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تحميل الدليل التدريبي

أسئلة شائعة


Curriculum Vitae

 

 


Afaf K. El-Ansary

                                                        King Saud University (Dept. of Biochemistry)

                                                        P.O Box 22452, Zip Code 1149

                                                        Riyadh, Kingdom Of Saudi Arabia

                                                        Tel: 009661-4769137 ext. 1396

                                                        FAX: 009661-4769137

                                                        Email  : elansary@ksu.edu.sa

                                                                   : afafelansary@yahoo.com

 

ACADEMIC BACKGROUND:

B.Sc. (1974):         Biochemistry Department, Faculty of Science, Ain   Shams University, Cairo, Egypt.

M.Sc. (1980):        Biochemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt.

Ph.D. (1990):        Biochemistry Department, Faculty of Science, Ain  Shams University, Cairo, Egypt.

 

POSITION HELD

2002- Now:           Professor, Biochem. Dept. Faculty of Science, King Saud University,   Riyadh, Saudi Arabia.

2001-2002:            Professor, Faculty of Education, Jeddah, Saudi   Arabia

2000-2001:           Professor, Medicinal Chem. Dept. Nat. Res. Centre, Egypt.  

1995-2000:            Associate professor, Medicinal Chem. Dept. Nat.

1994-1995:            Researcher, Medicinal Chem. Dept. Nat. Res. Centre

1992-1994:            Assistant professor, Biochem. Dept. Faculty of Science King Saud University, Riyadh, Saudi Arabia.

1990-1992:             Researcher, Medicinal Chem. Dept. Nat. Res. centre Egypt.

1987-1990:            Assistant lecturer, Medicinal Chem. Dept. Nat. Res      centre. Egypt.  

1982-1987:            Demonstrator, Biochem. Dept. Faculty of Science, King Saud University, Saudi Arabia.

1976-1982:            Assistant researcher, Medicinal Chem. Dept. NRC Egypt.  

MEMBERSHIP

ü  Secretary of the Middle Eastern Society for Comparative Physiology and Biochemistry.

ü  Member of the Union of Arab Biologist.

ü  Member on board of the Society "Voice of Mentally Retarded."

ü  Member in the Egyptian Society for Parasitology.

ü  Member of the International Councils for Preventive, Predictive and Personalized Medicine, Moscow.

REVIEWER PANELS

Recorded in the international reviewer panels of:

ü  Medical Sience Monitor Journal, New York.

ü  FEBS Letters – Elsevier.

ü  Journal Acta Tropica

ü  Life Science- Elsevier

ü  Journal nanoparticles Research

ü  Saudi Chemical Society Journal

 

CONFERENCES PARTICIPATED

     - OMICS group 5Th  Conference on Clinical Immunology, Las Vegas, USA, 17-19 October

-    OMICS group conference on Toxicology Summit and EXPO   86th Conference , San Antoni-Texas USA 26-28 Nov, 2012.

-   European strategies in predictive, preventive and personalised medicine: EPMA World Congress,  Moscow1-3 October, 2012.

-     2nd world congress on Phamaceuticals & Novel drug, Delivery Systems” (Pharmaceutica-2012), 20-22 Feb, 2012 in San Francisco, USA.

-     16th International Conference of the Association of Psychology and Psychiatry for Adults and Children (A.P.P.A.C.) Hilton Hotel, in Athens, Greece, on May  17 – 20, 2011

- 1st AMDI International Biohealth Science Conference (IBSC 2010) 29th Nov-1st Dec 2010- Penang, Malaysia.       Keynote Speaker

-   BIT's 3rd Annual Congress of Gene-2009- Foshan- China, 1-7 December, 2009.  Oral presentation.

-     International Workshop on Advanced Materials IWAM, 2009. Ras Al-Khaima. Emarat

-    Participation in Nanotechnology conference which  held in Jordon University- Oman, November 10-14, 2008.

-     Participation in Nanotechnology conference which was held in Jeddah King Abdullah centre for nanotechnology from 17-19 June 2008.

- Participation in conference of Neuroscience, 21-24 January, 2008, Marriott Hotel. Arranged by Military Hospital.

-  8th International Congress of the Egyptian German Society of Zoology, 29-31 March, Tanta, Egypt. 1999.

- The SRP International Conference on Schistosomiasis, March, 15-19, 1998.

- International Congress on Molecular Genetics, Feb., 21-25, 1998, Cairo, Egypt.

