BCH 442: Molecular Biology - I
Credit hours: 2
Time: 11.00 - 11.50
Days: Sunday & Tuesday
Class room: Building 5, Room 460
Prerequisite: BCH 221
Course Description: The aim of this course is to familiarize the students with the fundamentals of molecular biology. Course contents include purine and pyrimidine metabolism, cell cycle, structure of DNA and RNA. Contents also include replication, transcription and translation, genetic code, regulation of gene expression and genetic engineering.
Grading system: Two continuous exams of 20 marks each and a final exam of 60 marks.
Exam dates and time:
First continuous Assessment: 2/4/1430 H (29/3/2009)
Second continuous Assessment: 8/5/1430 H (3/5/2009)
- Introduction to nucleic acids
- Purine and pyrimidine metabolism
- Cell cycle and cell division
- Structure of DNA
- Mechanism of DNA replication in prokaryotes and eukaryotes
- Mechanism of DNA transcription in prokaryotes and eukaryotes
- Post transcriptional modifications
- Structure of RNAs and ribosomes
- Genetic code
- Translation and post translational modifications and control
- Gene expression
- Regulation of gene expression
- DNA damage and repair
- Recombinant DNA technology and its applications
1. Lippincot's Illustrated Reviews Biochemistry, 3rd edition P. C. Chamoe, R. A. Harvey, D. R. Ferrier, Lippincot William and Wilkins publishers, 2005.
2. Lechninger's Principles of Biochemistry 4th edition. D. L. Nelson and M.M. Cox, Worth Publishers, 2000.
3. Biochemistry and Molecular Biology by William H. Elliott and Daphne C. Elliott, Oxford University Press, Oxford, 2005.