Laila Y. AL-Ayadhi
ليلى يوسف العياضي
(BBMS, MB ChB, PhD)
Laila Y. AL-ayadhi (BBMC, MB ChB, PhD)
Professor of Neurophysiology
Consultant Diagnostic Neurophysiology
KSU-Autism Research and Treatment center
Department of physiology (29)
Faculty of Medicine
King Saud University
P O Box 2925
Riyadh 11461 Saudi Arabia
Fax No. +96614672567
INSTITUTION & LOCATION
FIELD OF STUDY
Kuwait University, Kuwait
Glasgow University, Glasgow, Scotland, UK
Medical house officer/ New Ayr hospital, Scotland, UK
Surgical house officer/ New Ayr hospital, Scotland, UK
Leicester University , England, UK
Full registration with the British medical council
Bachelor of Basic Medical
Bachelor of medicine and
Bachelor of Surgery (MB ChB)
Doctor of Philosophy (PhD)
Biomedical intervention of Autism spectrum disorders
Hyperbaric Oxygen Therapy (HBOT)
Inflammation and free radicals
1- Laila AL-Ayadhi, Ali Altuwajri, A. bekairi. Ischemia- Reperfusion on acute inflammation of the joint in rats: Experimental model, Medical science symposium. January 2000, USA.
2- -AL-Ayadhi L. The influence of academic stress on free radicals on of blood in students during exams. Annals of Saudi Medicine,2003, Vol. 23, No. 1-2, 51-54.
3- AL-Ayadhi L. Oxidative stress and neurodegenerative disease. Neurosciences, 2004; Vol. 9 (1): 19-23.
4- AL-Ayadhi L., AL-Tuwajri A. The synergistic effect of adenosine A2a receptors agonist and type IV phosphodisterase inhibitors and K channels activators on PMNLs free radicals production. Pharmacological Research, 2004; Vol. 50(2): 157-163
5- AL-Ayadhi L. Sex hormones, personality characters and professional status among Saudi females. Saudi Medical Journal, 2004 Vol 25 No. 6:711-716
6- AL-Ayadhi L. The Anti-Inflammatory Effects of Petroleum Ether, Chloroform and Methanol Extracts of Pomegranate (Punica Granatum) Peel and Seeds Extracts. THE 7TH INTERNATIONAL SYMPOSUM OF THT MIRACULOUS OF QURAN AND SUNAH, DUBAI, UAE, 2-4 SAFAR 1425. Allied Medical Science Section, pp 1-12.
7- AL-Ayadhi L. The effect of adrenomedullin on oxygen free radicals production and aggregation of isolated human polymorphoneuclear leukocyte. Saudi Pharmaceutical Journal2004; Vol. 12 (2-3):80-85.
8- AL-Ayadhi L. Neurohormonal changes in medical students during academic stress. Annals of Saudi Medicine 2005; 25 (1): 36-40.
9- AL-Ayadhi L. Altered Oxytocin and Vasopressin levels in Autistic children in Riyadh Area. Neurosciences 2005; Vol. 10 (1):47-50
10- AL-Ayadhi L. Pro-inflammatory Cytokines in Autistic children in Riyadh Area, Saudi Arabia. Neurosciences 2005; Vol. 10 (2):155-158
11- AL-Ayadhi L. Heavy Metals and Trace Elements in Hair Samples of Autistic and Normal Children in central Saudi Arabia. Neurosciences 2005; Vol. 10 (3): 213-218.
12- AL-Ayadhi L. Arginine, Omega-3 fatty acids and nucleotide-enriched diet augment the anti-inflammatory effect of diclofenac on carrageenan-induced rat paw edema. Saudi Medical Journal 2005 ; Vol. 26 (7):1146-1149.
13- AL-Ayadhi L. The autoimmune Connection of Autism in Riyadh area. Neurosciences 2005; Vol. 10 (4): 265-267.
14- AL-Ayadhi L. Gluten sensitivity in Autistic children in Riyadh area. The paper will be published in the Neurosciences issue 2006; Vol. 1 (1).
15- Al-Ayadhi L, Aida A. Korish, Ali S. Al-Tuwaijri. The effect of vitamin E, L-arginine, N-nitro L-arginine methyle ester and Forskolin on endocrine and metabolic changes of rats exposed to acute cold stress Saudi Med J 2006; Vol. 27 (1): 17-22
16- Al-Ayadhi L. Auditory Brainstem Evoked Response in Autistic in Central Saudi Arabia. Neurosciences 2008, Vol. 1 (1).
17- Al-Ayadhi L. Increased Oxygen Free Radical Production from Isolated Human PMNLs and whole blood by luminol-enhanced Chemiluminescence in Autistic children. Being revised by Kuwait medical Journal
18- Al-Ayadhi L. Serum Levels of Brain-Derived Neurotrophic Factor (BDNF) in Autistic Children in central Saudi Arabia. Being revised by Pakistan Journal of medical sciences.
19- Ali Altuwaijri and L. Al Ayadhi. Effect of combination of heavy metals on respiratory burst of isolated human polymorphonuclear leukocyte The FASEB Journal. 2007;21:904.8)
20- Hatem A, AL-Gadani Y, AL-Ayadhi L, Al-Atass O. Metabolic biomarkers of oxidative stress in autistic children in central Saudi Arabia 2008.the 16th neurosciences symposium. Intercontinental hotel.