- 36 th IUPAC Congress, 18-23 August, 1997, Geneva, Switzerland.

- 7 th International Congress of the Egyptian German Society of Zoology, 3-6 April, 1997, Aswan, Egypt

- 3 rd International Congress of the Union of Arab Biologist, 3-8 Nov., Sent Cathrin, Egypt. 1996.

- The SRP International Conference on Schistosomiasis March, 12-16, 1995, Cairo, Egypt.

- 35th IUPAC Congress, 14-19 August 1995-Istanbul-Turkey.                                                                                                       

-  3 rd  International Congress of Toxicology in Developing Countries,  Nov., 19-23, 1995, Cairo, Egypt.

- Al-Azhar First International Conference on Recent Advances in Pharmaceutical Technology and Biological Sciences , Dec., 19-21, Cairo, Egypt. 1995.

 

RESEARCH PROJECTS

ü  Use of sublethal concentrations of plant molluscicides to control schistosomiasis. Dean of Scientific Research, King Saud University. (150,000 SR).

ü  Relationship between heavy metal pollution and oxidative stress/ impaired energy metabolism of Saudi autistic Children. Sabic Company. (25,000 SR).

ü  Neurological effects of orally administered propionic acid in rats: Possible role on the pathogenesis of autism. SABIC Company. (50,000 SR)

ü  Deanship of Scientific Research at King Saud University funding through the research group   project No (RGP-VPP-005).

 

PATENTS

ü  Disturbance of Schistosome-Snail interaction without environmental pollution. No 23323 (15/08/2000-15/08/2020). Ministry of state for Scientific Research. Academy of Scientific Research and Technology. Egypt.

DEPATMENTAL AND COLLEGE COMMITTEES

ü  Member in the MsC student's admit ion committee, biochemistry department.

ü  Member in the biochemistry department committee for undergraduate academic strategic plan.  

ü  Member in the King Saudi university accreditation committee (Representitve of the Biochemistry Department, female section).

ü  Member of the internal reviewers committee of female centre in malaz

ü  (a temporary committee for evaluation of different departments for academic accreditation).

ü  Member in the college committee for evaluating standard 10 (Scientific Research) for the accreditation process

 

Awards

ü  Recognized publication awards for six of the recently published papers.

ü  Recognized teaching staff award at the departmental level 1431-1432.

List of Publications

       1. Association of social and cognitive impairment and biomarkers in autism spectrum disorders.   Journal of Neuroinflammation 2014, 11:4

                     

     2.      The neurotoxic effect of clindamycin - induced gut bacterial imbalance and orally administered propionic acid on DNA damage assessed by the comet assay: protective potency of carnosine and carnitine. Gut Pathogens 2013, 5:9

 

3.      Possible ameliorative effects of antioxidants on propionic acid / clindamycin - induced

neurotoxicity in Syrian hamsters. Gut Pathogens 2013, 5:32

4.      Protective and therapeutic potency of N-acetyl-cysteine on propionic acid-induced biochemical autistic features in rats Journal of Neuroinflammation 2013, 10:4

5.      Comparative study on the protective effect of carnosine and carnitine against pro-inflammatory/pro-oxidant effects of clindamycin and propionic acid administrations to hamsters African Journal of Microbiology Research Vol.7(2) , pp. 103-114 , January 201

6.      2. Detoxification mechanisms in autism spectrum disorders. OA Autism 2013 Aug 01;1(2):19. 

7.       Role of Gut-Brain axis in the etiology of neurodevelopmental disorders. Clinical Toxicology. 2013

8      Lipid  mediators in plasma of autism spectrum disorders.  Lipids in Health and Disease

2012, 11:160

 

9.      Identification of potential biomarkers of gold nanoparticle toxicity in rat brains. Journal of Neuroinflammation 2012, 9:123

 

10.       Neuroinflammation  in  autism  spectrum disorders. Journal of Neuroinflammation 2012, 9:26

11.  Impaired plasma phospholipids and relative amounts of essential polyunsaturated fatty acids in autistic patients from Saudi Arabia in Lipids in Health and Disease(2011)

12.  Plasma fatty acids as diagnostic markers in autistic patients from Saudi Arabia.  Lipids in Health and Disease(2011)

13.  Relationship between chronic lead toxicity and plasma neurotransmitters in autistic patients from Saudi Arabia. Clinical Biochemistry (2011) 44(13, 1116-1120

14.  Novel metabolic biomarkers related to sulfur dependent detoxification pathways in autistic patients of Saudi Arabia. BMC Neurology 2011, 11:139

15. Proinflammatory and proapoptotic markers in relation to mono and di-cations in plasma of autistic patients from Saudi Arabia .J Neuroinflammation. 2011; 8: 142. 

