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PHC 471 

PHC 471

Medicinal Chemistry IV

(2+1)

 

Course Description:

 

 

 

The study of the structures, nomenclatures, synthesis, interaction of drugs with the receptor sites, structure‑activity relationship, metabolism of the different chemical classes of Chemptherapeutic agents and Endocrinological agents.

 

 

 

 

Topics:

 

 

Topic

A

 

Chemotherapy:

  1. Introduction to chemotherapy, theory of selective toxicity

  2. Synthetic antimalarials

  3. Sulfonamides

  4. Anti mycobacterium agents

  5. Antiamebic agents

  6. Anthelmintic agents

  7. Antiviral and antifungal agents

  8. Cancer chemotherapy (Antineoplastic agents):

  • Introduction

  • Antimetabolites

  • Alkylating agents

  • Miscellaneous antineoplastic agents

 

 

 

 

 

 

 

 

B

Diagnostic agents.

C

Hypoglycemic agents.

D Thyroid and antithyroid agents.
     
Text books:  

 

 

Principles of Medicinal Chemistry

 

 
Related Links:  

 

 

1- National Cancer Institution.

2- American Diabetes Association.

3- The Endocrine Society.