- Modified Estrogens: Synthesis of Alkylamino- and Alkylthioacetylaminoestrone

      Derivatives as Potential Anticancer Agents:

      Omaima M. AboulWafa, Khairia M. Youssef, AbdulRahman M. Al-Obeid and

      Majed Al-Okail.

*Accepted for presention in Part at the 7th Saudi Pharmaceutical International

   Conference, which will be held in Riyadh, KSA, March 2007.

 

 

                                                                                     Omaima  M.AboulWafa,Ph.D.    

                                                                                             Page 9

 
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