 

16.  Etiology of autistic features: the persisting neurotoxic effects of propionic acid  Journal of Neuroinflammation 2012, 9:74

 

17.  A novel study on amyloid β peptide 40, 42 and 40/42 ratio in Saudi autistics. Behavioral and Brain Functions 2012, 8

18.  Mechanism of nitrogen metabolism-related parameters and enzyme activities in the pathophysiology of autism Journal of Neurodevelopmental Disorders 2012, 4:4

19.  Oxidative stress and antioxidant status in Saudi Asthmatic patients. Clinical Biochemistry, 2011.

20.  Oxidative stress and antioxidant status in Saudi asthmatic patients. Clinical Biochemistry, In Press, Corrected Proof, Available online 12 February 2011

21.  On the biochemial phenomenon of nanoparticles-protein interactions. J. Nanoparticles Research 2012 Review article.

22.  Nanoparticles labeled stem cells: A novel therapeutic vehicle. Journal “Clinical Pharmacology: Advances and Applications”2010,2:9-16

23. Key Glycolytic enzymes as biomarkers in plasma of Saudi autistic children. Open access Journal clinical trials 2010, 2:1

24..  Measurement of selected ions related to oxidative stress and energy metabolism in Saudi autistic children. Clinical Biochemistry 2009.

25. Biomarkers Discovery Of neurological Diseases: A metabolomic approach. Open access Journal clinical trials 2009.

26.  On the toxicity of therapeutically used nanoparticles: An overview. J Toxicology (2009).

 

27.  Metabolic biomarkers related to oxidative stress and antioxidant status in Saudi autistic children. Clinical Biochemistry,  2009, 42: 1032-1040.

28.  Metabolic biomarkers related to energy metabolism in Saudi  autistic children. Clinical Biochemistry, 2009, 42: 949-957.

29.  Effect of sublethal concentration of Solanum nigrum on transaminases and lactate dehydrogenase of Biomphalaria Arabica, in Saudi Arabia. J. Egypt. Soc. Parasitol. 37(1):39-50 (2007).

30.  Induced changes in the amino acid profile of Biomphalaria alexandrina molluscan host to Schistosoma mansoni using sublethal concentrations of selected plant molluscicides. J Applied Sciences (2007).

31.  Important aspects of Schistosome – Biomphalaria interactions as target for antischistosome drug . Medical Science Monitor 12 (12): 282-292 (2006).

32.  Review:  Stage-specific expression of schistosome proteins as potential target for drug design. Medical Science Monitor 11(3) :94-103 (2005).

33.  Histological and Histochemical studies on mice liver-treated with curcuma longa or praziquantel. Egypt. Pharm. J. 5 (1): 77-101 (2005)

34.  On the pathogenicity of attenuated  Schistosoma mansoni cercariae released from metabolically disturbed Biomphalaria alexandrina. J. Egypt. Soc. Parasitol. 33 (3). 777-794 (2003).

 

35.  Review: Biochemical and immunological adaptation in schistosome parasitism. Comp. Biochem. Physiol 136 (B), 227-243 (2003).

36.  Antibilharzial evaluation of different extract of Hydrangea hortensis. Bull. Fac. Pharm. Cairo Univ. 41(3),(2003).

37.  Effects of carnosine on bilharzial infestation in hamsters : biochemical and histochemical studies. Comp. Biochem. Physiol. 131 (B), 535-542. (2002).

38.  Effect of carnosine administration on certain metabolic parameters in bilharzial- infected hamsters. Comp. Biochem. Physiol. (2001).

39.  Biochemical study on Dimethoate chronic toxicity in rats and the protective effects of different diets. Med. J. of Cairo University . 69, 151-159 (2001).

40. Effect of schistosomal infection and its treatment with Curcuma longa extract on some bioenergetic parameters in mice livers. Bull. NRC, Egypt, 26(1), 61-69 (2001).

 

41.  In vivo, attenuation of schistosome cercarial development and disturbance of egg laying capacity in Biomphalaria alexandrina using sublethal concentration of plant molluscicides. J. Egypt. Soc. Parasitol, 31(3),657-669 (2001).