Employment and Administrative History
– 1- Associate professor in Neurophysiology, from February 2005 until current
2- Assistant professor, department of physiology, Faculty of medicine, King Saud University, 10/ 1999 G (18/6/1420) until February 2005
– 3- Junior house officer- Internal Medicine- Ayr Hospital- Ayr- Scotland UK (1 /8 / 1992 G)
4- Junior house officer- General Surgery - Ayr Hospital- Ayr- Scotland UK (1 / 2 / 1993 G
– 1- 211 PSL, Course supervisor, (First year Dental student) 2005, 2006, 2007)
2- 131 PSL Course supervisor, (First year Medical student, course in General physiology) for three academic years, (2003, 2004)
– 3- Head of the female section of the Department, for three years (from 2000-2003)
Scholarships and Awards:
1- Award from King Abdul Aziz City for Science and Technology, Riyadh Saudi Arabia. Funding project No. LGP- 6- 27, for the period between 15-10- 2002 to 15- 10- 2003. Title: Studies on the effect of a combination of adenosine A2A receptor agonists and selective type IV phospho-diesterase (type IV PDE) inhibitors on neutrophil respiratory burst and rat’s paw edema
2- Award from King Abdul Aziz City for Science and Technology, Riyadh Saudi Arabia. Funding project No. LGP- 7- 33, for the period between 10-11- 2004 to 10- 11- 2005. Titel: Study of trace elements in the hair from autistic, autistic like and control children of Saudi Arabia in Riyadh area
3- Award from Deanship of Scientific Research, King Saud University, Riyadh Saudi Arabia. Funding project No.DSR 17, for the period between 1-4- 2004 to 1- 4- 2006. Title: A study of neuroendocrin & electrophysiological brainstem auditory evoked potential patterns in Saudi children in Riyadh area
1- Supervisor for a PhD degree ((Study of Heavy metals, trace elements, and free radicals in Alzheimer's patients in Riyadh Area , Saudi Arabia), from 2005
2- Supervisor for Master degree ((study of Oxidative stress biomarkers in autistics in Saudi Arabia)), 2007
Participation in Conferences, Symposia and Other Activities:
Participation in conferences and symposia
1- Laila A-ayadhi, Ali Altuwajri, A. bekairi. Ischemia- Reperfusion on acute inflammation of the joint in rats: Experimental model, Medical science symposium. January, 2000, USA. (Poster)
2- Year 2001 Epilepsy workshop for health care professionals, King Faisal Specialist hospitals, 4 April- 2001 (10 Muharam 1222 (Attendance).
3- Medical education workshop-Assessment, King Khaled University Hospital, 27 0ctober 2002(21 Shaban 1223),Attendance
4- Year 2003 Epilepsy update for health care professionals, King Faisal Specialist hospitals, 21-22 September- 2003 (24-25 Rajab 1224 (Attendance).
5- Muscular Dystrophy and Related conditions, King Faisal Specialist hospitals, 29-30 September- 2003 (3-5 Shaban 1224 (Attendance)
6- The Seventh Symposium of New Technology and its Effect on Human and Environment, King Saud University, 1423 (Attendance, preparation committee for the symposium)
7- Clinical nutrition symposium, Security Force Hospital, Riyadh (14-15 March 2004)
8- The first international symposium on Autism and Neurodevelopmental disorders 25-28 September 2004). Presentation: Mumps, Rubella, Measles and Myelin Basic Protein serology in autistic children in Riyadh area.
9- Surgical and Medical aspects of Neurendocrine disorders, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia, April 3-4 2007
Membership of Scientific Associations:
1- Fully registered with the British General Medical Council (GMC) 1993
2- Member of the British neurosciences association (BNA) 2004
3- Member of the Saudi Pediatric association (SPA) 2004
4- Member of cure Autism Now (CAN) 2004
5-Member of the Saudi Pediatrics Association
6- Listed with Marquis Whose Who in the world for 2005, 2006,2007
The researcher is trained in the following aspects:
1- Extracellular and intracellular recording techniques from smooth muscle cells
2- Mechanical contraction recording techniques from smooth muscle cells
3- Histochemical staining techniques under light and electron microscopy
4- Measurement and analysis of free radicals production from whole blood and white blood cells.
5- Measurement and analysis of inflammation in vivo (rat paw edema)
6- Measurement and analysis of pyrexia in vivo
7- Measurement of hormones from blood samples using ELIZA
University and Community Service:
1- Public lecture (Is it possible to solve the Puzzle—AUTISM), SPECIAL ACADEMY, Riyadh – 12 -10- 1424
2- Public lecture (Cause and Theories on Autism), Autism Center, Riyadh – 12 -10- 1424
3- Group therapy for mothers with Autistic children Group training on the internet to mother of Autistic children on how to obtain recent information on Autism.
4- Global reviewer for the Saudi Medical Journal
5- Pulic lecture ( The result of the first Medical study on autism in Riyadh area , Saudi Arabia), April 2006, King Faisal Specialist Hospital
6- Public lecture (oxidative stress and autism), Azzam Autism center, January 2007
7- Offering free of charge Biomedical Medical intervention consultation for Autistic