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George E. Carvell, PhD, PT   University of Pittsburgh
One of the earliest attempts to study the motor system was done by C. Sherrington, a British neurophysiologist. Much of his work was conducted with ‘reduced’ preparations where portions of the nervous system were isolated to simplify the system. Sherrington has had a major influence in neurophysiology. He coined the term synapse, motor unit, final common pathway, reciprocal inhibition and using relatively crude equipment (by today’s standards) meticulously described many fundamnetal reflex circuits. His last student, John Eccles went on to record intracellular potentials from spinal neurons that form the neural basis for reflexes and other actions.
C.S. Sherrington with his last student, John Eccles; portrait by Stan Smith, Univ of Oxford
Sir Charles Sherrington was a pioneer in neurophysiology. His student John Eccles recorded intracellular membrane potentials in spinal cord interneurons & motoneurons to reveal synaptic events associated with facilitation and inhibition- mechanisms responsible for spatiotemporal integration in the CNS.
Monosynaptic Stretch Reflex (Deep Tendon Reflex) fig 13.17
fig 13.17
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