42.  SDS_PAGE –separated tissue proteins of Biomphalaria alexandrina in the presence and absence of Schistosoma mansoni infection. J. Egypt. Soc. Parasitol. 30 (1), 125-136 (2000).

43. Schistosoma mansoni:  Susceptibility of Biomphalaria alexandrina snails to Schistosoma mansoni infection: correlation with activity of certain glycolytic enzymes. J. Egypt. Soc. Parasitol. 30 (2), 547-560 (2000).

44.  Sublethal concentrations of Ambrosia maritima (Damsissa) affecting compatibility of Biomphalaria alexandrina snails to Schistosoma mansoni infection through disturbing the glycolytic pathway. J. Egypt. Soc. Parasitol. 30 (2), 809-819 (2000).

 

45.  Kinetic responses of adenylate degrading enzymes in muscles of freshwater snails, molluscan hosts for schistosoma species and a trial to disturb using saponins. Bull. NRC, Egypt, 24,59-73 (1999).

46.  Effect of alkaloids and saponins of plant origin on of  Biomphalaria alexandrina snails. Egypt. J. Bilh.21, 125-144 (1999). 

47.  HPLC analysis of free amino acids in Biomphalaria alexandrina snails under the influence of larval parasitic infection and starvation. Egypt. J. Bilh. 21, 34-51 (1999).

48.  On the factors affecting natural selection between schistosoma parasite and their molluscan intermediate host. . J. Egypt. Ger. Soc. Zool . 26 (D), 87-102 (1998).

 

49.  Some properties and specificity of deoxyribonuclease and ribonuclease of freshwater mollusks hosts and non- hosts to schistosoma parasite. . J. Egypt. Ger. Soc. Zool. 24 (A),35 -47 (1997).

50.  Elucidation of the role of specificity, development and exposure to trematode infection on citrulline, arginine and nitrite levels in freshwater snails. Bull. Egypt. Soc. Physiol. Sci.17(1), 87-97 (1997). 

 

51.  Mechanism of action of acylurea flufenoxuron on larvae of the egyptian cotton leaf worm Spodoptera littoralis. J. Egypt. Ger. Soc. Zool. 21,27-47 (1996).

52.  Comparative studies on polysacharases of freshwater snails target and non-target to schistosoma parasite. J. Union Arab Biol. 6(A),21-33 (1996).

53.  Trace elements profile and kinetic studies of pyruvate kinase in freshwater snails target and non-target to schistosoma parasite. Egypt. J. Bilh. 18,27-38 (1996).

54.  Screening of two pyrazolopyrimidines for schistosomicidal activity and their effect on serum transaminases of albino mice. Egypt. J. Bilh.16, 201-210 (1995).

55.  Alkaline phosphatase and 5- nucleotidase activities and levels of calcium and phosphorus in tissue of some freshwater snails. Egypt. J. Bilh.17, (1995).

56.  Kinetic properties and sensitivity to methotrexate inhibition of dihydrofolate reductase in freshwater snails  Bilh.17, (1995)

57.  Kinetic responses of lactate dehydrogenase and two transaminases during developmental stages  of Biomphalaria alexandrina snails. Egypt. J. Bilh.17, (1995). 

58.  Observations on the use of dursban as a molluscicide on some biological processes in Biomphalaria alexandrina snails. Egypt. J. Pharm. Sci., 35(1-6), 539-552 (1994).

 

59.  Effect of excess vitamin C on certain biochemical parameters in laboratory bred Biomphalaria alexandrina snails. Egypt. J. Pharm. Sci., 35(1-6), 477-487 (1994).

60.  Review:  Factors affecting natural selection between helminthes parasites and their molluscan intermediate hosts with special reference to schistosoma. Comp. Biochem. Physiol. 108 B,397-415 (1994).

61.  Comparative metabolic study of three potent organophosphorous insecticides in Biomphalaria alexandrina snails. Egypt. J. Bilh. 15(1,2),101- 109 (1993).

62.  Effect of some organophosphorous insecticides on amylases and cellulases in Biomphalaria alexandrina snails. Egypt. J. Bilh. 15(1,2),183 -188 (1993).

63.  Synthesis of some Thiazolidianone and Pyrazolidinones of possible inhibitory effect on Biomphalaria alexandrina snails enzymatic activities. Egypt. J. Bilh. 15(1,2),171-181 (1993).

