King Saud University
Department of Clinical Laboratory Sciences
CLS 241 Haematology Syllabus
Dr. Abdullah Aljedai
Tues: 10 - 12 AM
Haematology is a science that deals with blood and its components, their structure,
function, and disorders. The course will be 4 credit hours. Two credit hours will be
designated for lectures and two credit hours for laboratory.
The course will contain an introductory part, in which basic concepts of haematology
are introduced and major terms are defined; then, specialized topics will be tackled in
a systematic approach to cover the major diseases of blood and its components.
The course is especially designed for undergraduate students who intend to work in
diagnostic laboratories. Upon the completion of the course, students would have
benefited form the following objectives of the course:
1. Explain major concepts in haematology, including haemopoiesis, bone marrow
structure, blood composition, and functions of blood components.
2. Elucidate the basis of blood diseases, including anemias, haemoglobinopathies,
bleeding disorders, and haematological malignancies
3. Clarify in detail the major concepts regarding blood transfusion, and bone marrow
4. Provide the latest information regarding the newest techniques utilized by
haematologists to treat and diagnose haematological disorders, including stem
cell purification and transplantation, flow cytometry analysis, and molecular
HLA matching techniques.
In the classroom:
• Generally, the teaching material will be introduced in an interactive
• Absence form class for >25% of total class time will lead to dismissal from the
• Related questions are strongly encouraged in the class.
Recommended study approach:
• Students should attend all lectures and not miss any lecture time.
• Students should not depend solely on lecture materials and are encouraged to read
text books and other online resources to gain an in-depth knowledge of the module.
• Additionally, for each lecture, the student should prepare and follow up with
sufficient studying time to cover the material presented in the class during that lecture.
• It is highly advised not to accumulate material until before the examination time.
Cramming will definitely weaken the student's ability to understand and retain
• After-class questions can be presented directly to the instructor
during advertised office hours, or can be emailed to:
CLS 241: Lecture Schedule
1 Haemopoiesis: physiology and pathology of Red cells and platelets
2 Granulocytes, Monocytes, and reticuloendothelial system
3 Benign disorders of white cells
4 Red cell disorders
5 Blood coagulation and Haemostasis
6 Iron: Physiology and deficiency, iron Overload and sideroblastic
7 Megalohlastic anaemia:Vitamin B12, and Folate deficiency
8 Haemolytic anaemias: Genetic defects of haemoglobin
9 Inherited defects of haemogolobin-sickle cell disease
10 Haematological malignancies-General concepts
11 Acute leukaemia
12 Chronic lymphocytic leukaemia
13 Myeloproliferative disorders
14 Diagnosis of haematolgical malignancies by flow cytometry
CLS 241 Laboratory Schedule
1 Collection of blood from patients
2 Basic haematological techniques
3 Preparation and staining methods for peripheral blood and bone marrow films
4 Blood-cell morphology in health and disease
5 Blood-cell cytochemistry and supplementary techniques
6 Laboratory methods used in the investigation of the haemolytic anaemias
7 Investigation of the hereditary haemolytic anaemias
8 Investigation of the haemoglobinopathies
9 Laboratory methods used in the investigation of paroxysmal nocturnal
10 Quantitative assay of coagulation factors
11 Investigation of platelet function
12 Laboratory control of anticoagulant and thrombolytic therapy
13 Investigation of megaloblastic and iron-deficiency anaemias
14 Miscellaneous tests
1- Essential Haematology, 5th Ed., 2006
Authors: A. V. Hoffbrand, J.E. Pettit, P. Moss
1. Blackwell Science, Inc., 350 Main St., Malden, Massachusetts, 02148, USA.
2. Blackwell Publishing Ltd., 9600 Garsington Road, Oxford, OX4 2DQ, UK.
2- Practical Hematology
Authors: Sir John V. Dace & SM Lewwis
ISBN: 0 443 01981 9
1-Theory examination (20% Med Term and Final 30%);
2- Assignment (10%).
3- Practical examination (20% Med Term and 20% Final)