Examination Model CLS241

 

a)             1- Megaloblastic anaemia is best indicated by:

a)        Low haemoglobin level

b)        High MCV value

c)        High MCHC value

d)        Low PCV value

e)        All of the above

 

b)             2- Macrocytosis is caused by:

a)        Folic acid deficiency

b)        Liver diseases

c)        Vitamin B12 deficiency

d)        All of the above

e)        a and c

 

3- Vitamin B12:

a)        Requires IF for absorption

b)        Its deficiency is common in vegans

c)        Its deficiency is also caused by Transcobolamin deficiency

d)        Its absorption is measured indirectly by Schilling technique

e)        All of the above

 

 

4- Folic acid:

a)        Is synthesized by micoorganisms

b)         Is absorbed in the large intestine

c)         Plays a role in DNA synthesis

d)         All of the above

e)         b and c

 

5. Pernicious anaemia is caused mainly by:

a)        Absence of the intrinsic factors

b)        Deficiency of folic acid

c)        Deficiency of vitamin B12

d)        Alcoholism

e)        Haemolytic reaction

 

 

6- Vitamin B12 deficiency leads to:

a)        Folic acid deficiency

b)        Megaloblastic anaemia

c)        Neuropathy

d)        All of the above

e)        b and c

 

7- A haemolytic anaemia due to membrane abnormality is:

a)        Hereditary elliptocytosis

b)        Sickle cell anaemia

c)        Thalassaemia

d)        G6PD deficiency

e)        Haemolytic disease of the newborn

 

8- The red cell survival rate is best indicated by:

a)        51Cr labelling

b)        Reticulocytosis

c)        Raised serum bilirubin

d)        Osmotic fragility

e)        Fragmented cells

 

9- In chronic haemolytic anaemia:

a)        Folate is deficient

b)        Serum bilirubin is raised

c)        Urinobilinogen is raised

d)        All of the above

e)        b and c

 

10. Intravascular haemolysis is caused by:

a)         Paroxysmal nocturnal haemoglobinuria

b)        G6PD deficiency with oxidant stress

c)        Mismatched ABO blood transfusion

d)        Autoimmune haemolytic anaemia

e)        All of the above