64.  Potential of certain organophosphorous insecticides to Biomphalaria alexandrina snails   and their stability in the aqueous solution. Bull. Fac. Agri. Cairo 44 (2), 433-444 (1993).

65.  Comparative enzymatic studies on 5-azacytidine pre-treated Biomphalaria alexandrina snails. Pakistan Journal of Biochemistry, 25,1-15 (1992).

 

66.  Comparative studies on some hydrolytic enzymes of Biomphalaria alexandrina snails specific intermediate hosts for schistosomiasis. J. Biol. Med. Sci. Ther.8 (4),1-7 (1992).

 

67.  Effect of magnesium and urea on glucose and glycogen content in schistosomiasis intermediate hosts. Bull. NRC. Egypt, 18 (1),49-54 (1992).

68.  Mini review: Metabolic end-products in parasitic helminthes and their molluscan intermediate hosts. Comp. Biochem. Physiol. 101B,499-508 (1992).

69.  Succinate DCPIP and NADH-fumarate oxidoreductases in freshwater snails susceptible and non-susceptible to schistosoma infection. Cell. Mol. Biol 38(2), 131-134 (1992).

 

70.  Synthesis and effect of new tetrahydronaphthyl pyrazolines on carbohydrate metabolism in Bilharzia snails. Bull. Fac. Pharm. Cairo Univ.30(3) 24-31 (1992).

71.  Spectrophotometric and electrophoretic determination of the effect of copper sulphate and bayluscide on some enzymatic activities in Biomphalaria alexandrina snails. Bull. NRC. Egypt, 18 (3),173-188 (1992).

 

72.  Kinetic potentials of certain scavenger enzymes in freshwater snails susceptible and non-susceptible to schistosoma infection. Cell. Mol. Biol.39 (4),449-454. (1992).

73.  54.Biological aspects of controlling snail hosts of bilhaziasis using wild and cultivated plant extract. Annals of agri. Sci. Moshtohor 30 (3), 1531-1539 (1992).

74.  Inhibition of lactate dehydrogenase isoenzyme associated with anaerobic respiration in schistosomiasis intermediate host snails. Cell. Mol.Biol.37 (1),1-7 (1991).

75.  Variation of transaminases and lactate dehydrogenase in irradiated Biomphalaria alexandrina snails. Cell. Mol.Biol.37 (4),385-390 (1991).

76.  Measurement of some hydrolytic enzymes in Biomphalaria alexandrina snails specific intermediate hosts for schistosomiasis. Cell. Mol. Biol.37(3),309-314 (1991).

 

77.  Kinetic properties of two transaminases and lactate dehydrogenase in freshwater snails, specific intermediate hosts for human schistosomiasis. Cell. Mol. Biol.36(4),375-381 (1990).

78.  Measurement of some selected enzymatic activities in infected Biomphalaria alexandrina snails. Cell. Mol.Biol.36(6),367-372 (1990).

 

79.  Selected enzymatic activities in freshwater snails, specific intermediate hosts for human schistosomiasis. Cell. Mol. Biol. 35(2),181-185 (1989).

80.  Genetic studies on freshwater snails, specific intermediate hosts for schistosomiasis. III- Chemical modification through incorporation of 5-bromouracil into deoxyribonucleic acid. Cell. Mol.Biol. 27, 185-203 (1981).

 

81.  Genetic studies on freshwater snails, specific intermediate hosts for schistosomiasis. IV- Gamma radiation as physical mutagen on deoxyribonucleic acid.. Cell. Mol.Biol. 27, 275-277(1981).

82.  Genetic studies on freshwater snails, specific intermediate hosts for schistosomiasis. I- Isolation and base composition determination of  ribonucleic acid (RNA). Cell. Mol. Biol. 26,85-88 (1980).

 

83.  Genetic studies on freshwater snails, specific intermediate hosts for schistosomiasis. I- Isolation and base composition determination of  deoxyribonucleic acid (DNA). Cell. Mol. Biol.26,455-458 (1980).

 

 

Book:

Toxicity of Novel Nanosized Formulations Used in Medicine In: Oxidative stress and Nanotechnology, Methods and protocol.  eds: Donald Armstrong and Dhruba J. Bharali. Publisher:  Humana Press is a brand of Springer. New York ,  London.

 

 

 

 

 

 

 

 

 

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