RESEARCH AND PUBLICATIONS:
· Al-Suwaidan SN, Gad el Rab MO, et al. Allergic contact dermatitis from myrrah, a topical herbal medicine used to promote healing. Contact Dermatitis 1998; 39(3):137.
· Al-Suwaidan SN, Feldman SR. Clearance is not a realistic expectation of psoriasis treatment. J Am Acad Dermatol 2000; 42:796-802.
ABSTRACT:BACKGROUND: Psoriasis is a disease with many manifestations for which numerous treatments are available. OBJECTIVE: The purpose of this article is to assess whether complete clearance is a realistic expectation given the currently available treatments for psoriasis. METHODS: Clinical trials of the treatment of psoriasis were identified from the medical literature, and the reported rates of clearance were compared. RESULTS: The percentage of patients who experienced complete clearing of their psoriasis varied with the different monotherapy treatments from 2% with tazarotene gel to a maximum of 86% with narrow-band UVB. Combinations of systemic retinoids (etretinate, acitretin) and photochemotherapy (PUVA) attained the maximum reported clearance rate as combination therapy. CONCLUSION: The new treatments available for psoriasis give physicians new opportunity to control the severity of psoriasis. Despite the availability of novel treatments for psoriasis, complete clearing of psoriasis is obviously not a realistic expectation of topical treatment. Phototherapy and systemic therapy provide greater improvement, but studies rarely report complete clearing of the disease as an endpoint. At this time, optimal therapy consists of using combinations of different treatments to obtain short-term improvement and long-term control of the disease.
· Al-Ghamdi A, Al-Suwaidan SN et al. Lichen planus exacerbated by Interferon alpha-2a for chronic viral hepatitis C. The Saudi Journal of Gastroenterology 2000; 6(3): 151-162
· Feldman SR, Al-Suwaidan SN. Clearance in psoriasis treatment. J Am Acad Dermatol 2001; 45: 154 (letter)
· Feldman SR, Al-Suwaidan SN. Clearance can be a realistic expectation of psoriasis treatment. J Am Acad Dermatol 2001; 45: 476 (letter)
· Jokin Y, Al-Suwaidan SN. Pediatric Dermatology: the eye/skin connection. Presented with syllabus in the conference of Pediatric Dermatology for the Practitioner held in San Diego, California, USA. April 20-22, 2001
· Al-Suwaidan SN, Eichenfield LF. Port Wine Stain. In Lebwohl M. Treatment of Skin Diseases, 1st edition. London: Harcourt Publishers Limited, 2002: p160
· Bernard LA, Al-Suwaidan SN et al. A Rosacea-like granulomatous eruption in a patient receiving Tacrolimus ointment for Atopic Dermatitis. Arch Dermatol 2003; 139: 229-31
· Wilson JR, Al-Suwaidan SN et al. Treatment of psoriasis in children: Is there a role for antibiotic therapy and tosillectomy. Pediatr Dermatol 2003, 20:11-5
ABSTRACT: Numerous studies implicate subclinical or recurrent streptococcal infection as a trigger or maintenance factor in the pathogenesis of psoriasis in children. The purpose of this article is to review the efficacy of antibiotic therapy and tonsillectomy as treatments for childhood psoriasis. Clinical trials assessing the efficacy of antibiotics or tonsillectomy as treatments for childhood psoriasis were identified with a search of the medical literature and the results were compared. Only one controlled clinical trial was identified and it did not find a significant effect of antibiotic treatment on psoriasis. In other studies, the percentage of psoriasis patients who experienced disease clearance with antibiotic therapy ranged from 0% to 55%, with no patients experiencing disease worsening during treatment. No controlled trials of tonsillectomy for psoriasis were identified. The percentage of patients who experienced disease clearance after tonsillectomy in uncontrolled trials ranged from 32% to 53% and a similar percentage reported significant improvement in their psoriasis, with a maximum of 7% noting worsening of the disease after the operation. The available evidence does not demonstrate the efficacy of either antibiotic therapy or tonsillectomy in the treatment of childhood psoriasis. Because these treatments are relatively benign compared to other treatments for severe psoriasis, the use of antibiotic therapy or tonsillectomy may still be worth considering, especially for those patients with recurrent streptococcal infections that seem to trigger or maintain their skin disease.
· Chen B, Al-Suwaidan SN et al. Retrospective analysis of 204 patients with facial Hemangiomas treated with the Pulsed Dye Laser, Oral and Intralesional Corticosteroids (In press)
· Al-Suwaidan SN, Bergman JN et al. Giant Juvenile Xanthogranuloma and review of the literature. (In press)
· PHACES Syndrome: the first reported case in Saudi Arabia (In press)